Ebastine

DB11742

small molecule approved investigational

Deskripsi

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.

Struktur Molekul 2D

Berat 469.6576
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Take with or without food. Taking ebastine with food may increase its bioavailability.

Interaksi Obat

791 Data
Phenytoin The metabolism of Ebastine can be increased when combined with Phenytoin.
Fosphenytoin The metabolism of Ebastine can be increased when combined with Fosphenytoin.
Benzylpenicilloyl polylysine Ebastine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Betahistine The therapeutic efficacy of Betahistine can be decreased when used in combination with Ebastine.
Amphetamine Amphetamine may decrease the sedative activities of Ebastine.
Phentermine Phentermine may decrease the sedative activities of Ebastine.
Pseudoephedrine Pseudoephedrine may decrease the sedative activities of Ebastine.
Benzphetamine Benzphetamine may decrease the sedative activities of Ebastine.
Diethylpropion Diethylpropion may decrease the sedative activities of Ebastine.
Lisdexamfetamine Lisdexamfetamine may decrease the sedative activities of Ebastine.
Mephentermine Mephentermine may decrease the sedative activities of Ebastine.
MMDA MMDA may decrease the sedative activities of Ebastine.
Midomafetamine Midomafetamine may decrease the sedative activities of Ebastine.
2,5-Dimethoxy-4-ethylamphetamine 2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative activities of Ebastine.
4-Bromo-2,5-dimethoxyamphetamine 4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative activities of Ebastine.
Tenamfetamine Tenamfetamine may decrease the sedative activities of Ebastine.
Chlorphentermine Chlorphentermine may decrease the sedative activities of Ebastine.
Methylenedioxyethamphetamine Methylenedioxyethamphetamine may decrease the sedative activities of Ebastine.
Dextroamphetamine Dextroamphetamine may decrease the sedative activities of Ebastine.
Metamfetamine Metamfetamine may decrease the sedative activities of Ebastine.
Iofetamine I-123 Iofetamine I-123 may decrease the sedative activities of Ebastine.
Ritobegron Ritobegron may decrease the sedative activities of Ebastine.
Mephedrone Mephedrone may decrease the sedative activities of Ebastine.
Methoxyphenamine Methoxyphenamine may decrease the sedative activities of Ebastine.
Gepefrine Gepefrine may decrease the sedative activities of Ebastine.
2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative activities of Ebastine.
Phendimetrazine Phendimetrazine may decrease the sedative activities of Ebastine.
Goserelin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Goserelin.
Moxifloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Moxifloxacin.
Sulfisoxazole The risk or severity of QTc prolongation can be increased when Ebastine is combined with Sulfisoxazole.
Sulpiride The risk or severity of QTc prolongation can be increased when Ebastine is combined with Sulpiride.
Droperidol The risk or severity of QTc prolongation can be increased when Ebastine is combined with Droperidol.
Oxaliplatin The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Ebastine.
Fluorouracil The risk or severity of QTc prolongation can be increased when Ebastine is combined with Fluorouracil.
Perflutren The risk or severity of QTc prolongation can be increased when Ebastine is combined with Perflutren.
Atropine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Atropine.
Adenosine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Adenosine.
Pentamidine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Pentamidine.
Gadobenic acid The risk or severity of QTc prolongation can be increased when Ebastine is combined with Gadobenic acid.
Nalidixic acid The risk or severity of QTc prolongation can be increased when Ebastine is combined with Nalidixic acid.
Cinoxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Cinoxacin.
Levosimendan The risk or severity of QTc prolongation can be increased when Ebastine is combined with Levosimendan.
Mesoridazine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Mesoridazine.
Desloratadine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Desloratadine.
Lomefloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Lomefloxacin.
Dimenhydrinate The risk or severity of QTc prolongation can be increased when Ebastine is combined with Dimenhydrinate.
Papaverine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Papaverine.
Gemifloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Gemifloxacin.
Ofloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Ofloxacin.
Flecainide The risk or severity of QTc prolongation can be increased when Ebastine is combined with Flecainide.
Probucol The risk or severity of QTc prolongation can be increased when Ebastine is combined with Probucol.
