Simendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Ivabradine | Ivabradine may increase the QTc-prolonging activities of Simendan. |
| Metoprolol | Metoprolol may increase the arrhythmogenic activities of Simendan. |
| Lidocaine | Lidocaine may increase the arrhythmogenic activities of Simendan. |
| Atenolol | Atenolol may increase the arrhythmogenic activities of Simendan. |
| Mexiletine | Mexiletine may increase the arrhythmogenic activities of Simendan. |
| Nisoldipine | Nisoldipine may increase the arrhythmogenic activities of Simendan. |
| Acetyldigitoxin | Acetyldigitoxin may increase the arrhythmogenic activities of Simendan. |
| Lercanidipine | Lercanidipine may increase the arrhythmogenic activities of Simendan. |
| Magnesium sulfate | Magnesium sulfate may increase the arrhythmogenic activities of Simendan. |
| Alprenolol | Alprenolol may increase the arrhythmogenic activities of Simendan. |
| Tocainide | Tocainide may increase the arrhythmogenic activities of Simendan. |
| Deslanoside | Deslanoside may increase the arrhythmogenic activities of Simendan. |
| Carvedilol | Carvedilol may increase the arrhythmogenic activities of Simendan. |
| Nadolol | Nadolol may increase the arrhythmogenic activities of Simendan. |
| Practolol | Practolol may increase the arrhythmogenic activities of Simendan. |
| Aprindine | Aprindine may increase the arrhythmogenic activities of Simendan. |
| Dexpropranolol | Dexpropranolol may increase the arrhythmogenic activities of Simendan. |
| Nimesulide | Nimesulide may increase the arrhythmogenic activities of Simendan. |
| Cyclandelate | Cyclandelate may increase the arrhythmogenic activities of Simendan. |
| Flunarizine | Flunarizine may increase the arrhythmogenic activities of Simendan. |
| Nebivolol | Nebivolol may increase the arrhythmogenic activities of Simendan. |
| Clevidipine | Clevidipine may increase the arrhythmogenic activities of Simendan. |
| Seletracetam | Seletracetam may increase the arrhythmogenic activities of Simendan. |
| Nylidrin | Nylidrin may increase the arrhythmogenic activities of Simendan. |
| Dotarizine | Dotarizine may increase the arrhythmogenic activities of Simendan. |
| Xylometazoline | Xylometazoline may increase the arrhythmogenic activities of Simendan. |
| Sparteine | Sparteine may increase the arrhythmogenic activities of Simendan. |
| Tranilast | Tranilast may increase the arrhythmogenic activities of Simendan. |
| Fasudil | Fasudil may increase the arrhythmogenic activities of Simendan. |
| Agmatine | Agmatine may increase the arrhythmogenic activities of Simendan. |
| Nicorandil | Nicorandil may increase the arrhythmogenic activities of Simendan. |
| Barnidipine | Barnidipine may increase the arrhythmogenic activities of Simendan. |
| Azelnidipine | Azelnidipine may increase the arrhythmogenic activities of Simendan. |
| Cilnidipine | Cilnidipine may increase the arrhythmogenic activities of Simendan. |
| Darodipine | Darodipine may increase the arrhythmogenic activities of Simendan. |
| Manidipine | Manidipine may increase the arrhythmogenic activities of Simendan. |
| Niludipine | Niludipine may increase the arrhythmogenic activities of Simendan. |
| Tropisetron | Tropisetron may increase the arrhythmogenic activities of Simendan. |
| Carboxyamidotriazole | Carboxyamidotriazole may increase the arrhythmogenic activities of Simendan. |
| Naftopidil | Naftopidil may increase the arrhythmogenic activities of Simendan. |
| Vinpocetine | Vinpocetine may increase the arrhythmogenic activities of Simendan. |
| Landiolol | Landiolol may increase the arrhythmogenic activities of Simendan. |
| Carteolol | Simendan may increase the arrhythmogenic activities of Carteolol. |
| Metipranolol | Simendan may increase the arrhythmogenic activities of Metipranolol. |
| Spiradoline | Simendan may increase the arrhythmogenic activities of Spiradoline. |
| Cymarin | Simendan may increase the arrhythmogenic activities of Cymarin. |
| Metildigoxin | Simendan may increase the arrhythmogenic activities of Metildigoxin. |
| Tiracizine | Simendan may increase the arrhythmogenic activities of Tiracizine. |
| Ethacizine | Simendan may increase the arrhythmogenic activities of Ethacizine. |
