Tulathromycin A

DB11474

small molecule vet_approved

Deskripsi

Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease in cattle and swine respiratory disease in pigs. It is marketed by Pfizer Inc. under the tradename Draxxin.

Struktur Molekul 2D

Berat 806.092
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

55 Data
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Tulathromycin A.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Tulathromycin A.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Tulathromycin A.
Dicoumarol The risk or severity of bleeding can be increased when Tulathromycin A is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when Tulathromycin A is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when Tulathromycin A is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when Tulathromycin A is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when Tulathromycin A is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when Tulathromycin A is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when Tulathromycin A is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when Tulathromycin A is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when Tulathromycin A is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when Tulathromycin A is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when Tulathromycin A is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when Tulathromycin A is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when Tulathromycin A is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when Tulathromycin A is combined with (S)-Warfarin.
Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Tulathromycin A.
Vibrio cholerae CVD 103-HgR strain live antigen The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tulathromycin A.
Estetrol The therapeutic efficacy of Estetrol can be decreased when used in combination with Tulathromycin A.
Lidocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Quinisocaine.
Cisatracurium Tulathromycin A may increase the neuromuscular blocking activities of Cisatracurium.
Ambroxol The risk or severity of methemoglobinemia can be increased when Tulathromycin A is combined with Ambroxol.
Fecal microbiota The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with Tulathromycin A.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 17472660
    Washburn KE, Bissett W, Fajt V, Clubb F, Fosgate GT, Libal M, Smyre KE, Cass KL: The safety of tulathromycin administration in goats. J Vet Pharmacol Ther. 2007 Jun;30(3):267-70.
  • PMID: 15156657
    Morselt M: Tulathromycin, a new antibiotic for farm animals. Tijdschr Diergeneeskd. 2004 May 1;129(9):306-7.
  • PMID: 20860100
    Clothier KA, Jordan DM, Loynachan AT, Griffith RW: Safety evaluation of tulathromycin use in the caprine species: tulathromycin toxicity assessment in goats. J Vet Pharmacol Ther. 2010 Oct;33(5):499-502.
  • PMID: 20638089
    Young G, Smith GW, Leavens TL, Wetzlich SE, Baynes RE, Mason SE, Riviere JE, Tell LA: Pharmacokinetics of tulathromycin following subcutaneous administration in meat goats. Res Vet Sci. 2011 Jun;90(3):477-9. doi: 10.1016/j.rvsc.2010.06.025. Epub 2010 Jul 16.
  • PMID: 21727065
    Er A, Altan F, Cetin G, Dik B, Elmas M, Yazar E: Assessment of the cardiotoxicity of tulathromycin in rabbits. Acta Vet Hung. 2011 Sep;59(3):327-35. doi: 10.1556/AVet.2011.015.
  • PMID: 15305848
    Benchaoui HA, Nowakowski M, Sherington J, Rowan TG, Sunderland SJ: Pharmacokinetics and lung tissue concentrations of tulathromycin in swine. J Vet Pharmacol Ther. 2004 Aug;27(4):203-10.
  • PMID: 19177332
    Van Donkersgoed J, Berg J, Hendrick S: Comparison of florfenicol and tulathromycin for the treatment of undifferentiated fever in Alberta feedlot calves. Vet Ther. 2008 Winter;9(4):275-81.
  • PMID: 16094568
    Nutsch RG, Hart FJ, Rooney KA, Weigel DJ, Kilgore WR, Skogerboe TL: Efficacy of tulathromycin injectable solution for the treatment of naturally occurring Swine respiratory disease. Vet Ther. 2005 Summer;6(2):214-24.
Menampilkan 8 dari 10 artikel.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Draxxin

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