Eplivanserin

DB12177

small molecule investigational

Deskripsi

Eplivanserin has been used in trials studying the treatment of Sleep, Insomnia, Chronic Pain, Fibromyalgia, and Primary Insomnia, among others.

Struktur Molekul 2D

Berat 328.387
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

677 Data
Buprenorphine Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Hydrocodone Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Magnesium sulfate The therapeutic efficacy of Eplivanserin can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Eplivanserin may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Mirtazapine Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Orphenadrine Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Pramipexole Eplivanserin may increase the sedative activities of Pramipexole.
Ropinirole Eplivanserin may increase the sedative activities of Ropinirole.
Rotigotine Eplivanserin may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Eplivanserin.
Sodium oxybate Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Thalidomide Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Eplivanserin.
Dicoumarol The risk or severity of adverse effects can be increased when Eplivanserin is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Eplivanserin is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Eplivanserin is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Eplivanserin is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Eplivanserin is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Eplivanserin is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Eplivanserin is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Eplivanserin is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Eplivanserin is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Eplivanserin is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Eplivanserin is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Eplivanserin is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Eplivanserin is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Eplivanserin is combined with (S)-Warfarin.
Ethanol Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Eplivanserin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Fluvoxamine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Eplivanserin is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Eplivanserin is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Eplivanserin is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Eplivanserin is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Eplivanserin is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Eplivanserin is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Eplivanserin is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Eplivanserin is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Eplivanserin is combined with Alaproclate.
Zopiclone The risk or severity of adverse effects can be increased when Eplivanserin is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Eplivanserin.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Eplivanserin.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Eplivanserin.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Eplivanserin.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Eplivanserin.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Eplivanserin.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Eplivanserin.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Eplivanserin.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Eplivanserin.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Eplivanserin.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Eplivanserin.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Eplivanserin.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Eplivanserin.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Eplivanserin.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Eplivanserin.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Eplivanserin.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Eplivanserin.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Eplivanserin.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Eplivanserin.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Eplivanserin.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Eplivanserin.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Eplivanserin.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Eplivanserin.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Eplivanserin.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Eplivanserin.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Eplivanserin.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Eplivanserin.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Eplivanserin.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Eplivanserin.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Eplivanserin.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Eplivanserin.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Eplivanserin.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Eplivanserin.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Eplivanserin.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Eplivanserin.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Eplivanserin.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Eplivanserin.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Eplivanserin.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Eplivanserin.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Eplivanserin.

Target Protein

5-hydroxytryptamine receptor 2A HTR2A
5-hydroxytryptamine receptor 2C HTR2C

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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