Enrofloxacin

DB11404

small molecule vet_approved

Deskripsi

Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of Campylobacter, in September 2005, the FDA withdrew the approval of enrofloxacin for its use in water to treat flocks of poultry.

Struktur Molekul 2D

Berat 359.3947
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

618 Data
Didanosine Didanosine can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Probenecid Probenecid may decrease the excretion rate of Enrofloxacin which could result in a higher serum level.
Quinapril Quinapril can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate Calcium acetate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron Dextran Iron Dextran can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium Calcium can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium carbonate Calcium carbonate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum carbonate Lanthanum carbonate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric carboxymaltose Ferric carboxymaltose can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Iron sucrose Iron sucrose can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric pyrophosphate Ferric pyrophosphate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium citrate Calcium citrate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium gluconate Calcium gluconate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric sulfate Ferric sulfate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric cation Ferric cation can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Tetraferric tricitrate decahydrate Tetraferric tricitrate decahydrate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lanthanum III cation Lanthanum III cation can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium polycarbophil Calcium polycarbophil can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ferric oxyhydroxide Ferric oxyhydroxide can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sucralfate Sucralfate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Enrofloxacin.
Nitrofurantoin The therapeutic efficacy of Enrofloxacin can be decreased when used in combination with Nitrofurantoin.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Enrofloxacin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Enrofloxacin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Enrofloxacin.
Insulin human The therapeutic efficacy of Insulin human can be increased when used in combination with Enrofloxacin.
Insulin lispro The therapeutic efficacy of Insulin lispro can be increased when used in combination with Enrofloxacin.
Insulin pork The therapeutic efficacy of Insulin pork can be increased when used in combination with Enrofloxacin.
Troglitazone The therapeutic efficacy of Troglitazone can be increased when used in combination with Enrofloxacin.
Glimepiride The therapeutic efficacy of Glimepiride can be increased when used in combination with Enrofloxacin.
Sulfisoxazole The therapeutic efficacy of Sulfisoxazole can be increased when used in combination with Enrofloxacin.
Disopyramide The therapeutic efficacy of Disopyramide can be increased when used in combination with Enrofloxacin.
Acarbose The therapeutic efficacy of Acarbose can be increased when used in combination with Enrofloxacin.
Metformin The therapeutic efficacy of Metformin can be increased when used in combination with Enrofloxacin.
Sulfadiazine The therapeutic efficacy of Sulfadiazine can be increased when used in combination with Enrofloxacin.
Rosiglitazone The therapeutic efficacy of Rosiglitazone can be increased when used in combination with Enrofloxacin.
Acetohexamide The therapeutic efficacy of Acetohexamide can be increased when used in combination with Enrofloxacin.
Quinine The therapeutic efficacy of Quinine can be increased when used in combination with Enrofloxacin.
Miglitol The therapeutic efficacy of Miglitol can be increased when used in combination with Enrofloxacin.
Chlorpropamide The therapeutic efficacy of Chlorpropamide can be increased when used in combination with Enrofloxacin.
Nateglinide The therapeutic efficacy of Nateglinide can be increased when used in combination with Enrofloxacin.
Pentamidine The therapeutic efficacy of Pentamidine can be increased when used in combination with Enrofloxacin.
Mifepristone The therapeutic efficacy of Mifepristone can be increased when used in combination with Enrofloxacin.
Tolazamide The therapeutic efficacy of Tolazamide can be increased when used in combination with Enrofloxacin.
Repaglinide The therapeutic efficacy of Repaglinide can be increased when used in combination with Enrofloxacin.
Phenformin The therapeutic efficacy of Phenformin can be increased when used in combination with Enrofloxacin.
Sulfamethoxazole The therapeutic efficacy of Sulfamethoxazole can be increased when used in combination with Enrofloxacin.
Glyburide The therapeutic efficacy of Glyburide can be increased when used in combination with Enrofloxacin.
Glipizide The therapeutic efficacy of Glipizide can be increased when used in combination with Enrofloxacin.
Gliclazide The therapeutic efficacy of Gliclazide can be increased when used in combination with Enrofloxacin.
Tolbutamide The therapeutic efficacy of Tolbutamide can be increased when used in combination with Enrofloxacin.
Pioglitazone The therapeutic efficacy of Pioglitazone can be increased when used in combination with Enrofloxacin.
Bromocriptine The therapeutic efficacy of Bromocriptine can be increased when used in combination with Enrofloxacin.
Gliquidone The therapeutic efficacy of Gliquidone can be increased when used in combination with Enrofloxacin.
Mitiglinide The therapeutic efficacy of Mitiglinide can be increased when used in combination with Enrofloxacin.
Sitagliptin The therapeutic efficacy of Sitagliptin can be increased when used in combination with Enrofloxacin.
Sunitinib The therapeutic efficacy of Sunitinib can be increased when used in combination with Enrofloxacin.
Exenatide The therapeutic efficacy of Exenatide can be increased when used in combination with Enrofloxacin.
