Romifidine

DB11543

small molecule vet_approved

Deskripsi

Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.

Struktur Molekul 2D

Berat 258.094
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

1144 Data
Valsartan Romifidine may decrease the antihypertensive activities of Valsartan.
Ramipril Romifidine may decrease the antihypertensive activities of Ramipril.
Remikiren Romifidine may decrease the antihypertensive activities of Remikiren.
Torasemide Romifidine may decrease the antihypertensive activities of Torasemide.
Isradipine Romifidine may decrease the antihypertensive activities of Isradipine.
Olmesartan Romifidine may decrease the antihypertensive activities of Olmesartan.
Chlorthalidone Romifidine may decrease the antihypertensive activities of Chlorthalidone.
Nitroprusside Romifidine may decrease the antihypertensive activities of Nitroprusside.
Diltiazem Romifidine may decrease the antihypertensive activities of Diltiazem.
Minoxidil Romifidine may decrease the antihypertensive activities of Minoxidil.
Treprostinil Romifidine may decrease the antihypertensive activities of Treprostinil.
Amlodipine Romifidine may decrease the antihypertensive activities of Amlodipine.
Nimodipine Romifidine may decrease the antihypertensive activities of Nimodipine.
Nisoldipine Romifidine may decrease the antihypertensive activities of Nisoldipine.
Bendroflumethiazide Romifidine may decrease the antihypertensive activities of Bendroflumethiazide.
Fosinopril Romifidine may decrease the antihypertensive activities of Fosinopril.
Trandolapril Romifidine may decrease the antihypertensive activities of Trandolapril.
Metolazone Romifidine may decrease the antihypertensive activities of Metolazone.
Lercanidipine Romifidine may decrease the antihypertensive activities of Lercanidipine.
Benazepril Romifidine may decrease the antihypertensive activities of Benazepril.
Bosentan Romifidine may decrease the antihypertensive activities of Bosentan.
Enalapril Romifidine may decrease the antihypertensive activities of Enalapril.
Cyclothiazide Romifidine may decrease the antihypertensive activities of Cyclothiazide.
Candoxatril Romifidine may decrease the antihypertensive activities of Candoxatril.
Mecamylamine Romifidine may decrease the antihypertensive activities of Mecamylamine.
Losartan Romifidine may decrease the antihypertensive activities of Losartan.
Moexipril Romifidine may decrease the antihypertensive activities of Moexipril.
Eplerenone Romifidine may decrease the antihypertensive activities of Eplerenone.
Lisinopril Romifidine may decrease the antihypertensive activities of Lisinopril.
Nitroglycerin Romifidine may decrease the antihypertensive activities of Nitroglycerin.
Hydroflumethiazide Romifidine may decrease the antihypertensive activities of Hydroflumethiazide.
Cryptenamine Romifidine may decrease the antihypertensive activities of Cryptenamine.
Perindopril Romifidine may decrease the antihypertensive activities of Perindopril.
Candesartan cilexetil Romifidine may decrease the antihypertensive activities of Candesartan cilexetil.
Fenoldopam Romifidine may decrease the antihypertensive activities of Fenoldopam.
Indapamide Romifidine may decrease the antihypertensive activities of Indapamide.
Tadalafil Romifidine may decrease the antihypertensive activities of Tadalafil.
Eprosartan Romifidine may decrease the antihypertensive activities of Eprosartan.
Chlorothiazide Romifidine may decrease the antihypertensive activities of Chlorothiazide.
Quinapril Romifidine may decrease the antihypertensive activities of Quinapril.
Telmisartan Romifidine may decrease the antihypertensive activities of Telmisartan.
Methyldopa Romifidine may decrease the antihypertensive activities of Methyldopa.
Hydrochlorothiazide Romifidine may decrease the antihypertensive activities of Hydrochlorothiazide.
Trichlormethiazide Romifidine may decrease the antihypertensive activities of Trichlormethiazide.
Irbesartan Romifidine may decrease the antihypertensive activities of Irbesartan.
Nitrendipine Romifidine may decrease the antihypertensive activities of Nitrendipine.
Deserpidine Romifidine may decrease the antihypertensive activities of Deserpidine.
Pentolinium Romifidine may decrease the antihypertensive activities of Pentolinium.
Trimethaphan Romifidine may decrease the antihypertensive activities of Trimethaphan.
Diazoxide Romifidine may decrease the antihypertensive activities of Diazoxide.
Captopril Romifidine may decrease the antihypertensive activities of Captopril.
Epoprostenol Romifidine may decrease the antihypertensive activities of Epoprostenol.
Bepridil Romifidine may decrease the antihypertensive activities of Bepridil.
Hydralazine Romifidine may decrease the antihypertensive activities of Hydralazine.
Polythiazide Romifidine may decrease the antihypertensive activities of Polythiazide.
Cilazapril Romifidine may decrease the antihypertensive activities of Cilazapril.
Saprisartan Romifidine may decrease the antihypertensive activities of Saprisartan.
Spirapril Romifidine may decrease the antihypertensive activities of Spirapril.
