Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma. In the United States, it is currently approved for its veterinary use in dogs and distributed by Pfizer Animal Health. In Canada, medetomidine is distributed by Novartis Animal Health. The marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Medetomidine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Medetomidine may decrease the antihypertensive activities of Ramipril. |
| Remikiren | Medetomidine may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Medetomidine may decrease the antihypertensive activities of Torasemide. |
| Isradipine | Medetomidine may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Medetomidine may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Medetomidine may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Medetomidine may decrease the antihypertensive activities of Nitroprusside. |
| Diltiazem | Medetomidine may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Medetomidine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Medetomidine may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Medetomidine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Medetomidine may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Medetomidine may decrease the antihypertensive activities of Nisoldipine. |
| Bendroflumethiazide | Medetomidine may decrease the antihypertensive activities of Bendroflumethiazide. |
| Fosinopril | Medetomidine may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Medetomidine may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Medetomidine may decrease the antihypertensive activities of Metolazone. |
| Lercanidipine | Medetomidine may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Medetomidine may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Medetomidine may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Medetomidine may decrease the antihypertensive activities of Enalapril. |
| Cyclothiazide | Medetomidine may decrease the antihypertensive activities of Cyclothiazide. |
| Candoxatril | Medetomidine may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Medetomidine may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Medetomidine may decrease the antihypertensive activities of Losartan. |
| Moexipril | Medetomidine may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Medetomidine may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Medetomidine may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Medetomidine may decrease the antihypertensive activities of Nitroglycerin. |
| Hydroflumethiazide | Medetomidine may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Medetomidine may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Medetomidine may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Medetomidine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Medetomidine may decrease the antihypertensive activities of Fenoldopam. |
| Indapamide | Medetomidine may decrease the antihypertensive activities of Indapamide. |
| Tadalafil | Medetomidine may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Medetomidine may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Medetomidine may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Medetomidine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Medetomidine may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Medetomidine may decrease the antihypertensive activities of Methyldopa. |
| Hydrochlorothiazide | Medetomidine may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Medetomidine may decrease the antihypertensive activities of Trichlormethiazide. |
| Irbesartan | Medetomidine may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Medetomidine may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Medetomidine may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Medetomidine may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Medetomidine may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Medetomidine may decrease the antihypertensive activities of Diazoxide. |
| Captopril | Medetomidine may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Medetomidine may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Medetomidine may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Medetomidine may decrease the antihypertensive activities of Hydralazine. |
| Polythiazide | Medetomidine may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Medetomidine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Medetomidine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Medetomidine may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Medetomidine may decrease the antihypertensive activities of Mibefradil. |
| Tienilic acid | Medetomidine may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Medetomidine may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Medetomidine may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Medetomidine may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Medetomidine may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Medetomidine may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Medetomidine may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Medetomidine may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Medetomidine may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Medetomidine may decrease the antihypertensive activities of Macitentan. |
| Aliskiren | Medetomidine may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Medetomidine may decrease the antihypertensive activities of Nicorandil. |
| Efonidipine | Medetomidine may decrease the antihypertensive activities of Efonidipine. |
| Lacidipine | Medetomidine may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Medetomidine may decrease the antihypertensive activities of Manidipine. |
| Rauwolfia serpentina root | Medetomidine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Medetomidine may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Medetomidine may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Medetomidine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Medetomidine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Medetomidine may decrease the antihypertensive activities of BQ-123. |
| Cicletanine | Medetomidine may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Medetomidine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Medetomidine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Medetomidine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Medetomidine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Medetomidine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Medetomidine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Medetomidine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Medetomidine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Medetomidine may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Medetomidine may decrease the antihypertensive activities of Cadralazine. |
| Cyclopenthiazide | Medetomidine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Bietaserpine | Medetomidine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Medetomidine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Medetomidine may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Medetomidine may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Medetomidine may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Medetomidine may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Medetomidine may decrease the antihypertensive activities of Candesartan. |
| Dexniguldipine | Medetomidine may decrease the antihypertensive activities of Dexniguldipine. |