2,4-thiazolidinedione

DB11898

small molecule investigational

Deskripsi

Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.

Struktur Molekul 2D

Berat 117.12
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

602 Data
Pegvisomant The risk or severity of hypoglycemia can be increased when Pegvisomant is combined with 2,4-thiazolidinedione.
Lipoic acid The risk or severity of hypoglycemia can be increased when Lipoic acid is combined with 2,4-thiazolidinedione.
Moxifloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Moxifloxacin.
Grepafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Grepafloxacin.
Enoxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Enoxacin.
Pefloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Pefloxacin.
Ciprofloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Ciprofloxacin.
Trovafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Trovafloxacin.
Nalidixic acid The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Nalidixic acid.
Rosoxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Rosoxacin.
Cinoxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Cinoxacin.
Lomefloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Lomefloxacin.
Gatifloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Gatifloxacin.
Norfloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Norfloxacin.
Levofloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Levofloxacin.
Gemifloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Gemifloxacin.
Ofloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Ofloxacin.
Sparfloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sparfloxacin.
Temafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Temafloxacin.
Fleroxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Fleroxacin.
Technetium Tc-99m ciprofloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Technetium Tc-99m ciprofloxacin.
Garenoxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Garenoxacin.
Nemonoxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Nemonoxacin.
Flumequine The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Flumequine.
Enrofloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Enrofloxacin.
Orbifloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Orbifloxacin.
Sarafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sarafloxacin.
Difloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Difloxacin.
Pazufloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Pazufloxacin.
Prulifloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Prulifloxacin.
Delafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Delafloxacin.
Sitafloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sitafloxacin.
Oxolinic acid The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Oxolinic acid.
Rufloxacin The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Rufloxacin.
Pipemidic acid The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Pipemidic acid.
Methyclothiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Methyclothiazide.
Chlorthalidone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Chlorthalidone.
Bendroflumethiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Bendroflumethiazide.
Metolazone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Metolazone.
Benzthiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Benzthiazide.
Hydroflumethiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Hydroflumethiazide.
Indapamide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Indapamide.
Chlorothiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Chlorothiazide.
Hydrochlorothiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Hydrochlorothiazide.
Trichlormethiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Trichlormethiazide.
Polythiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Polythiazide.
Quinethazone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Quinethazone.
Cyclopenthiazide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Cyclopenthiazide.
Epitizide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Epitizide.
Amitriptyline Amitriptyline may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Protriptyline Protriptyline may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Imipramine Imipramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Nortriptyline Nortriptyline may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Amoxapine Amoxapine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Trimipramine Trimipramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Doxepin Doxepin may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Desipramine Desipramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Clomipramine Clomipramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Amineptine Amineptine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Dimetacrine Dimetacrine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Butriptyline Butriptyline may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Dosulepin Dosulepin may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Tianeptine Tianeptine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Oxaprotiline Oxaprotiline may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Opipramol Opipramol may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Amitriptylinoxide Amitriptylinoxide may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Dibenzepin Dibenzepin may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Quinupramine Quinupramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Melitracen Melitracen may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Lofepramine Lofepramine may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Iprindole Iprindole may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Imipramine oxide Imipramine oxide may decrease the hypoglycemic activities of 2,4-thiazolidinedione.
Dapagliflozin Dapagliflozin may increase the hypoglycemic activities of 2,4-thiazolidinedione.
Canagliflozin Canagliflozin may increase the hypoglycemic activities of 2,4-thiazolidinedione.
Leuprolide The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Leuprolide.
Goserelin The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Goserelin.
Nelfinavir The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Nelfinavir.
Indinavir The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Indinavir.
Ziprasidone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Ziprasidone.
Etonogestrel The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Etonogestrel.
Desogestrel The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Desogestrel.
Olanzapine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Olanzapine.
Megestrol acetate The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Megestrol acetate.
Clozapine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Clozapine.
Levonorgestrel The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Levonorgestrel.
Progesterone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Progesterone.
Chlorpromazine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Chlorpromazine.
Haloperidol The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Haloperidol.
Ritonavir The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Ritonavir.
Piperazine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Piperazine.
Medroxyprogesterone acetate The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Medroxyprogesterone acetate.
Niacin The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Niacin.
Epinephrine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Epinephrine.
Norethisterone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Norethisterone.
Risperidone The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Risperidone.
Pentamidine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Pentamidine.
Ethynodiol diacetate The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Ethynodiol diacetate.
Pseudoephedrine The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Pseudoephedrine.
Tacrolimus The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Tacrolimus.
Sirolimus The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Sirolimus.

Target Protein

Peroxisome proliferator-activated receptor gamma PPARG

Referensi & Sumber

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Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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