Tiamulin

DB11468

small molecule vet_approved

Deskripsi

Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.

Struktur Molekul 2D

Berat 493.742
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

55 Data
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Tiamulin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Tiamulin.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Tiamulin.
Dicoumarol The risk or severity of bleeding can be increased when Tiamulin is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when Tiamulin is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when Tiamulin is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when Tiamulin is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when Tiamulin is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when Tiamulin is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when Tiamulin is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when Tiamulin is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when Tiamulin is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when Tiamulin is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when Tiamulin is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when Tiamulin is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when Tiamulin is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when Tiamulin is combined with (S)-Warfarin.
Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Tiamulin.
Vibrio cholerae CVD 103-HgR strain live antigen The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Tiamulin.
Estetrol The therapeutic efficacy of Estetrol can be decreased when used in combination with Tiamulin.
Lidocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Quinisocaine.
Cisatracurium Tiamulin may increase the neuromuscular blocking activities of Cisatracurium.
Ambroxol The risk or severity of methemoglobinemia can be increased when Tiamulin is combined with Ambroxol.
Fecal microbiota The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with Tiamulin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 3686511
    Bouwkamp FT: Tiamulin: a dangerous drug?. Tijdschr Diergeneeskd. 1987 Nov 15;112(22):1295-6.
  • PMID: 7233787
    Miller DJ: Monensin-tiamulin interaction. Vet Rec. 1981 Apr 4;108(14):317-8.
  • PMID: 3952946
    Miller DJ, O'Connor JJ, Roberts NL: Tiamulin/salinomycin interactions in pigs. Vet Rec. 1986 Jan 18;118(3):73-5.
  • PMID: 19060324
    Burch DG: Tiamulin activity against Brachyspira hyodysenteriae. Vet Rec. 2008 Dec 6;163(23):698; author reply 698.
  • PMID: 7340095
    Pott JM, Shov B: Monensin--tiamulin interactions in pigs. Vet Rec. 1981 Dec 12;109(24):545.
  • PMID: 19103625
    Burch DG: Tiamulin activity against Brachyspira hyodysenteriae. Vet Rec. 2008 Dec 20-27;163(25):760.
  • PMID: 6854730
    Ziv G, Levisohn SL, Bar-Moshe B, Bor A, Soback S: Clinical pharmacology of tiamulin in ruminants. J Vet Pharmacol Ther. 1983 Mar;6(1):23-32.
  • PMID: 6505670
    Wanner M: Tiamulin and salinomycin intolerance in swine. Schweiz Arch Tierheilkd. 1984 Oct;126(10):521-6.
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