Pazufloxacin

DB11774

small molecule investigational

Deskripsi

Pazufloxacin is under investigation in clinical trial NCT02592096 (Pazufloxacin Mesilate Ear Drops Clinical Trial Protocol).

Struktur Molekul 2D

Berat 318.304
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

936 Data
Didanosine Didanosine can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Pazufloxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Pazufloxacin.
Nitrofurantoin The therapeutic efficacy of Pazufloxacin can be decreased when used in combination with Nitrofurantoin.
Agomelatine The serum concentration of Agomelatine can be increased when it is combined with Pazufloxacin.
Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Pazufloxacin.
Tizanidine The serum concentration of Tizanidine can be increased when it is combined with Pazufloxacin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Pazufloxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Pazufloxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Pazufloxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Pazufloxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Pazufloxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Pazufloxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Pazufloxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Pazufloxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Pazufloxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Pazufloxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Pazufloxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Pazufloxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Pazufloxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Pazufloxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Pazufloxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Pazufloxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Pazufloxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Pazufloxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Pazufloxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Pazufloxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Pazufloxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Pazufloxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Pazufloxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Pazufloxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Pazufloxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Pazufloxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Pazufloxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Pazufloxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Pazufloxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Pazufloxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Pazufloxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Pazufloxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Pazufloxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Pazufloxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Pazufloxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Pazufloxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Pazufloxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Pazufloxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Pazufloxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Pazufloxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Pazufloxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Pazufloxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Pazufloxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Pazufloxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Pazufloxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Pazufloxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Pazufloxacin.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Pazufloxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Pazufloxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Pazufloxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Pazufloxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Pazufloxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Pazufloxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Pazufloxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Pazufloxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Pazufloxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Pazufloxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Pazufloxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Pazufloxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Pazufloxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Pazufloxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Pazufloxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Pazufloxacin.
Insulin beef The therapeutic efficacy of Insulin beef can be increased when used in combination with Pazufloxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Pazufloxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Pazufloxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Pazufloxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Pazufloxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Pazufloxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Pazufloxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Pazufloxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Pazufloxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Pazufloxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Pazufloxacin.

Target Protein

DNA gyrase subunit A gyrA
DNA gyrase subunit B gyrB
DNA topoisomerase 4 subunit A parC

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul