Peringatan Keamanan

Some adverse effects at the injection site include pain, discomfort, pyrexia, and erythema, rash, hemorrhage, hematoma and rarely ulcer and necrosis. Other unwanted effects include severe hypersensitivity reactions, dyspnea, generalized rash and syncope.

Tuberculin purified protein derivative

DB11601

biotech approved

Deskripsi

Tuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with *Mycobacterium tuberculosis* through early diagnosis and appropriate therapeutic intervention. The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium tuberculosis. It is included in the World Health Organization's List of Essential Medicines.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

0 Data
Tidak ada data.

Target Protein

Toll-like receptor 2 TLR2

Referensi & Sumber

Artikel (PubMed)
  • PMID: 22762692
    Yang H, Kruh-Garcia NA, Dobos KM: Purified protein derivatives of tuberculin--past, present, and future. FEMS Immunol Med Microbiol. 2012 Dec;66(3):273-80. doi: 10.1111/j.1574-695X.2012.01002.x. Epub 2012 Aug 1.
  • PMID: 23870090
    Prasad TS, Verma R, Kumar S, Nirujogi RS, Sathe GJ, Madugundu AK, Sharma J, Puttamallesh VN, Ganjiwale A, Myneedu VP, Chatterjee A, Pandey A, Harsha H, Narayana J: Proteomic analysis of purified protein derivative of Mycobacterium tuberculosis. Clin Proteomics. 2013 Jul 19;10(1):8. doi: 10.1186/1559-0275-10-8.
  • PMID: 11972637
    Matsuyama W, Kubota R, Hashiguchi T, Momi H, Kawabata M, Nakagawa M, Arimura K, Osame M: Purified protein derivative of tuberculin upregulates the expression of vascular endothelial growth factor in T lymphocytes in vitro. Immunology. 2002 May;106(1):96-101.
Textbook
  • ISBN: 978-0-7020-3471-8
    6. (2012). In Rang and Dale's Pharmacology (7th ed., pp. 82-84). Edinburgh: Elsevier/Churchill Livingstone.

Contoh Produk & Brand

Produk: 12 • International brands: 0
Produk
  • Aplisol
    Injection • 5 [iU]/0.1mL • Intradermal • US • Approved
  • Aplisol
    Injection • 5 [iU]/0.1mL • Intradermal • US • Approved
  • Aplisol
    Injection • 5 [iU]/0.1mL • Intradermal • US • Approved
  • Aplisol
    Injection • 5 [iU]/0.1mL • Intradermal • US • Approved
  • Tuberculin Ppd (mantoux)
    Liquid • 1 tub / 0.1 mL • Intradermal • Canada • Approved
  • Tuberculin Ppd (mantoux)
    Liquid • 250 tub / 0.1 mL • Intradermal • Canada • Approved
  • Tubersol
    Injection, solution • 5 [iU]/0.1mL • Intradermal • US • Approved
  • Tubersol
    Injection, solution • 5 [iU]/0.1mL • Intradermal • US • Approved
Menampilkan 8 dari 12 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
© 2025 Digital Pharmacy Research - Universitas Esa Unggul