Tricaine

DB11552

small molecule vet_approved

Deskripsi

Tricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish. It is also the only anesthetic licensed in the United States for use in fin fish that are intended for human consumption.

Struktur Molekul 2D

Berat 165.1891
Wujud -

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

662 Data
Buprenorphine Tricaine may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Droperidol Droperidol may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Hydrocodone Tricaine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
Hydroxyzine Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Magnesium sulfate The therapeutic efficacy of Tricaine can be increased when used in combination with Magnesium sulfate.
Methotrimeprazine Tricaine may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
Metyrosine Tricaine may increase the sedative activities of Metyrosine.
Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Mirtazapine Tricaine may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Orphenadrine Tricaine may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Paraldehyde Tricaine may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Pramipexole Tricaine may increase the sedative activities of Pramipexole.
Ropinirole Tricaine may increase the sedative activities of Ropinirole.
Rotigotine Tricaine may increase the sedative activities of Rotigotine.
Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Tricaine.
Sodium oxybate Tricaine may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
Suvorexant Tricaine may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Thalidomide Tricaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Zolpidem Tricaine may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Tricaine.
Ethanol Tricaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Azelastine Tricaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Brimonidine Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Fluvoxamine The risk or severity of adverse effects can be increased when Tricaine is combined with Fluvoxamine.
Citalopram The risk or severity of adverse effects can be increased when Tricaine is combined with Citalopram.
Duloxetine The risk or severity of adverse effects can be increased when Tricaine is combined with Duloxetine.
Trazodone The risk or severity of adverse effects can be increased when Tricaine is combined with Trazodone.
Paroxetine The risk or severity of adverse effects can be increased when Tricaine is combined with Paroxetine.
Sertraline The risk or severity of adverse effects can be increased when Tricaine is combined with Sertraline.
Sibutramine The risk or severity of adverse effects can be increased when Tricaine is combined with Sibutramine.
Nefazodone The risk or severity of adverse effects can be increased when Tricaine is combined with Nefazodone.
Escitalopram The risk or severity of adverse effects can be increased when Tricaine is combined with Escitalopram.
Zimelidine The risk or severity of adverse effects can be increased when Tricaine is combined with Zimelidine.
Dapoxetine The risk or severity of adverse effects can be increased when Tricaine is combined with Dapoxetine.
Milnacipran The risk or severity of adverse effects can be increased when Tricaine is combined with Milnacipran.
Desvenlafaxine The risk or severity of adverse effects can be increased when Tricaine is combined with Desvenlafaxine.
Seproxetine The risk or severity of adverse effects can be increased when Tricaine is combined with Seproxetine.
Indalpine The risk or severity of adverse effects can be increased when Tricaine is combined with Indalpine.
Ritanserin The risk or severity of adverse effects can be increased when Tricaine is combined with Ritanserin.
Alaproclate The risk or severity of adverse effects can be increased when Tricaine is combined with Alaproclate.
Amitriptyline The risk or severity of CNS depression can be increased when Amitriptyline is combined with Tricaine.
Cyproheptadine The risk or severity of CNS depression can be increased when Cyproheptadine is combined with Tricaine.
Imipramine The risk or severity of CNS depression can be increased when Imipramine is combined with Tricaine.
Nortriptyline The risk or severity of CNS depression can be increased when Nortriptyline is combined with Tricaine.
Amoxapine The risk or severity of CNS depression can be increased when Amoxapine is combined with Tricaine.
Propiomazine The risk or severity of CNS depression can be increased when Propiomazine is combined with Tricaine.
Maprotiline The risk or severity of CNS depression can be increased when Maprotiline is combined with Tricaine.
Doxepin The risk or severity of CNS depression can be increased when Doxepin is combined with Tricaine.
Desipramine The risk or severity of CNS depression can be increased when Desipramine is combined with Tricaine.
Pizotifen The risk or severity of CNS depression can be increased when Pizotifen is combined with Tricaine.
Dosulepin The risk or severity of CNS depression can be increased when Dosulepin is combined with Tricaine.
Zopiclone The risk or severity of adverse effects can be increased when Tricaine is combined with Zopiclone.
Botulinum toxin type B The risk or severity of CNS depression can be increased when Botulinum toxin type B is combined with Tricaine.
Botulinum toxin type A The risk or severity of CNS depression can be increased when Botulinum toxin type A is combined with Tricaine.
Tryptophan The risk or severity of CNS depression can be increased when Tryptophan is combined with Tricaine.
Baclofen Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tricaine.
Lorazepam The risk or severity of CNS depression can be increased when Lorazepam is combined with Tricaine.
