Tilmicosin

DB11471

small molecule investigational vet_approved

Deskripsi

Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.

Struktur Molekul 2D

Berat 869.147
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

173 Data
Alfentanil The serum concentration of Alfentanil can be increased when it is combined with Tilmicosin.
Alprazolam The serum concentration of Alprazolam can be increased when it is combined with Tilmicosin.
Buspirone The metabolism of Buspirone can be decreased when combined with Tilmicosin.
Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Tilmicosin.
Cisapride The serum concentration of Cisapride can be increased when it is combined with Tilmicosin.
Disopyramide Tilmicosin may increase the QTc-prolonging activities of Disopyramide.
Estazolam The serum concentration of Estazolam can be increased when it is combined with Tilmicosin.
Midazolam The serum concentration of Midazolam can be increased when it is combined with Tilmicosin.
Quinine The serum concentration of Quinine can be increased when it is combined with Tilmicosin.
Quinidine The serum concentration of Quinidine can be increased when it is combined with Tilmicosin.
Repaglinide The serum concentration of Repaglinide can be increased when it is combined with Tilmicosin.
Sirolimus The metabolism of Sirolimus can be decreased when combined with Tilmicosin.
Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Tilmicosin.
Terfenadine The serum concentration of Terfenadine can be increased when it is combined with Tilmicosin.
Triazolam The serum concentration of Triazolam can be increased when it is combined with Tilmicosin.
Telaprevir The serum concentration of Telaprevir can be increased when it is combined with Tilmicosin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Tilmicosin.
Vintafolide The serum concentration of Vintafolide can be increased when it is combined with Tilmicosin.
Vincamine The serum concentration of Vincamine can be increased when it is combined with Tilmicosin.
Vindesine The serum concentration of Vindesine can be increased when it is combined with Tilmicosin.
Vinorelbine The serum concentration of Vinorelbine can be increased when it is combined with Tilmicosin.
Vincristine The serum concentration of Vincristine can be increased when it is combined with Tilmicosin.
Vinblastine The serum concentration of Vinblastine can be increased when it is combined with Tilmicosin.
Vinflunine The serum concentration of Vinflunine can be increased when it is combined with Tilmicosin.
Acetyldigitoxin The serum concentration of Acetyldigitoxin can be increased when it is combined with Tilmicosin.
Deslanoside The serum concentration of Deslanoside can be increased when it is combined with Tilmicosin.
Ouabain The serum concentration of Ouabain can be increased when it is combined with Tilmicosin.
Oleandrin The serum concentration of Oleandrin can be increased when it is combined with Tilmicosin.
Cymarin The serum concentration of Cymarin can be increased when it is combined with Tilmicosin.
Proscillaridin The serum concentration of Proscillaridin can be increased when it is combined with Tilmicosin.
Metildigoxin The serum concentration of Metildigoxin can be increased when it is combined with Tilmicosin.
Lanatoside C The serum concentration of Lanatoside C can be increased when it is combined with Tilmicosin.
Gitoformate The serum concentration of Gitoformate can be increased when it is combined with Tilmicosin.
Acetyldigoxin The serum concentration of Acetyldigoxin can be increased when it is combined with Tilmicosin.
Peruvoside The serum concentration of Peruvoside can be increased when it is combined with Tilmicosin.
Digitoxin The serum concentration of Digitoxin can be increased when it is combined with Tilmicosin.
Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Tilmicosin.
Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Tilmicosin.
Dicoumarol The serum concentration of Dicoumarol can be increased when it is combined with Tilmicosin.
Phenindione The serum concentration of Phenindione can be increased when it is combined with Tilmicosin.
Coumarin The serum concentration of Coumarin can be increased when it is combined with Tilmicosin.
Tioclomarol The serum concentration of Tioclomarol can be increased when it is combined with Tilmicosin.
Ethyl biscoumacetate The serum concentration of Ethyl biscoumacetate can be increased when it is combined with Tilmicosin.
Diphenadione The serum concentration of Diphenadione can be increased when it is combined with Tilmicosin.
4-hydroxycoumarin The serum concentration of 4-hydroxycoumarin can be increased when it is combined with Tilmicosin.
Fluindione The serum concentration of Fluindione can be increased when it is combined with Tilmicosin.
Clorindione The serum concentration of Clorindione can be increased when it is combined with Tilmicosin.
Warfarin The serum concentration of Warfarin can be increased when it is combined with Tilmicosin.
Phenprocoumon The serum concentration of Phenprocoumon can be increased when it is combined with Tilmicosin.
Acenocoumarol The serum concentration of Acenocoumarol can be increased when it is combined with Tilmicosin.
(R)-warfarin The serum concentration of (R)-warfarin can be increased when it is combined with Tilmicosin.
(S)-Warfarin The serum concentration of (S)-Warfarin can be increased when it is combined with Tilmicosin.
Oxtriphylline The metabolism of Oxtriphylline can be decreased when combined with Tilmicosin.
Doxofylline The metabolism of Doxofylline can be decreased when combined with Tilmicosin.
Bamifylline The metabolism of Bamifylline can be decreased when combined with Tilmicosin.
Acefylline The metabolism of Acefylline can be decreased when combined with Tilmicosin.
