Benzbromarone

DB12319

small molecule investigational withdrawn

Deskripsi

Benzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.

Struktur Molekul 2D

Berat 424.083
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

382 Data
Cyclosporine Cyclosporine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Troglitazone Troglitazone may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Erythromycin Erythromycin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Reserpine Reserpine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Progesterone Progesterone may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Chlorpromazine Chlorpromazine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Cimetidine Cimetidine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Bosentan Bosentan may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Tipranavir Tipranavir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ethinylestradiol Ethinylestradiol may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Glyburide Glyburide may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ketoconazole Ketoconazole may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ursodeoxycholic acid Ursodeoxycholic acid may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Cholic Acid Cholic Acid may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Fusidic acid Fusidic acid may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Simeprevir Simeprevir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Lenvatinib Lenvatinib may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Letermovir The excretion of Letermovir can be decreased when combined with Benzbromarone.
Valinomycin Valinomycin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Olmesartan Olmesartan may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Pralsetinib Pralsetinib may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Quinidine Quinidine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Benzbromarone.
Nitrofurantoin The serum concentration of Nitrofurantoin can be increased when it is combined with Benzbromarone.
Pegloticase The risk or severity of adverse effects can be increased when Benzbromarone is combined with Pegloticase.
Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Benzbromarone.
Liothyronine The excretion of Liothyronine can be decreased when combined with Benzbromarone.
Conjugated estrogens The excretion of Conjugated estrogens can be decreased when combined with Benzbromarone.
Raloxifene The excretion of Raloxifene can be decreased when combined with Benzbromarone.
Caspofungin The excretion of Caspofungin can be decreased when combined with Benzbromarone.
Methotrexate The excretion of Methotrexate can be decreased when combined with Benzbromarone.
Enalapril The excretion of Enalapril can be decreased when combined with Benzbromarone.
Sumatriptan The excretion of Sumatriptan can be decreased when combined with Benzbromarone.
Mycophenolate mofetil The excretion of Mycophenolate mofetil can be decreased when combined with Benzbromarone.
Penicillamine The excretion of Penicillamine can be decreased when combined with Benzbromarone.
Dinoprostone The excretion of Dinoprostone can be decreased when combined with Benzbromarone.
Fexofenadine The excretion of Fexofenadine can be decreased when combined with Benzbromarone.
Benzylpenicillin The excretion of Benzylpenicillin can be decreased when combined with Benzbromarone.
Ouabain The excretion of Ouabain can be decreased when combined with Benzbromarone.
Liotrix The excretion of Liotrix can be decreased when combined with Benzbromarone.
Atrasentan The excretion of Atrasentan can be decreased when combined with Benzbromarone.
Ambrisentan The excretion of Ambrisentan can be decreased when combined with Benzbromarone.
Gimatecan The excretion of Gimatecan can be decreased when combined with Benzbromarone.
Temocapril The excretion of Temocapril can be decreased when combined with Benzbromarone.
Cholecystokinin The excretion of Cholecystokinin can be decreased when combined with Benzbromarone.
Gadoxetic acid The excretion of Gadoxetic acid can be decreased when combined with Benzbromarone.
Technetium Tc-99m mebrofenin The excretion of Technetium Tc-99m mebrofenin can be decreased when combined with Benzbromarone.
Fimasartan The excretion of Fimasartan can be decreased when combined with Benzbromarone.
Paritaprevir The excretion of Paritaprevir can be decreased when combined with Benzbromarone.
Tenofovir alafenamide The excretion of Tenofovir alafenamide can be decreased when combined with Benzbromarone.
Selexipag The excretion of Selexipag can be decreased when combined with Benzbromarone.
Grazoprevir The excretion of Grazoprevir can be decreased when combined with Benzbromarone.
Elagolix The excretion of Elagolix can be decreased when combined with Benzbromarone.
Voxilaprevir The excretion of Voxilaprevir can be decreased when combined with Benzbromarone.
Levosalbutamol The excretion of Levosalbutamol can be decreased when combined with Benzbromarone.
Glecaprevir The excretion of Glecaprevir can be decreased when combined with Benzbromarone.
Dexamethasone Dexamethasone may increase the excretion rate of Benzbromarone which could result in a lower serum level and potentially a reduction in efficacy.
Deoxycholic acid Deoxycholic acid may increase the excretion rate of Benzbromarone which could result in a lower serum level and potentially a reduction in efficacy.
Taurocholic acid Taurocholic acid may increase the excretion rate of Benzbromarone which could result in a lower serum level and potentially a reduction in efficacy.
Dexamethasone acetate Dexamethasone acetate may increase the excretion rate of Benzbromarone which could result in a lower serum level and potentially a reduction in efficacy.
Pravastatin Pravastatin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Fluvoxamine Fluvoxamine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Nelfinavir Nelfinavir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Indinavir Indinavir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ranolazine Ranolazine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Diethylstilbestrol Diethylstilbestrol may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Isradipine Isradipine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Flucloxacillin Flucloxacillin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Atenolol Atenolol may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Terfenadine Terfenadine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Cerivastatin Cerivastatin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ritonavir Ritonavir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Atropine Atropine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Nicardipine Nicardipine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Efavirenz Efavirenz may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Simvastatin Simvastatin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Fluorescein Fluorescein may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Disulfiram Disulfiram may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Cefaclor Cefaclor may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Mifepristone Mifepristone may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Tinidazole Tinidazole may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Repaglinide Repaglinide may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Telmisartan Telmisartan may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ezetimibe Ezetimibe may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Dipyridamole Dipyridamole may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Felodipine Felodipine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Fenofibrate Fenofibrate may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Nitrendipine Nitrendipine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Atorvastatin Atorvastatin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Nifedipine Nifedipine may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Nefazodone Nefazodone may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Ofloxacin Ofloxacin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Clarithromycin Clarithromycin may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Budesonide Budesonide may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Saquinavir Saquinavir may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Prasterone sulfate Prasterone sulfate may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Indocyanine green acid form Indocyanine green acid form may decrease the excretion rate of Benzbromarone which could result in a higher serum level.
Pilsicainide Benzbromarone may decrease the excretion rate of Pilsicainide which could result in a higher serum level.
Dihydroergocristine Benzbromarone may decrease the excretion rate of Dihydroergocristine which could result in a higher serum level.
Glycyrrhizic acid Benzbromarone may decrease the excretion rate of Glycyrrhizic acid which could result in a higher serum level.

Target Protein

Anoctamin-1 ANO1
Solute carrier family 22 member 12 SLC22A12
Multidrug resistance-associated protein 1 ABCC1
Cytochrome P450 2C9 CYP2C9
Cytochrome P450 2C19 CYP2C19

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Uroleap

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul