Valspodar

DB11869

small molecule investigational

Deskripsi

Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others.

Struktur Molekul 2D

Berat 1214.646
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

288 Data
Afatinib The serum concentration of Afatinib can be increased when it is combined with Valspodar.
Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Valspodar.
Brentuximab vedotin The serum concentration of Brentuximab vedotin can be increased when it is combined with Valspodar.
Colchicine The serum concentration of Colchicine can be increased when it is combined with Valspodar.
Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Valspodar.
Ledipasvir The serum concentration of Ledipasvir can be increased when it is combined with Valspodar.
Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Valspodar.
Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Valspodar.
Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Valspodar.
Ranolazine The serum concentration of Ranolazine can be increased when it is combined with Valspodar.
Silodosin The excretion of Silodosin can be decreased when combined with Valspodar.
Topotecan The serum concentration of Topotecan can be increased when it is combined with Valspodar.
Everolimus The serum concentration of Everolimus can be increased when it is combined with Valspodar.
Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Valspodar.
Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Valspodar.
Vincristine The excretion of Vincristine can be decreased when combined with Valspodar.
Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Valspodar.
Lumacaftor The serum concentration of Valspodar can be decreased when it is combined with Lumacaftor.
Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Valspodar.
Vemurafenib The serum concentration of Valspodar can be increased when it is combined with Vemurafenib.
Apalutamide The serum concentration of Valspodar can be decreased when it is combined with Apalutamide.
Pitolisant The serum concentration of Valspodar can be increased when it is combined with Pitolisant.
Isavuconazole The serum concentration of Valspodar can be increased when it is combined with Isavuconazole.
Isavuconazonium The serum concentration of Valspodar can be increased when it is combined with Isavuconazonium.
Fluconazole The serum concentration of Valspodar can be increased when it is combined with Fluconazole.
Erythromycin The serum concentration of Valspodar can be increased when it is combined with Erythromycin.
Sildenafil The serum concentration of Valspodar can be increased when it is combined with Sildenafil.
Reserpine The serum concentration of Valspodar can be increased when it is combined with Reserpine.
Tenofovir disoproxil The serum concentration of Tenofovir disoproxil can be increased when it is combined with Valspodar.
Sorafenib The serum concentration of Valspodar can be increased when it is combined with Sorafenib.
Loxapine The serum concentration of Valspodar can be increased when it is combined with Loxapine.
Quinine The serum concentration of Valspodar can be increased when it is combined with Quinine.
Ritonavir The serum concentration of Valspodar can be increased when it is combined with Ritonavir.
Toremifene The serum concentration of Valspodar can be increased when it is combined with Toremifene.
Simvastatin The serum concentration of Valspodar can be increased when it is combined with Simvastatin.
Verapamil The serum concentration of Valspodar can be increased when it is combined with Verapamil.
Tamoxifen The serum concentration of Valspodar can be increased when it is combined with Tamoxifen.
Mifepristone The serum concentration of Valspodar can be increased when it is combined with Mifepristone.
Loperamide The excretion of Loperamide can be decreased when combined with Valspodar.
Vardenafil The serum concentration of Valspodar can be increased when it is combined with Vardenafil.
Conivaptan The serum concentration of Valspodar can be increased when it is combined with Conivaptan.
Zonisamide The serum concentration of Valspodar can be increased when it is combined with Zonisamide.
Tipranavir The serum concentration of Valspodar can be increased when it is combined with Tipranavir.
Fexofenadine The serum concentration of Fexofenadine can be increased when it is combined with Valspodar.
Ketoconazole The serum concentration of Valspodar can be increased when it is combined with Ketoconazole.
Amiodarone The serum concentration of Valspodar can be increased when it is combined with Amiodarone.
Carvedilol The serum concentration of Valspodar can be increased when it is combined with Carvedilol.
Itraconazole The serum concentration of Valspodar can be increased when it is combined with Itraconazole.
Propafenone The serum concentration of Valspodar can be increased when it is combined with Propafenone.
Clarithromycin The serum concentration of Valspodar can be increased when it is combined with Clarithromycin.
Saquinavir The serum concentration of Valspodar can be increased when it is combined with Saquinavir.
