Ilorasertib

DB11694

small molecule investigational

Deskripsi

Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.

Struktur Molekul 2D

Berat 488.54
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

39 Data
Darbepoetin alfa The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Ilorasertib.
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Ilorasertib.
Peginesatide The risk or severity of Thrombosis can be increased when Peginesatide is combined with Ilorasertib.
Methoxy polyethylene glycol-epoetin beta The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Ilorasertib.
Lidocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Quinisocaine.
Nelarabine The risk or severity of adverse effects can be increased when Nelarabine is combined with Ilorasertib.
Ambroxol The risk or severity of methemoglobinemia can be increased when Ilorasertib is combined with Ambroxol.
Etrasimod The risk or severity of immunosuppression can be increased when Ilorasertib is combined with Etrasimod.

Target Protein

Aurora kinase A AURKA
Aurora kinase B AURKB
Aurora kinase C AURKC

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
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Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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