Simtuzumab

DB12152

biotech investigational

Deskripsi

Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

373 Data
Diethylstilbestrol Diethylstilbestrol may increase the thrombogenic activities of Simtuzumab.
Chlorotrianisene Chlorotrianisene may increase the thrombogenic activities of Simtuzumab.
Conjugated estrogens Conjugated estrogens may increase the thrombogenic activities of Simtuzumab.
Estrone Estrone may increase the thrombogenic activities of Simtuzumab.
Estradiol Estradiol may increase the thrombogenic activities of Simtuzumab.
Dienestrol Dienestrol may increase the thrombogenic activities of Simtuzumab.
Ethinylestradiol Ethinylestradiol may increase the thrombogenic activities of Simtuzumab.
Mestranol Mestranol may increase the thrombogenic activities of Simtuzumab.
Estriol Estriol may increase the thrombogenic activities of Simtuzumab.
Estrone sulfate Estrone sulfate may increase the thrombogenic activities of Simtuzumab.
Quinestrol Quinestrol may increase the thrombogenic activities of Simtuzumab.
Hexestrol Hexestrol may increase the thrombogenic activities of Simtuzumab.
Tibolone Tibolone may increase the thrombogenic activities of Simtuzumab.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may increase the thrombogenic activities of Simtuzumab.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may increase the thrombogenic activities of Simtuzumab.
Polyestradiol phosphate Polyestradiol phosphate may increase the thrombogenic activities of Simtuzumab.
Esterified estrogens Esterified estrogens may increase the thrombogenic activities of Simtuzumab.
Zeranol Zeranol may increase the thrombogenic activities of Simtuzumab.
Equol Equol may increase the thrombogenic activities of Simtuzumab.
Promestriene Promestriene may increase the thrombogenic activities of Simtuzumab.
Methallenestril Methallenestril may increase the thrombogenic activities of Simtuzumab.
Epimestrol Epimestrol may increase the thrombogenic activities of Simtuzumab.
Moxestrol Moxestrol may increase the thrombogenic activities of Simtuzumab.
Estradiol acetate Estradiol acetate may increase the thrombogenic activities of Simtuzumab.
Estradiol benzoate Estradiol benzoate may increase the thrombogenic activities of Simtuzumab.
Estradiol cypionate Estradiol cypionate may increase the thrombogenic activities of Simtuzumab.
Estradiol valerate Estradiol valerate may increase the thrombogenic activities of Simtuzumab.
Biochanin A Biochanin A may increase the thrombogenic activities of Simtuzumab.
Formononetin Formononetin may increase the thrombogenic activities of Simtuzumab.
Estetrol Estetrol may increase the thrombogenic activities of Simtuzumab.
Cetuximab The risk or severity of adverse effects can be increased when Cetuximab is combined with Simtuzumab.
Human immunoglobulin G The risk or severity of adverse effects can be increased when Human immunoglobulin G is combined with Simtuzumab.
Omalizumab The risk or severity of adverse effects can be increased when Omalizumab is combined with Simtuzumab.
Adalimumab The risk or severity of adverse effects can be increased when Adalimumab is combined with Simtuzumab.
Abciximab The risk or severity of adverse effects can be increased when Abciximab is combined with Simtuzumab.
Gemtuzumab ozogamicin The risk or severity of adverse effects can be increased when Gemtuzumab ozogamicin is combined with Simtuzumab.
Indium In-111 satumomab pendetide The risk or severity of adverse effects can be increased when Indium In-111 satumomab pendetide is combined with Simtuzumab.
Infliximab The risk or severity of adverse effects can be increased when Infliximab is combined with Simtuzumab.
Trastuzumab The risk or severity of adverse effects can be increased when Trastuzumab is combined with Simtuzumab.
Rituximab The risk or severity of adverse effects can be increased when Rituximab is combined with Simtuzumab.
Basiliximab The risk or severity of adverse effects can be increased when Basiliximab is combined with Simtuzumab.
Muromonab The risk or severity of adverse effects can be increased when Muromonab is combined with Simtuzumab.
Digoxin Immune Fab (Ovine) The risk or severity of adverse effects can be increased when Digoxin Immune Fab (Ovine) is combined with Simtuzumab.
Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Ibritumomab tiuxetan is combined with Simtuzumab.
Tositumomab The risk or severity of adverse effects can be increased when Tositumomab is combined with Simtuzumab.
Alemtuzumab The risk or severity of adverse effects can be increased when Alemtuzumab is combined with Simtuzumab.
Capromab pendetide The risk or severity of adverse effects can be increased when Capromab pendetide is combined with Simtuzumab.
Efalizumab The risk or severity of adverse effects can be increased when Efalizumab is combined with Simtuzumab.
Antithymocyte immunoglobulin (rabbit) The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Simtuzumab.
Natalizumab The risk or severity of adverse effects can be increased when Natalizumab is combined with Simtuzumab.
Palivizumab The risk or severity of adverse effects can be increased when Palivizumab is combined with Simtuzumab.
Daclizumab The risk or severity of adverse effects can be increased when Daclizumab is combined with Simtuzumab.
Bevacizumab The risk or severity of adverse effects can be increased when Bevacizumab is combined with Simtuzumab.