Lapatinib The serum concentration of Valspodar can be increased when it is combined with Lapatinib.
Posaconazole The serum concentration of Posaconazole can be increased when it is combined with Valspodar.
Paliperidone The serum concentration of Valspodar can be increased when it is combined with Paliperidone.
Mibefradil The serum concentration of Valspodar can be increased when it is combined with Mibefradil.
Lopinavir The serum concentration of Valspodar can be increased when it is combined with Lopinavir.
Biricodar The serum concentration of Valspodar can be increased when it is combined with Biricodar.
Dronedarone The serum concentration of Valspodar can be increased when it is combined with Dronedarone.
Nilotinib The serum concentration of Valspodar can be increased when it is combined with Nilotinib.
Elacridar The serum concentration of Valspodar can be increased when it is combined with Elacridar.
Flibanserin The serum concentration of Valspodar can be increased when it is combined with Flibanserin.
Vandetanib The serum concentration of Valspodar can be increased when it is combined with Vandetanib.
Telaprevir The serum concentration of Valspodar can be increased when it is combined with Telaprevir.
Zosuquidar The serum concentration of Valspodar can be increased when it is combined with Zosuquidar.
Tariquidar The serum concentration of Valspodar can be increased when it is combined with Tariquidar.
Simeprevir The serum concentration of Valspodar can be increased when it is combined with Simeprevir.
Brefeldin A The serum concentration of Valspodar can be increased when it is combined with Brefeldin A.
Ticagrelor The serum concentration of Valspodar can be increased when it is combined with Ticagrelor.
Ivacaftor The serum concentration of Valspodar can be increased when it is combined with Ivacaftor.
Lomitapide The serum concentration of Valspodar can be increased when it is combined with Lomitapide.
Linagliptin The serum concentration of Valspodar can be increased when it is combined with Linagliptin.
Mirabegron The serum concentration of Valspodar can be increased when it is combined with Mirabegron.
Ponatinib The serum concentration of Valspodar can be increased when it is combined with Ponatinib.
Canagliflozin The serum concentration of Valspodar can be increased when it is combined with Canagliflozin.
Vorapaxar The serum concentration of Valspodar can be increased when it is combined with Vorapaxar.
Suvorexant The serum concentration of Valspodar can be increased when it is combined with Suvorexant.
Eliglustat The serum concentration of Valspodar can be increased when it is combined with Eliglustat.
Netupitant The serum concentration of Valspodar can be increased when it is combined with Netupitant.
Idelalisib The serum concentration of Idelalisib can be increased when it is combined with Valspodar.
Cobicistat The serum concentration of Valspodar can be increased when it is combined with Cobicistat.
Palbociclib The serum concentration of Valspodar can be increased when it is combined with Palbociclib.
Daclatasvir The serum concentration of Valspodar can be increased when it is combined with Daclatasvir.
Niguldipine The serum concentration of Valspodar can be increased when it is combined with Niguldipine.
Rolapitant The serum concentration of Valspodar can be increased when it is combined with Rolapitant.
Paritaprevir The serum concentration of Paritaprevir can be increased when it is combined with Valspodar.
Asunaprevir The serum concentration of Valspodar can be increased when it is combined with Asunaprevir.
Velpatasvir The serum concentration of Valspodar can be increased when it is combined with Velpatasvir.
Tezacaftor The serum concentration of Tezacaftor can be increased when it is combined with Valspodar.
Neratinib The serum concentration of Valspodar can be increased when it is combined with Neratinib.
Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Valspodar.
Morphine The serum concentration of Morphine can be increased when it is combined with Valspodar.
Clobazam The serum concentration of Clobazam can be increased when it is combined with Valspodar.
Mannitol The serum concentration of Mannitol can be increased when it is combined with Valspodar.
Clomifene The serum concentration of Clomifene can be increased when it is combined with Valspodar.
Tegaserod The serum concentration of Tegaserod can be increased when it is combined with Valspodar.
Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Valspodar.
Belinostat The serum concentration of Belinostat can be increased when it is combined with Valspodar.
Indacaterol The serum concentration of Indacaterol can be increased when it is combined with Valspodar.
Rivaroxaban The serum concentration of Rivaroxaban can be increased when it is combined with Valspodar.
Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Valspodar.

Target Protein

Coagulation factor X F10

Referensi & Sumber

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