Fenthion

DB11412

small molecule vet_approved

Deskripsi

Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and animals.

Struktur Molekul 2D

Berat 278.328
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

605 Data
Dipyridamole The therapeutic efficacy of Fenthion can be decreased when used in combination with Dipyridamole.
Ephedrine Fenthion may increase the neuromuscular blocking activities of Ephedrine.
Bambuterol Fenthion may increase the neuromuscular blocking activities of Bambuterol.
Clevidipine Fenthion may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Fenthion may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Mirabegron Fenthion may increase the neuromuscular blocking activities of Mirabegron.
Moxisylyte Fenthion may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Fenthion may increase the neuromuscular blocking activities of Propacetamol.
Procaine Fenthion may increase the neuromuscular blocking activities of Procaine.
Cocaine Fenthion may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Fenthion may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Fenthion may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Fenthion may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Fenthion may increase the neuromuscular blocking activities of Tubocurarine.
Aclidinium Fenthion may increase the neuromuscular blocking activities of Aclidinium.
Butyrylthiocholine Fenthion may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Fenthion may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Fenthion may increase the neuromuscular blocking activities of Benzonatate.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Fenthion.
Tramadol The therapeutic efficacy of Tramadol can be decreased when used in combination with Fenthion.
Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Fenthion.
Oxyphenonium The therapeutic efficacy of Oxyphenonium can be decreased when used in combination with Fenthion.
Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Fenthion.
Butalbital The therapeutic efficacy of Butalbital can be decreased when used in combination with Fenthion.
Talbutal The therapeutic efficacy of Talbutal can be decreased when used in combination with Fenthion.
Pentobarbital The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Fenthion.
Ipratropium The therapeutic efficacy of Ipratropium can be decreased when used in combination with Fenthion.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Fenthion.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Fenthion.
Oxyphencyclimine The therapeutic efficacy of Oxyphencyclimine can be decreased when used in combination with Fenthion.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Fenthion.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Fenthion.
Secobarbital The therapeutic efficacy of Secobarbital can be decreased when used in combination with Fenthion.
Methscopolamine bromide The therapeutic efficacy of Methscopolamine bromide can be decreased when used in combination with Fenthion.
Metharbital The therapeutic efficacy of Metharbital can be decreased when used in combination with Fenthion.
Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Fenthion.
Tridihexethyl The therapeutic efficacy of Tridihexethyl can be decreased when used in combination with Fenthion.
Triflupromazine The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Fenthion.
Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Fenthion.
Anisotropine methylbromide The therapeutic efficacy of Anisotropine methylbromide can be decreased when used in combination with Fenthion.
Thiopental The therapeutic efficacy of Thiopental can be decreased when used in combination with Fenthion.
Mecamylamine The therapeutic efficacy of Mecamylamine can be decreased when used in combination with Fenthion.
Pirenzepine The therapeutic efficacy of Pirenzepine can be decreased when used in combination with Fenthion.
Paroxetine The therapeutic efficacy of Paroxetine can be decreased when used in combination with Fenthion.
Homatropine methylbromide The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Fenthion.
Scopolamine The therapeutic efficacy of Scopolamine can be decreased when used in combination with Fenthion.
Benzquinamide The therapeutic efficacy of Benzquinamide can be decreased when used in combination with Fenthion.
Clidinium The therapeutic efficacy of Clidinium can be decreased when used in combination with Fenthion.
Propiomazine The therapeutic efficacy of Propiomazine can be decreased when used in combination with Fenthion.
Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Fenthion.
Primidone The therapeutic efficacy of Primidone can be decreased when used in combination with Fenthion.
Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Fenthion.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Fenthion.
Methylphenobarbital The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Fenthion.
Methantheline The therapeutic efficacy of Methantheline can be decreased when used in combination with Fenthion.
Hexafluronium The therapeutic efficacy of Hexafluronium can be decreased when used in combination with Fenthion.
Cycrimine The therapeutic efficacy of Cycrimine can be decreased when used in combination with Fenthion.
Glycopyrronium The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Fenthion.
Oxybutynin The therapeutic efficacy of Oxybutynin can be decreased when used in combination with Fenthion.
Pentolinium The therapeutic efficacy of Pentolinium can be decreased when used in combination with Fenthion.
Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Fenthion.
Phenobarbital The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Fenthion.
