Sarafloxacin

DB11491

small molecule vet_approved withdrawn

Deskripsi

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.

Struktur Molekul 2D

Berat 385.3641
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

935 Data
Didanosine Didanosine can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Sarafloxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Sarafloxacin.
Nitrofurantoin The therapeutic efficacy of Sarafloxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Sarafloxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Sarafloxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Sarafloxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Sarafloxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Sarafloxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Sarafloxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Sarafloxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Sarafloxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Sarafloxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Sarafloxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Sarafloxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Sarafloxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Sarafloxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Sarafloxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Sarafloxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Sarafloxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Sarafloxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Sarafloxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Sarafloxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Sarafloxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Sarafloxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Sarafloxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Sarafloxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Sarafloxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Sarafloxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Sarafloxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Sarafloxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Sarafloxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Sarafloxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Sarafloxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Sarafloxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Sarafloxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Sarafloxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Sarafloxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Sarafloxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Sarafloxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Sarafloxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Sarafloxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Sarafloxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Sarafloxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Sarafloxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Sarafloxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Sarafloxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Sarafloxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Sarafloxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Sarafloxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Sarafloxacin.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Sarafloxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Sarafloxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Sarafloxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Sarafloxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Sarafloxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Sarafloxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Sarafloxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Sarafloxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Sarafloxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Sarafloxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Sarafloxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Sarafloxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Sarafloxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Sarafloxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Sarafloxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Sarafloxacin.
Insulin beef The therapeutic efficacy of Insulin beef can be increased when used in combination with Sarafloxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Sarafloxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Sarafloxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Sarafloxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Sarafloxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Sarafloxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Sarafloxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Sarafloxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Sarafloxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Sarafloxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Sarafloxacin.
Omarigliptin The therapeutic efficacy of Omarigliptin can be increased when used in combination with Sarafloxacin.
Carmegliptin The therapeutic efficacy of Carmegliptin can be increased when used in combination with Sarafloxacin.
Gemigliptin The therapeutic efficacy of Gemigliptin can be increased when used in combination with Sarafloxacin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 10416362
    Authors unspecified: Evaluation of certain veterinary drug residues in food. Fiftieth report of the joint FAO/WHO Expert Committee on Food Additives. World Health Organ Tech Rep Ser. 1999;888:i-vii, 1-95.
  • PMID: 9823579
    Gingerich WH, Stehly GR, Clark KJ, Hayton WL: Crop grouping: a proposal for public aquaculture. Vet Hum Toxicol. 1998;40 Suppl 2:24-31.

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