Mibefradil Romifidine may decrease the antihypertensive activities of Mibefradil.
Tienilic acid Romifidine may decrease the antihypertensive activities of Tienilic acid.
Debrisoquine Romifidine may decrease the antihypertensive activities of Debrisoquine.
Sitaxentan Romifidine may decrease the antihypertensive activities of Sitaxentan.
Ambrisentan Romifidine may decrease the antihypertensive activities of Ambrisentan.
Diethylnorspermine Romifidine may decrease the antihypertensive activities of Diethylnorspermine.
Nilvadipine Romifidine may decrease the antihypertensive activities of Nilvadipine.
Pinacidil Romifidine may decrease the antihypertensive activities of Pinacidil.
Temocapril Romifidine may decrease the antihypertensive activities of Temocapril.
Riociguat Romifidine may decrease the antihypertensive activities of Riociguat.
Macitentan Romifidine may decrease the antihypertensive activities of Macitentan.
Aliskiren Romifidine may decrease the antihypertensive activities of Aliskiren.
Nicorandil Romifidine may decrease the antihypertensive activities of Nicorandil.
Efonidipine Romifidine may decrease the antihypertensive activities of Efonidipine.
Lacidipine Romifidine may decrease the antihypertensive activities of Lacidipine.
Manidipine Romifidine may decrease the antihypertensive activities of Manidipine.
Rauwolfia serpentina root Romifidine may decrease the antihypertensive activities of Rauwolfia serpentina root.
Enalaprilat Romifidine may decrease the antihypertensive activities of Enalaprilat.
Selexipag Romifidine may decrease the antihypertensive activities of Selexipag.
Angiotensin 1-7 Romifidine may decrease the antihypertensive activities of Angiotensin 1-7.
Imidapril Romifidine may decrease the antihypertensive activities of Imidapril.
BQ-123 Romifidine may decrease the antihypertensive activities of BQ-123.
Cicletanine Romifidine may decrease the antihypertensive activities of Cicletanine.
Dihydralazine Romifidine may decrease the antihypertensive activities of Dihydralazine.
Zofenopril Romifidine may decrease the antihypertensive activities of Zofenopril.
Guanoxan Romifidine may decrease the antihypertensive activities of Guanoxan.
Delapril Romifidine may decrease the antihypertensive activities of Delapril.
Vincamine Romifidine may decrease the antihypertensive activities of Vincamine.
Linsidomine Romifidine may decrease the antihypertensive activities of Linsidomine.
Guanoxabenz Romifidine may decrease the antihypertensive activities of Guanoxabenz.
Tolonidine Romifidine may decrease the antihypertensive activities of Tolonidine.
Endralazine Romifidine may decrease the antihypertensive activities of Endralazine.
Cadralazine Romifidine may decrease the antihypertensive activities of Cadralazine.
Cyclopenthiazide Romifidine may decrease the antihypertensive activities of Cyclopenthiazide.
Bietaserpine Romifidine may decrease the antihypertensive activities of Bietaserpine.
Guanazodine Romifidine may decrease the antihypertensive activities of Guanazodine.
Methoserpidine Romifidine may decrease the antihypertensive activities of Methoserpidine.
Guanoclor Romifidine may decrease the antihypertensive activities of Guanoclor.
Muzolimine Romifidine may decrease the antihypertensive activities of Muzolimine.
Xipamide Romifidine may decrease the antihypertensive activities of Xipamide.
Candesartan Romifidine may decrease the antihypertensive activities of Candesartan.
Dexniguldipine Romifidine may decrease the antihypertensive activities of Dexniguldipine.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 9444638
    England GC, Watts N: Effect of romifidine and romifidine-butorphanol for sedation in dogs. J Small Anim Pract. 1997 Dec;38(12):561-4.
  • PMID: 8642795
    England GC, Flack TE, Hollingworth E, Hammond R: Sedative effects of romifidine in the dog. J Small Anim Pract. 1996 Jan;37(1):19-25.
  • PMID: 8178417
    Browning AP, Collins JA: Sedation of horses with romifidine and butorphanol. Vet Rec. 1994 Jan 22;134(4):90-1.
  • PMID: 11327453
    Pypendop BH, Verstegen JP: Cardiovascular effects of romifidine in dogs. Am J Vet Res. 2001 Apr;62(4):490-5.
  • PMID: 12184699
    Selmi AL, Barbudo-Selmi GR, Moreira CF, Martins CS, Lins BT, Mendes GM, McManus C: Evaluation of sedative and cardiorespiratory effects of romifidine and romifidine-butorphanol in cats. J Am Vet Med Assoc. 2002 Aug 15;221(4):506-10.
  • PMID: 11513266
    Aithal HP, Amarpal, Kinjavdekar P, Pawde AM, Pratap K: Analgesic and cardiopulmonary effects of intrathecally administered romifidine or romifidine and ketamine in goats (Capra hircus). J S Afr Vet Assoc. 2001 Jun;72(2):84-91.
  • PMID: 12027592
    Freeman SL, Bowen IM, Bettschart-Wolfensberger R, Alibhai HI, England GC: Cardiovascular effects of romifidine in the standing horse. Res Vet Sci. 2002 Apr;72(2):123-9.
  • PMID: 19538572
    Marzok M, El-Khodery S: Sedative and analgesic effects of romifidine in camels (Camelus dromedarius). Vet Anaesth Analg. 2009 Jul;36(4):352-60. doi: 10.1111/j.1467-2995.2009.00473.x.
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