Vabicaserin

DB12071

small molecule investigational

Deskripsi

Vabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.

Struktur Molekul 2D

Berat 228.339
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

703 Data
Buprenorphine Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Hydrocodone Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Magnesium sulfate The therapeutic efficacy of Vabicaserin can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Vabicaserin may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Orphenadrine Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Pramipexole Vabicaserin may increase the sedative activities of Pramipexole.
Ropinirole Vabicaserin may increase the sedative activities of Ropinirole.
Rotigotine Vabicaserin may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Vabicaserin.
Sodium oxybate Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Thalidomide Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Vabicaserin.
Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Vabicaserin.
Dicoumarol The risk or severity of adverse effects can be increased when Vabicaserin is combined with Dicoumarol.
Phenindione The risk or severity of adverse effects can be increased when Vabicaserin is combined with Phenindione.
Warfarin The risk or severity of adverse effects can be increased when Vabicaserin is combined with Warfarin.
Phenprocoumon The risk or severity of adverse effects can be increased when Vabicaserin is combined with Phenprocoumon.
Acenocoumarol The risk or severity of adverse effects can be increased when Vabicaserin is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of adverse effects can be increased when Vabicaserin is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of adverse effects can be increased when Vabicaserin is combined with Coumarin.
(R)-warfarin The risk or severity of adverse effects can be increased when Vabicaserin is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of adverse effects can be increased when Vabicaserin is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of adverse effects can be increased when Vabicaserin is combined with Fluindione.
Clorindione The risk or severity of adverse effects can be increased when Vabicaserin is combined with Clorindione.
Diphenadione The risk or severity of adverse effects can be increased when Vabicaserin is combined with Diphenadione.
Tioclomarol The risk or severity of adverse effects can be increased when Vabicaserin is combined with Tioclomarol.
(S)-Warfarin The risk or severity of adverse effects can be increased when Vabicaserin is combined with (S)-Warfarin.
Mirtazapine Vabicaserin may increase the serotonergic activities of Mirtazapine.
Ethanol Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Vabicaserin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Fluvoxamine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Vabicaserin is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Duloxetine.
Paroxetine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Vabicaserin is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Vabicaserin is combined with Nefazodone.
Zimelidine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Vabicaserin is combined with Milnacipran.
Desvenlafaxine The risk or severity of serotonin syndrome can be increased when Desvenlafaxine is combined with Vabicaserin.
Seproxetine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Seproxetine.
Levomilnacipran The risk or severity of serotonin syndrome can be increased when Vabicaserin is combined with Levomilnacipran.
Indalpine The risk or severity of adverse effects can be increased when Vabicaserin is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Vabicaserin is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Vabicaserin is combined with Alaproclate.
Methylene blue Vabicaserin may increase the serotonergic activities of Methylene blue.
Zopiclone The risk or severity of adverse effects can be increased when Vabicaserin is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Vabicaserin.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Vabicaserin.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Vabicaserin.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Vabicaserin.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Vabicaserin.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Vabicaserin.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Vabicaserin.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Vabicaserin.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Vabicaserin.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Vabicaserin.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Vabicaserin.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Vabicaserin.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Vabicaserin.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Vabicaserin.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Vabicaserin.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Vabicaserin.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Vabicaserin.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Vabicaserin.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Vabicaserin.
Venlafaxine The risk or severity of serotonin syndrome can be increased when Vabicaserin is combined with Venlafaxine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Vabicaserin.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Vabicaserin.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Vabicaserin.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Vabicaserin.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Vabicaserin.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Vabicaserin.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Vabicaserin.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Vabicaserin.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Vabicaserin.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Vabicaserin.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Vabicaserin.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Vabicaserin.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Vabicaserin.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Vabicaserin.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Vabicaserin.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Vabicaserin.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Vabicaserin.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Vabicaserin.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Vabicaserin.

Target Protein

5-hydroxytryptamine receptor 2B HTR2B
5-hydroxytryptamine receptor 2C HTR2C

Referensi & Sumber

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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