Bufylline The metabolism of Bufylline can be decreased when combined with Tilmicosin.
Fenethylline The metabolism of Fenethylline can be decreased when combined with Tilmicosin.
Proxyphylline The metabolism of Proxyphylline can be decreased when combined with Tilmicosin.
Bromotheophylline The metabolism of Bromotheophylline can be decreased when combined with Tilmicosin.
Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Tilmicosin.
8-azaguanine The metabolism of 8-azaguanine can be decreased when combined with Tilmicosin.
7,9-Dimethylguanine The metabolism of 7,9-Dimethylguanine can be decreased when combined with Tilmicosin.
Xanthine The metabolism of Xanthine can be decreased when combined with Tilmicosin.
7-Deazaguanine The metabolism of 7-Deazaguanine can be decreased when combined with Tilmicosin.
Guanine The metabolism of Guanine can be decreased when combined with Tilmicosin.
9-Methylguanine The metabolism of 9-Methylguanine can be decreased when combined with Tilmicosin.
Peldesine The metabolism of Peldesine can be decreased when combined with Tilmicosin.
Hypoxanthine The metabolism of Hypoxanthine can be decreased when combined with Tilmicosin.
9-Deazaguanine The metabolism of 9-Deazaguanine can be decreased when combined with Tilmicosin.
Valomaciclovir The metabolism of Valomaciclovir can be decreased when combined with Tilmicosin.
3-isobutyl-1-methyl-7H-xanthine The metabolism of 3-isobutyl-1-methyl-7H-xanthine can be decreased when combined with Tilmicosin.
Uric acid The metabolism of Uric acid can be decreased when combined with Tilmicosin.
6-O-benzylguanine The metabolism of 6-O-benzylguanine can be decreased when combined with Tilmicosin.
Lisofylline The metabolism of Lisofylline can be decreased when combined with Tilmicosin.
Lobucavir The metabolism of Lobucavir can be decreased when combined with Tilmicosin.
Cafedrine The metabolism of Cafedrine can be decreased when combined with Tilmicosin.
Theodrenaline The metabolism of Theodrenaline can be decreased when combined with Tilmicosin.
Etamiphylline The metabolism of Etamiphylline can be decreased when combined with Tilmicosin.
Pentifylline The metabolism of Pentifylline can be decreased when combined with Tilmicosin.
Furafylline The metabolism of Furafylline can be decreased when combined with Tilmicosin.
Theobromine The metabolism of Theobromine can be decreased when combined with Tilmicosin.
Propentofylline The metabolism of Propentofylline can be decreased when combined with Tilmicosin.
Caffeine The metabolism of Caffeine can be decreased when combined with Tilmicosin.
8-chlorotheophylline The metabolism of 8-chlorotheophylline can be decreased when combined with Tilmicosin.
Mercaptopurine The metabolism of Mercaptopurine can be decreased when combined with Tilmicosin.
PCS-499 The metabolism of PCS-499 can be decreased when combined with Tilmicosin.
Theophylline The metabolism of Theophylline can be decreased when combined with Tilmicosin.
Aminophylline The metabolism of Aminophylline can be decreased when combined with Tilmicosin.
Methylergometrine The serum concentration of Methylergometrine can be increased when it is combined with Tilmicosin.
Lisuride The serum concentration of Lisuride can be increased when it is combined with Tilmicosin.
Nicergoline The serum concentration of Nicergoline can be increased when it is combined with Tilmicosin.
Ergoloid mesylate The serum concentration of Ergoloid mesylate can be increased when it is combined with Tilmicosin.
Pergolide The serum concentration of Pergolide can be increased when it is combined with Tilmicosin.
Ergometrine The serum concentration of Ergometrine can be increased when it is combined with Tilmicosin.
Lysergic acid diethylamide The serum concentration of Lysergic acid diethylamide can be increased when it is combined with Tilmicosin.
Dihydroergocornine The serum concentration of Dihydroergocornine can be increased when it is combined with Tilmicosin.
Dihydroergocristine The serum concentration of Dihydroergocristine can be increased when it is combined with Tilmicosin.
Dihydroergocryptine The serum concentration of Dihydroergocryptine can be increased when it is combined with Tilmicosin.
Terguride The serum concentration of Terguride can be increased when it is combined with Tilmicosin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 1858280
    Mee JF, O'Farrell K: Tilmicosin and calf pneumonia. Vet Rec. 1991 May 11;128(19):460.
  • PMID: 7975134
    McGuigan MA: Human exposures to tilmicosin (MICOTIL). Vet Hum Toxicol. 1994 Aug;36(4):306-8.
  • PMID: 8587151
    Ziv G, Shem-Tov M, Glickman A, Winkler M, Saran A: Tilmicosin antibacterial activity and pharmacokinetics in cows. J Vet Pharmacol Ther. 1995 Oct;18(5):340-5.
  • PMID: 15113165
    Zhang Y, Jiang H, Jin X, Shen Z, Shen J, Fu C, Guo J: Residue depletion of tilmicosin in chicken tissues. J Agric Food Chem. 2004 May 5;52(9):2602-5.
  • PMID: 16924727
    Authors unspecified: Industry guidance on the administration of tilmicosin. Vet Rec. 2006 Aug 5;159(6):163.
  • PMID: 12807303
    Von Essen S, Spencer J, Hass B, List P, Seifert SA: Unintentional human exposure to tilmicosin (Micotil 300). J Toxicol Clin Toxicol. 2003;41(3):229-33.
  • PMID: 8116500
    Fodor L, Varga J, Gallowitsch F, Horvath-Papp I, Miklos G, Lajcsak A, Harmath A: Treatment of calf pneumonia with tilmicosin. Acta Vet Hung. 1993;41(1-2):41-9.
  • PMID: 2038809
    Schumann FJ, Janzen ED, McKinnon JJ: Prophylactic medication of feedlot calves with tilmicosin. Vet Rec. 1991 Mar 23;128(12):278-80.
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Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Micotil

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