| Hydroquinine | Simendan may increase the arrhythmogenic activities of Hydroquinine. |
| Bioallethrin | Simendan may increase the arrhythmogenic activities of Bioallethrin. |
| Tertatolol | Simendan may increase the arrhythmogenic activities of Tertatolol. |
| Caroverine | Simendan may increase the arrhythmogenic activities of Caroverine. |
| Fosfructose | Simendan may increase the arrhythmogenic activities of Fosfructose. |
| WIN 55212-2 | Simendan may increase the arrhythmogenic activities of WIN 55212-2. |
| Fish oil | Simendan may increase the arrhythmogenic activities of Fish oil. |
| Emopamil | Simendan may increase the arrhythmogenic activities of Emopamil. |
| Lomerizine | Simendan may increase the arrhythmogenic activities of Lomerizine. |
| Tetrandrine | Simendan may increase the arrhythmogenic activities of Tetrandrine. |
| Dexniguldipine | Simendan may increase the arrhythmogenic activities of Dexniguldipine. |
| Fosinoprilat | Simendan may increase the arrhythmogenic activities of Fosinoprilat. |
| Hydroquinidine | Simendan may increase the arrhythmogenic activities of Hydroquinidine. |
| SOR-C13 | Simendan may increase the arrhythmogenic activities of SOR-C13. |
| Dofetilide | Dofetilide may increase the arrhythmogenic activities of Simendan. |
| Disopyramide | Disopyramide may increase the arrhythmogenic activities of Simendan. |
| Ibutilide | Ibutilide may increase the arrhythmogenic activities of Simendan. |
| Sotalol | Sotalol may increase the arrhythmogenic activities of Simendan. |
| Quinidine | Quinidine may increase the arrhythmogenic activities of Simendan. |
| Procainamide | Procainamide may increase the arrhythmogenic activities of Simendan. |
| Bepridil | Bepridil may increase the arrhythmogenic activities of Simendan. |
| Dronedarone | Dronedarone may increase the arrhythmogenic activities of Simendan. |
| Terodiline | Simendan may increase the arrhythmogenic activities of Terodiline. |
| Betaxolol | Betaxolol may increase the arrhythmogenic activities of Simendan. |
| Diltiazem | Diltiazem may increase the arrhythmogenic activities of Simendan. |
| Nimodipine | Nimodipine may increase the arrhythmogenic activities of Simendan. |
| Cinnarizine | Cinnarizine may increase the arrhythmogenic activities of Simendan. |
| Propranolol | Propranolol may increase the arrhythmogenic activities of Simendan. |
| Atropine | Atropine may increase the arrhythmogenic activities of Simendan. |
| Adenosine | Adenosine may increase the arrhythmogenic activities of Simendan. |
| Loperamide | Loperamide may increase the arrhythmogenic activities of Simendan. |
| Nifedipine | Nifedipine may increase the arrhythmogenic activities of Simendan. |
| Propafenone | Propafenone may increase the arrhythmogenic activities of Simendan. |
| Acebutolol | Acebutolol may increase the arrhythmogenic activities of Simendan. |
| Flecainide | Flecainide may increase the arrhythmogenic activities of Simendan. |
| Mibefradil | Mibefradil may increase the arrhythmogenic activities of Simendan. |
| Oxprenolol | Oxprenolol may increase the arrhythmogenic activities of Simendan. |
| Prenylamine | Prenylamine may increase the arrhythmogenic activities of Simendan. |
| Fluspirilene | Fluspirilene may increase the arrhythmogenic activities of Simendan. |
| Azimilide | Azimilide may increase the arrhythmogenic activities of Simendan. |
| Tedisamil | Tedisamil may increase the arrhythmogenic activities of Simendan. |
| Nilvadipine | Nilvadipine may increase the arrhythmogenic activities of Simendan. |
| Fendiline | Fendiline may increase the arrhythmogenic activities of Simendan. |
| Eperisone | Eperisone may increase the arrhythmogenic activities of Simendan. |
| Melperone | Melperone may increase the arrhythmogenic activities of Simendan. |
| Benidipine | Benidipine may increase the arrhythmogenic activities of Simendan. |
| Otilonium | Simendan may increase the arrhythmogenic activities of Otilonium. |
| Nizofenone | Simendan may increase the arrhythmogenic activities of Nizofenone. |
| Bunaftine | Simendan may increase the arrhythmogenic activities of Bunaftine. |
| Lorcainide | Simendan may increase the arrhythmogenic activities of Lorcainide. |
| Penfluridol | Simendan may increase the arrhythmogenic activities of Penfluridol. |