Mecasermin The therapeutic efficacy of Mecasermin can be increased when used in combination with Enrofloxacin.
Pramlintide The therapeutic efficacy of Pramlintide can be increased when used in combination with Enrofloxacin.
Glisoxepide The therapeutic efficacy of Glisoxepide can be increased when used in combination with Enrofloxacin.
Insulin aspart The therapeutic efficacy of Insulin aspart can be increased when used in combination with Enrofloxacin.
Insulin glulisine The therapeutic efficacy of Insulin glulisine can be increased when used in combination with Enrofloxacin.
Glymidine The therapeutic efficacy of Glymidine can be increased when used in combination with Enrofloxacin.
AICA ribonucleotide The therapeutic efficacy of AICA ribonucleotide can be increased when used in combination with Enrofloxacin.
Buformin The therapeutic efficacy of Buformin can be increased when used in combination with Enrofloxacin.
Vildagliptin The therapeutic efficacy of Vildagliptin can be increased when used in combination with Enrofloxacin.
Voglibose The therapeutic efficacy of Voglibose can be increased when used in combination with Enrofloxacin.
NN344 The therapeutic efficacy of NN344 can be increased when used in combination with Enrofloxacin.
AMG-222 The therapeutic efficacy of AMG-222 can be increased when used in combination with Enrofloxacin.
Bisegliptin The therapeutic efficacy of Bisegliptin can be increased when used in combination with Enrofloxacin.
Alogliptin The therapeutic efficacy of Alogliptin can be increased when used in combination with Enrofloxacin.
Dapagliflozin The therapeutic efficacy of Dapagliflozin can be increased when used in combination with Enrofloxacin.
Saxagliptin The therapeutic efficacy of Saxagliptin can be increased when used in combination with Enrofloxacin.
Liraglutide The therapeutic efficacy of Liraglutide can be increased when used in combination with Enrofloxacin.
Gosogliptin The therapeutic efficacy of Gosogliptin can be increased when used in combination with Enrofloxacin.
Linagliptin The therapeutic efficacy of Linagliptin can be increased when used in combination with Enrofloxacin.
Canagliflozin The therapeutic efficacy of Canagliflozin can be increased when used in combination with Enrofloxacin.
Glibornuride The therapeutic efficacy of Glibornuride can be increased when used in combination with Enrofloxacin.
Benfluorex The therapeutic efficacy of Benfluorex can be increased when used in combination with Enrofloxacin.
Empagliflozin The therapeutic efficacy of Empagliflozin can be increased when used in combination with Enrofloxacin.
Albiglutide The therapeutic efficacy of Albiglutide can be increased when used in combination with Enrofloxacin.
Dulaglutide The therapeutic efficacy of Dulaglutide can be increased when used in combination with Enrofloxacin.
Lobeglitazone The therapeutic efficacy of Lobeglitazone can be increased when used in combination with Enrofloxacin.
Netoglitazone The therapeutic efficacy of Netoglitazone can be increased when used in combination with Enrofloxacin.
Rivoglitazone The therapeutic efficacy of Rivoglitazone can be increased when used in combination with Enrofloxacin.
Ciglitazone The therapeutic efficacy of Ciglitazone can be increased when used in combination with Enrofloxacin.
Lixisenatide The therapeutic efficacy of Lixisenatide can be increased when used in combination with Enrofloxacin.
Insulin beef The therapeutic efficacy of Insulin beef can be increased when used in combination with Enrofloxacin.
Insulin degludec The therapeutic efficacy of Insulin degludec can be increased when used in combination with Enrofloxacin.
Insulin peglispro The therapeutic efficacy of Insulin peglispro can be increased when used in combination with Enrofloxacin.
Insulin tregopil The therapeutic efficacy of Insulin tregopil can be increased when used in combination with Enrofloxacin.
Ipragliflozin The therapeutic efficacy of Ipragliflozin can be increased when used in combination with Enrofloxacin.
Dutogliptin The therapeutic efficacy of Dutogliptin can be increased when used in combination with Enrofloxacin.
Allicin The therapeutic efficacy of Allicin can be increased when used in combination with Enrofloxacin.
Tofogliflozin The therapeutic efficacy of Tofogliflozin can be increased when used in combination with Enrofloxacin.
Ertugliflozin The therapeutic efficacy of Ertugliflozin can be increased when used in combination with Enrofloxacin.
2,4-thiazolidinedione The therapeutic efficacy of 2,4-thiazolidinedione can be increased when used in combination with Enrofloxacin.
Teneligliptin The therapeutic efficacy of Teneligliptin can be increased when used in combination with Enrofloxacin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 8393228
    Dick GC: Use of enrofloxacin. Vet Rec. 1993 Jun 12;132(24):616.
  • PMID: 9278889
    Lizondo M, Pons M, Gallardo M, Estelrich J: Physicochemical properties of enrofloxacin. J Pharm Biomed Anal. 1997 Aug;15(12):1845-9.
  • PMID: 1926748
    Bowser PR, Babish JG: Enrofloxacin in salmonids. Vet Hum Toxicol. 1991;33 Suppl 1:46-8.
  • PMID: 12049983
    e Souza MJ, Bittencourt CF, Morsch LM: LC determination of enrofloxacin. J Pharm Biomed Anal. 2002 Jun 15;28(6):1195-9.
  • PMID: 16964946
    Wu Y, Liao X, Wang Z, Chen Z, Zhou Y: Hydrolysis characteristics of enrofloxacin. Ying Yong Sheng Tai Xue Bao. 2006 Jun;17(6):1086-90.
  • PMID: 15129996
    e Souza MJ, Bittencourt CF, e Souza Filho Pda S: Microbiological assay for enrofloxacin injection. Int J Pharm. 2004 Mar 1;271(1-2):287-91.
  • PMID: 9511011
    Kan CA: Pharmacokinetics of enrofloxacin in chicken. Br Poult Sci. 1997 Dec;38(5):614.
  • PMID: 17107697
    Dimitrova DJ, Lashev LD, Yanev SG, Pandova B: Pharmacokinetics of enrofloxacin in turkeys. Res Vet Sci. 2007 Jun;82(3):392-7. Epub 2006 Nov 14.
Menampilkan 8 dari 16 artikel.
Textbook
  • ISBN: 1584884169
    Yannai, Shmuel (2003). Dictionary of Food Compounds with : Additives, Flavors, and Ingredients. CRC Press LLC.

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