Dactolisib

DB11651

small molecule investigational

Deskripsi

Dactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.

Struktur Molekul 2D

Berat 469.548
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

39 Data
Darbepoetin alfa The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Dactolisib.
Erythropoietin The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Dactolisib.
Peginesatide The risk or severity of Thrombosis can be increased when Peginesatide is combined with Dactolisib.
Methoxy polyethylene glycol-epoetin beta The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Dactolisib.
Lidocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Quinisocaine.
Nelarabine The risk or severity of adverse effects can be increased when Nelarabine is combined with Dactolisib.
Ambroxol The risk or severity of methemoglobinemia can be increased when Dactolisib is combined with Ambroxol.
Etrasimod The risk or severity of immunosuppression can be increased when Dactolisib is combined with Etrasimod.

Target Protein

Serine/threonine-protein kinase mTOR MTOR
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG

Referensi & Sumber

Belum ada data referensi/link/attachment untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field referensi.

Contoh Produk & Brand

Produk: 0 • International brands: 0
Belum ada data produk/brand untuk obat ini pada database. Jalankan import DrugBank untuk mengisi field produk/brand.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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