Diphenidol The therapeutic efficacy of Diphenidol can be decreased when used in combination with Fenthion.
Fenoterol The therapeutic efficacy of Fenoterol can be decreased when used in combination with Fenthion.
Amobarbital The therapeutic efficacy of Amobarbital can be decreased when used in combination with Fenthion.
Aprobarbital The therapeutic efficacy of Aprobarbital can be decreased when used in combination with Fenthion.
Butobarbital The therapeutic efficacy of Butobarbital can be decreased when used in combination with Fenthion.
Heptabarbital The therapeutic efficacy of Heptabarbital can be decreased when used in combination with Fenthion.
Hexobarbital The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Fenthion.
Tiotropium The therapeutic efficacy of Tiotropium can be decreased when used in combination with Fenthion.
Barbital The therapeutic efficacy of Barbital can be decreased when used in combination with Fenthion.
Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione The therapeutic efficacy of Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione can be decreased when used in combination with Fenthion.
Isopropamide The therapeutic efficacy of Isopropamide can be decreased when used in combination with Fenthion.
Mepenzolate The therapeutic efficacy of Mepenzolate can be decreased when used in combination with Fenthion.
Gantacurium The therapeutic efficacy of Gantacurium can be decreased when used in combination with Fenthion.
Pizotifen The therapeutic efficacy of Pizotifen can be decreased when used in combination with Fenthion.
Fesoterodine The therapeutic efficacy of Fesoterodine can be decreased when used in combination with Fenthion.
Hexocyclium The therapeutic efficacy of Hexocyclium can be decreased when used in combination with Fenthion.
Dimetindene The therapeutic efficacy of Dimetindene can be decreased when used in combination with Fenthion.
Agmatine The therapeutic efficacy of Agmatine can be decreased when used in combination with Fenthion.
Hexamethonium The therapeutic efficacy of Hexamethonium can be decreased when used in combination with Fenthion.
Dexetimide The therapeutic efficacy of Dexetimide can be decreased when used in combination with Fenthion.
Benactyzine The therapeutic efficacy of Benactyzine can be decreased when used in combination with Fenthion.
Umeclidinium The therapeutic efficacy of Umeclidinium can be decreased when used in combination with Fenthion.
Imidafenacin The therapeutic efficacy of Imidafenacin can be decreased when used in combination with Fenthion.
Butylscopolamine The therapeutic efficacy of Butylscopolamine can be decreased when used in combination with Fenthion.
Thonzylamine The therapeutic efficacy of Thonzylamine can be decreased when used in combination with Fenthion.
Methscopolamine The therapeutic efficacy of Methscopolamine can be decreased when used in combination with Fenthion.
Revefenacin The therapeutic efficacy of Revefenacin can be decreased when used in combination with Fenthion.
Oxitropium The therapeutic efficacy of Oxitropium can be decreased when used in combination with Fenthion.
Propiverine The therapeutic efficacy of Propiverine can be decreased when used in combination with Fenthion.
Batefenterol The therapeutic efficacy of Batefenterol can be decreased when used in combination with Fenthion.
Mebeverine The therapeutic efficacy of Mebeverine can be decreased when used in combination with Fenthion.
Tropatepine The therapeutic efficacy of Tropatepine can be decreased when used in combination with Fenthion.
Prifinium The therapeutic efficacy of Prifinium can be decreased when used in combination with Fenthion.
Piperidolate The therapeutic efficacy of Piperidolate can be decreased when used in combination with Fenthion.
Benzilone The therapeutic efficacy of Benzilone can be decreased when used in combination with Fenthion.
Difemerine The therapeutic efficacy of Difemerine can be decreased when used in combination with Fenthion.
Phenglutarimide The therapeutic efficacy of Phenglutarimide can be decreased when used in combination with Fenthion.
Mazaticol The therapeutic efficacy of Mazaticol can be decreased when used in combination with Fenthion.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 2706349
    Wang T, Kadlac T, Lenahan R: Persistence of fenthion in the aquatic environment. Bull Environ Contam Toxicol. 1989 Mar;42(3):389-94.
  • PMID: 10509433
    Tuler SM, Bowen JM: Chronic fenthion toxicity in laying hens. Vet Hum Toxicol. 1999 Oct;41(5):302-7.
  • PMID: 11048676
    Kitamura S, Kadota T, Yoshida M, Jinno N, Ohta S: Whole-body metabolism of the organophosphorus pesticide, fenthion, in goldfish, Carassius auratus. Comp Biochem Physiol C Toxicol Pharmacol. 2000 Jul;126(3):259-66.
  • PMID: 18558709
    Amvrazi EG, Albanis TA: Multiclass pesticide determination in olives and their processing factors in olive oil: comparison of different olive oil extraction systems. J Agric Food Chem. 2008 Jul 23;56(14):5700-9. doi: 10.1021/jf703783u. Epub 2008 Jun 18.
  • PMID: 3183857
    Wadia RS, Amin RB: Fenthion poisoning. J Pediatr. 1988 Nov;113(5):950.
  • PMID: 3411415
    Mortensen ME: Therapy for fenthion poisoning. J Pediatr. 1988 Sep;113(3):616-7.
  • PMID: 5074266
    Authors unspecified: Fenthion--and heartworm disease. J Am Vet Med Assoc. 1972 Oct 15;161(8):870.
  • PMID: 7253093
    Zinkl JG, Jessup DA, Bischoff AI, Lew TE, Wheeldon EB: Fenthion poisoning of wading birds. J Wildl Dis. 1981 Jan;17(1):117-9.
Menampilkan 8 dari 12 artikel.
Textbook
  • ISBN: 1584884169
    Yannai, Shmuel (2003). Dictionary of Food Compounds with : Additives, Flavors, and Ingredients. CRC Press LLC.

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