Aceprometazine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Aceprometazine.
Terlipressin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Terlipressin.
Lofexidine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Lofexidine.
Azimilide The risk or severity of QTc prolongation can be increased when Ebastine is combined with Azimilide.
Pracinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Pracinostat.
Technetium Tc-99m ciprofloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Technetium Tc-99m ciprofloxacin.
Garenoxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Garenoxacin.
Tedisamil The risk or severity of QTc prolongation can be increased when Ebastine is combined with Tedisamil.
Tucidinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Tucidinostat.
Telavancin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Telavancin.
Nemonoxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Nemonoxacin.
Antazoline The risk or severity of QTc prolongation can be increased when Ebastine is combined with Antazoline.
Butriptyline The risk or severity of QTc prolongation can be increased when Ebastine is combined with Butriptyline.
Melperone The risk or severity of QTc prolongation can be increased when Ebastine is combined with Melperone.
Amifampridine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Amifampridine.
Mocetinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Mocetinostat.
Entinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Entinostat.
CUDC-101 The risk or severity of QTc prolongation can be increased when Ebastine is combined with CUDC-101.
Simendan The risk or severity of QTc prolongation can be increased when Ebastine is combined with Simendan.
Ricolinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Ricolinostat.
Mizolastine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Mizolastine.
Abexinostat The risk or severity of QTc prolongation can be increased when Ebastine is combined with Abexinostat.
Oxatomide The risk or severity of QTc prolongation can be increased when Ebastine is combined with Oxatomide.
Sitafloxacin The risk or severity of QTc prolongation can be increased when Ebastine is combined with Sitafloxacin.
Sultopride The risk or severity of QTc prolongation can be increased when Ebastine is combined with Sultopride.
Nizofenone The risk or severity of QTc prolongation can be increased when Ebastine is combined with Nizofenone.
Bunaftine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Bunaftine.
Lorcainide The risk or severity of QTc prolongation can be increased when Ebastine is combined with Lorcainide.
Dexchlorpheniramine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Dexchlorpheniramine.
Carbinoxamine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Carbinoxamine.
Leuprolide The risk or severity of QTc prolongation can be increased when Ebastine is combined with Leuprolide.
Nimodipine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Nimodipine.
Promazine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Promazine.
Cinnarizine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Cinnarizine.
Chloroquine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Chloroquine.
Dolasetron The risk or severity of QTc prolongation can be increased when Ebastine is combined with Dolasetron.
Granisetron The risk or severity of QTc prolongation can be increased when Ebastine is combined with Granisetron.
Ondansetron The risk or severity of QTc prolongation can be increased when Ebastine is combined with Ondansetron.
Chlorpheniramine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Chlorpheniramine.
Propafenone The risk or severity of QTc prolongation can be increased when Ebastine is combined with Propafenone.
Quetiapine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Quetiapine.
Prenylamine The risk or severity of QTc prolongation can be increased when Ebastine is combined with Prenylamine.
Fluspirilene The risk or severity of QTc prolongation can be increased when Ebastine is combined with Fluspirilene.
Bedaquiline The risk or severity of QTc prolongation can be increased when Ebastine is combined with Bedaquiline.
Fendiline The risk or severity of QTc prolongation can be increased when Ebastine is combined with Fendiline.
Eperisone The risk or severity of QTc prolongation can be increased when Ebastine is combined with Eperisone.
Dexchlorpheniramine maleate The risk or severity of QTc prolongation can be increased when Ebastine is combined with Dexchlorpheniramine maleate.
Otilonium The risk or severity of QTc prolongation can be increased when Ebastine is combined with Otilonium.
Penfluridol The risk or severity of QTc prolongation can be increased when Ebastine is combined with Penfluridol.

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