Technetium Tc-99m arcitumomab The risk or severity of adverse effects can be increased when Technetium Tc-99m arcitumomab is combined with Simtuzumab.
Eculizumab The risk or severity of adverse effects can be increased when Eculizumab is combined with Simtuzumab.
Panitumumab The risk or severity of adverse effects can be increased when Panitumumab is combined with Simtuzumab.
Ranibizumab The risk or severity of adverse effects can be increased when Ranibizumab is combined with Simtuzumab.
Galiximab The risk or severity of adverse effects can be increased when Galiximab is combined with Simtuzumab.
Pexelizumab The risk or severity of adverse effects can be increased when Pexelizumab is combined with Simtuzumab.
Afelimomab The risk or severity of adverse effects can be increased when Afelimomab is combined with Simtuzumab.
Epratuzumab The risk or severity of adverse effects can be increased when Epratuzumab is combined with Simtuzumab.
Bectumomab The risk or severity of adverse effects can be increased when Bectumomab is combined with Simtuzumab.
Oregovomab The risk or severity of adverse effects can be increased when Oregovomab is combined with Simtuzumab.
IGN311 The risk or severity of adverse effects can be increased when IGN311 is combined with Simtuzumab.
Adecatumumab The risk or severity of adverse effects can be increased when Adecatumumab is combined with Simtuzumab.
Labetuzumab The risk or severity of adverse effects can be increased when Labetuzumab is combined with Simtuzumab.
Matuzumab The risk or severity of adverse effects can be increased when Matuzumab is combined with Simtuzumab.
Fontolizumab The risk or severity of adverse effects can be increased when Fontolizumab is combined with Simtuzumab.
Bavituximab The risk or severity of adverse effects can be increased when Bavituximab is combined with Simtuzumab.
CR002 The risk or severity of adverse effects can be increased when CR002 is combined with Simtuzumab.
Rozrolimupab The risk or severity of adverse effects can be increased when Rozrolimupab is combined with Simtuzumab.
Girentuximab The risk or severity of adverse effects can be increased when Girentuximab is combined with Simtuzumab.
Obiltoxaximab The risk or severity of adverse effects can be increased when Obiltoxaximab is combined with Simtuzumab.
XTL-001 The risk or severity of adverse effects can be increased when XTL-001 is combined with Simtuzumab.
NAV 1800 The risk or severity of adverse effects can be increased when NAV 1800 is combined with Simtuzumab.
Briakinumab The risk or severity of adverse effects can be increased when Briakinumab is combined with Simtuzumab.
Otelixizumab The risk or severity of adverse effects can be increased when Otelixizumab is combined with Simtuzumab.
AMG 108 The risk or severity of adverse effects can be increased when AMG 108 is combined with Simtuzumab.
Iratumumab The risk or severity of adverse effects can be increased when Iratumumab is combined with Simtuzumab.
Enokizumab The risk or severity of adverse effects can be increased when Enokizumab is combined with Simtuzumab.
Ramucirumab The risk or severity of adverse effects can be increased when Ramucirumab is combined with Simtuzumab.
Farletuzumab The risk or severity of adverse effects can be increased when Farletuzumab is combined with Simtuzumab.
Veltuzumab The risk or severity of adverse effects can be increased when Veltuzumab is combined with Simtuzumab.
Ustekinumab The risk or severity of adverse effects can be increased when Ustekinumab is combined with Simtuzumab.
Trastuzumab emtansine The risk or severity of adverse effects can be increased when Trastuzumab emtansine is combined with Simtuzumab.
PRO-542 The risk or severity of adverse effects can be increased when PRO-542 is combined with Simtuzumab.
TNX-901 The risk or severity of adverse effects can be increased when TNX-901 is combined with Simtuzumab.
Inotuzumab ozogamicin The risk or severity of adverse effects can be increased when Inotuzumab ozogamicin is combined with Simtuzumab.
RI 624 The risk or severity of adverse effects can be increased when RI 624 is combined with Simtuzumab.
Stamulumab The risk or severity of adverse effects can be increased when MYO-029 is combined with Simtuzumab.
CT-011 The risk or severity of adverse effects can be increased when CT-011 is combined with Simtuzumab.
Leronlimab The risk or severity of adverse effects can be increased when Leronlimab is combined with Simtuzumab.
Glembatumumab vedotin The risk or severity of adverse effects can be increased when Glembatumumab vedotin is combined with Simtuzumab.
Olaratumab The risk or severity of adverse effects can be increased when Olaratumab is combined with Simtuzumab.
IPH 2101 The risk or severity of adverse effects can be increased when IPH 2101 is combined with Simtuzumab.
TB-402 The risk or severity of adverse effects can be increased when TB-402 is combined with Simtuzumab.
Caplacizumab The risk or severity of adverse effects can be increased when Caplacizumab is combined with Simtuzumab.
IMC-1C11 The risk or severity of adverse effects can be increased when IMC-1C11 is combined with Simtuzumab.
Eldelumab The risk or severity of adverse effects can be increased when Eldelumab is combined with Simtuzumab.
Lumiliximab The risk or severity of adverse effects can be increased when Lumiliximab is combined with Simtuzumab.

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