Peringatan Keamanan

Oral LD50 for myrrh oil in rats is 1650mg/kg MSDS. The *Commiphora erlangeriana* species is poisonous to humans and other mammals A19598.

Myrrh

DB11605

small molecule approved

Deskripsi

Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, obtained from Commiphora abyssinica, Burseraceae.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

0 Data
Tidak ada data.

Target Protein

Bile acid receptor NR1H4
Nuclear receptor subfamily 1 group I member 2 NR1I2
Peroxisome proliferator-activated receptor alpha PPARA

Referensi & Sumber

Artikel (PubMed)
  • PMID: 22626923
    Shen T, Li GH, Wang XN, Lou HX: The genus Commiphora: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 2012 Jul 13;142(2):319-30. doi: 10.1016/j.jep.2012.05.025. Epub 2012 May 21.
  • PMID: 21827494
    Cheng YW, Cheah KP, Lin CW, Li JS, Yu WY, Chang ML, Yeh GC, Chen SH, Choy CS, Hu CM: Myrrh mediates haem oxygenase-1 expression to suppress the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages. J Pharm Pharmacol. 2011 Sep;63(9):1211-8. doi: 10.1111/j.2042-7158.2011.01329.x. Epub 2011 Jul 15.
  • PMID: 16399617
    Manjula N, Gayathri B, Vinaykumar KS, Shankernarayanan NP, Vishwakarma RA, Balakrishnan A: Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-alpha, IL-1beta and IL-2. Int Immunopharmacol. 2006 Feb;6(2):122-32. Epub 2005 Jul 20.
  • PMID: 18640253
    Paraskeva MP, van Vuuren SF, van Zyl RL, Davids H, Viljoen AM: The in vitro biological activity of selected South African Commiphora species. J Ethnopharmacol. 2008 Oct 28;119(3):673-9. doi: 10.1016/j.jep.2008.06.029. Epub 2008 Jul 2.
  • PMID: 21167270
    Su S, Wang T, Duan JA, Zhou W, Hua YQ, Tang YP, Yu L, Qian DW: Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha. J Ethnopharmacol. 2011 Mar 24;134(2):251-8. doi: 10.1016/j.jep.2010.12.003. Epub 2010 Dec 15.
  • PMID: 16275996
    Singh SV, Zeng Y, Xiao D, Vogel VG, Nelson JB, Dhir R, Tripathi YB: Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak. Mol Cancer Ther. 2005 Nov;4(11):1747-54.
  • PMID: 17671214
    Singh SV, Choi S, Zeng Y, Hahm ER, Xiao D: Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase. Cancer Res. 2007 Aug 1;67(15):7439-49.
  • PMID: 19446652
    Abdul-Ghani RA, Loutfy N, Hassan A: Myrrh and trematodoses in Egypt: an overview of safety, efficacy and effectiveness profiles. Parasitol Int. 2009 Sep;58(3):210-4. doi: 10.1016/j.parint.2009.04.006. Epub 2009 May 13.
Menampilkan 8 dari 17 artikel.

Contoh Produk & Brand

Produk: 7 • International brands: 0
Produk
  • Chase Coldsorex
    Liquid • - • Topical • Canada • OTC • Approved
  • CHI. JOA (Anti-inflammatory effect, antibacterial effect, stomatitis improvement, plaque removal)
    Powder • - • Topical • US • OTC
  • Cold Sore Lotion
    Lotion • - • Topical • Canada • OTC • Approved
  • LA FEMME V Feminine Cleanser
    Tablet • - • Vaginal • US • OTC
  • Lotion Pour Feux Sauvages
    Liquid • - • Topical • Canada • OTC • Approved
  • Plaster MandAHerbalPlaster
    Patch • - • Topical • US • OTC
  • Teinture De Myrrhe
    Liquid • 20 g / 100 mL • Dental; Topical • Canada • OTC • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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