Cerlapirdine

DB12229

small molecule investigational

Deskripsi

Cerlapirdine has been investigated for the treatment of Alzheimer Disease.

Struktur Molekul 2D

Berat 409.5
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

677 Data
Buprenorphine Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Hydrocodone Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Magnesium sulfate The therapeutic efficacy of Cerlapirdine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Cerlapirdine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Mirtazapine Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Orphenadrine Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Pramipexole Cerlapirdine may increase the sedative activities of Pramipexole.
Ropinirole Cerlapirdine may increase the sedative activities of Ropinirole.
Rotigotine Cerlapirdine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Cerlapirdine.
Sodium oxybate Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Thalidomide Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Cerlapirdine.
Dicoumarol The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with (S)-Warfarin.
Ethanol Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Cerlapirdine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Fluvoxamine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Alaproclate.
Zopiclone The risk or severity of adverse effects can be increased when Cerlapirdine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Cerlapirdine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Cerlapirdine.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Cerlapirdine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cerlapirdine.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Cerlapirdine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Cerlapirdine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Cerlapirdine.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Cerlapirdine.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Cerlapirdine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Cerlapirdine.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Cerlapirdine.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Cerlapirdine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Cerlapirdine.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Cerlapirdine.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Cerlapirdine.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Cerlapirdine.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Cerlapirdine.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Cerlapirdine.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Cerlapirdine.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Cerlapirdine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Cerlapirdine.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Cerlapirdine.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Cerlapirdine.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Cerlapirdine.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Cerlapirdine.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Cerlapirdine.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Cerlapirdine.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Cerlapirdine.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Cerlapirdine.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Cerlapirdine.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Cerlapirdine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Cerlapirdine.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Cerlapirdine.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Cerlapirdine.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Cerlapirdine.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Cerlapirdine.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Cerlapirdine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Cerlapirdine.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Cerlapirdine.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Cerlapirdine.

Target Protein

5-hydroxytryptamine receptor 6 HTR6

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

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