Ethchlorvynol The risk or severity of CNS depression can be increased when Ethchlorvynol is combined with Tricaine.
Succinylcholine The risk or severity of CNS depression can be increased when Succinylcholine is combined with Tricaine.
Reserpine The risk or severity of CNS depression can be increased when Reserpine is combined with Tricaine.
Eletriptan The risk or severity of CNS depression can be increased when Eletriptan is combined with Tricaine.
Enflurane The risk or severity of CNS depression can be increased when Enflurane is combined with Tricaine.
Temazepam The risk or severity of CNS depression can be increased when Temazepam is combined with Tricaine.
Reboxetine The risk or severity of CNS depression can be increased when Reboxetine is combined with Tricaine.
Butabarbital The risk or severity of CNS depression can be increased when Butabarbital is combined with Tricaine.
Butalbital The risk or severity of CNS depression can be increased when Butalbital is combined with Tricaine.
Methysergide The risk or severity of CNS depression can be increased when Methysergide is combined with Tricaine.
Cabergoline The risk or severity of CNS depression can be increased when Cabergoline is combined with Tricaine.
Phenytoin The risk or severity of CNS depression can be increased when Phenytoin is combined with Tricaine.
Topiramate The risk or severity of CNS depression can be increased when Topiramate is combined with Tricaine.
Clemastine The risk or severity of CNS depression can be increased when Clemastine is combined with Tricaine.
Venlafaxine The risk or severity of CNS depression can be increased when Venlafaxine is combined with Tricaine.
Etomidate The risk or severity of CNS depression can be increased when Etomidate is combined with Tricaine.
Morphine The risk or severity of CNS depression can be increased when Morphine is combined with Tricaine.
Talbutal The risk or severity of CNS depression can be increased when Talbutal is combined with Tricaine.
Pentobarbital The risk or severity of CNS depression can be increased when Pentobarbital is combined with Tricaine.
Valproic acid The risk or severity of CNS depression can be increased when Valproic acid is combined with Tricaine.
Zolmitriptan The risk or severity of CNS depression can be increased when Zolmitriptan is combined with Tricaine.
Codeine The risk or severity of CNS depression can be increased when Codeine is combined with Tricaine.
Dihydroergotamine The risk or severity of CNS depression can be increased when Dihydroergotamine is combined with Tricaine.
Tolcapone The risk or severity of CNS depression can be increased when Tolcapone is combined with Tricaine.
Hydromorphone The risk or severity of CNS depression can be increased when Hydromorphone is combined with Tricaine.
Olanzapine The risk or severity of CNS depression can be increased when Olanzapine is combined with Tricaine.
Cetirizine The risk or severity of CNS depression can be increased when Cetirizine is combined with Tricaine.
Protriptyline The risk or severity of CNS depression can be increased when Protriptyline is combined with Tricaine.
Trimethadione The risk or severity of CNS depression can be increased when Trimethadione is combined with Tricaine.
Clobazam The risk or severity of sedation, somnolence, and CNS depression can be increased when Clobazam is combined with Tricaine.
Chlorzoxazone The risk or severity of CNS depression can be increased when Chlorzoxazone is combined with Tricaine.
Clozapine The risk or severity of CNS depression can be increased when Clozapine is combined with Tricaine.
Meprobamate The risk or severity of CNS depression can be increased when Meprobamate is combined with Tricaine.
Thiethylperazine The risk or severity of CNS depression can be increased when Thiethylperazine is combined with Tricaine.
Palonosetron The risk or severity of CNS depression can be increased when Palonosetron is combined with Tricaine.
Sulpiride The risk or severity of CNS depression can be increased when Sulpiride is combined with Tricaine.
Alprazolam The risk or severity of CNS depression can be increased when Alprazolam is combined with Tricaine.
Dexbrompheniramine The risk or severity of CNS depression can be increased when Dexbrompheniramine is combined with Tricaine.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 6202
    Ohr EA: Tricaine methanesulfonate--II. Effects on transport of NaCl and H2O. Comp Biochem Physiol C. 1976;54(1):19-22.
  • PMID: 19245747
    Conroy CJ, Papenfuss T, Parker J, Hahn NE: Use of tricaine methanesulfonate (MS222) for euthanasia of reptiles. J Am Assoc Lab Anim Sci. 2009 Jan;48(1):28-32.
  • PMID: 6201
    Ohr EA: Tricaine methanesulfonate--1. pH and its effects on anesthetic potency. Comp Biochem Physiol C. 1976;54(1):13-7.
  • PMID: 15442296
    FRIDDLE SB, SNIESZKO SF: Effect of tricaine methanesulfonate on the determination of sulfonamides. Science. 1950 Aug 11;112(2902):181-2.
  • PMID: 203816
    La Touche YD, Kimeldorf DJ: An effect of tricaine methanesulfonate on the electroretinogram of Taricha granulosa. Life Sci. 1978 Feb;22(7):597-602.
  • PMID: 23805553
    Posner LP, Scott GN, Law JM: Repeated exposure of goldfish (Carassius auratus) to tricaine methanesulfonate (MS-222). J Zoo Wildl Med. 2013 Jun;44(2):340-7.
  • PMID: 19930828
    Wilson JM, Bunte RM, Carty AJ: Evaluation of rapid cooling and tricaine methanesulfonate (MS222) as methods of euthanasia in zebrafish (Danio rerio). J Am Assoc Lab Anim Sci. 2009 Nov;48(6):785-9.
  • PMID: 3712895
    Hikasa Y, Takase K, Ogasawara T, Ogasawara S: Anesthesia and recovery with tricaine methanesulfonate, eugenol and thiopental sodium in the carp, Cyprinus carpio. Nihon Juigaku Zasshi. 1986 Apr;48(2):341-51.
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