Esreboxetine

DB12395

small molecule investigational

Deskripsi

Esreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia.

Struktur Molekul 2D

Berat 313.3908
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

677 Data
Buprenorphine Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Hydrocodone Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Magnesium sulfate The therapeutic efficacy of Esreboxetine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Esreboxetine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Mirtazapine Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Orphenadrine Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Pramipexole Esreboxetine may increase the sedative activities of Pramipexole.
Ropinirole Esreboxetine may increase the sedative activities of Ropinirole.
Rotigotine Esreboxetine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Esreboxetine.
Sodium oxybate Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Thalidomide Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Esreboxetine.
Dicoumarol The risk or severity of adverse effects can be increased when Esreboxetine is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Esreboxetine is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Esreboxetine is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Esreboxetine is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Esreboxetine is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Esreboxetine is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Esreboxetine is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Esreboxetine is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Esreboxetine is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Esreboxetine is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Esreboxetine is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Esreboxetine is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Esreboxetine is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Esreboxetine is combined with (S)-Warfarin.
Ethanol Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Esreboxetine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Fluvoxamine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Esreboxetine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Esreboxetine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Esreboxetine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Esreboxetine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Esreboxetine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Esreboxetine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Esreboxetine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Esreboxetine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Esreboxetine is combined with Alaproclate.
Iobenguane Esreboxetine can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zopiclone The risk or severity of adverse effects can be increased when Esreboxetine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Esreboxetine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Esreboxetine.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Esreboxetine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Esreboxetine.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Esreboxetine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Esreboxetine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Esreboxetine.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Esreboxetine.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Esreboxetine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Esreboxetine.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Esreboxetine.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Esreboxetine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Esreboxetine.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Esreboxetine.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Esreboxetine.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Esreboxetine.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Esreboxetine.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Esreboxetine.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Esreboxetine.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Esreboxetine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Esreboxetine.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Esreboxetine.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Esreboxetine.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Esreboxetine.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Esreboxetine.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Esreboxetine.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Esreboxetine.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Esreboxetine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Esreboxetine.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Esreboxetine.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Esreboxetine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Esreboxetine.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Esreboxetine.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Esreboxetine.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Esreboxetine.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Esreboxetine.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Esreboxetine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Esreboxetine.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Esreboxetine.

Target Protein

Sodium-dependent noradrenaline transporter SLC6A2

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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