Efrotomycin

DB11401

small molecule vet_approved

Deskripsi

Struktur Molekul 2D

Berat 1145.347
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

55 Data
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Efrotomycin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Efrotomycin.
Typhoid vaccine The therapeutic efficacy of Typhoid vaccine can be decreased when used in combination with Efrotomycin.
Dicoumarol The risk or severity of bleeding can be increased when Efrotomycin is combined with Dicoumarol.
Phenindione The risk or severity of bleeding can be increased when Efrotomycin is combined with Phenindione.
Warfarin The risk or severity of bleeding can be increased when Efrotomycin is combined with Warfarin.
Phenprocoumon The risk or severity of bleeding can be increased when Efrotomycin is combined with Phenprocoumon.
Acenocoumarol The risk or severity of bleeding can be increased when Efrotomycin is combined with Acenocoumarol.
4-hydroxycoumarin The risk or severity of bleeding can be increased when Efrotomycin is combined with 4-hydroxycoumarin.
Coumarin The risk or severity of bleeding can be increased when Efrotomycin is combined with Coumarin.
(R)-warfarin The risk or severity of bleeding can be increased when Efrotomycin is combined with (R)-warfarin.
Ethyl biscoumacetate The risk or severity of bleeding can be increased when Efrotomycin is combined with Ethyl biscoumacetate.
Fluindione The risk or severity of bleeding can be increased when Efrotomycin is combined with Fluindione.
Clorindione The risk or severity of bleeding can be increased when Efrotomycin is combined with Clorindione.
Diphenadione The risk or severity of bleeding can be increased when Efrotomycin is combined with Diphenadione.
Tioclomarol The risk or severity of bleeding can be increased when Efrotomycin is combined with Tioclomarol.
(S)-Warfarin The risk or severity of bleeding can be increased when Efrotomycin is combined with (S)-Warfarin.
Lactulose The therapeutic efficacy of Lactulose can be decreased when used in combination with Efrotomycin.
Vibrio cholerae CVD 103-HgR strain live antigen The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Efrotomycin.
Estetrol The therapeutic efficacy of Estetrol can be decreased when used in combination with Efrotomycin.
Lidocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Lidocaine.
Ropivacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Ropivacaine.
Bupivacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Bupivacaine.
Cinchocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Cinchocaine.
Dyclonine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Dyclonine.
Procaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Procaine.
Prilocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Prilocaine.
Proparacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Proparacaine.
Meloxicam The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Meloxicam.
Oxybuprocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Oxybuprocaine.
Cocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Cocaine.
Mepivacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Mepivacaine.
Levobupivacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Levobupivacaine.
Diphenhydramine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Diphenhydramine.
Benzocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Benzocaine.
Chloroprocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Chloroprocaine.
Phenol The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Phenol.
Tetrodotoxin The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Tetrodotoxin.
Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Benzyl alcohol.
Capsaicin The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Capsaicin.
Etidocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Etidocaine.
Articaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Articaine.
Tetracaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Tetracaine.
Propoxycaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Propoxycaine.
Pramocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Pramocaine.
Butamben The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Butamben.
Butacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Butacaine.
Oxetacaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Oxetacaine.
Ethyl chloride The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Ethyl chloride.
Butanilicaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Butanilicaine.
Metabutethamine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Metabutethamine.
Quinisocaine The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Quinisocaine.
Cisatracurium Efrotomycin may increase the neuromuscular blocking activities of Cisatracurium.
Ambroxol The risk or severity of methemoglobinemia can be increased when Efrotomycin is combined with Ambroxol.
Fecal microbiota The therapeutic efficacy of Fecal microbiota can be decreased when used in combination with Efrotomycin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 994327
    Frost BM, Valiant ME, Weissberger B, Dulaney EL: Antibacterial activity of efrotomycin. J Antibiot (Tokyo). 1976 Oct;29(10):1083-91.
  • PMID: 528364
    Frost BM, Valiant ME, Dulaney EL: Synergism between efrotomycin and bottromycin. J Antibiot (Tokyo). 1979 Oct;32(10):1046-9.
  • PMID: 950325
    Wax R, Maises W, Weston R, Birnbaum J: Efrotomycin, a new antibiotic from Streptomyces lactamdurans. J Antibiot (Tokyo). 1976 Jun;29(6):670-3.
  • PMID: 2737954
    Nielsen JB, Kaplan L: A resting cell system for efrotomycin biosynthesis. J Antibiot (Tokyo). 1989 Jun;42(6):944-51.
  • PMID: 3752528
    Stong JD: Determination of efrotomycin in feeds by high-performance liquid chromatography. Analyst. 1986 Jul;111(7):853-5.
  • PMID: 1367328
    Chartrain M, Hunt G, Horn L, Kirpekar A, Mathre D, Powell A, Wassel L, Nielsen J, Buckland B, Greasham R: Biochemical and physiological characterization of the efrotomycin fermentation. J Ind Microbiol. 1991 Jun;7(4):293-9.
  • PMID: 1367205
    Cover WH, Kirpekar AC, George H, Stieber RW: Calcium inhibition of efrotomycin production by Nocardia lactamdurans. J Ind Microbiol. 1991 Jan;7(1):41-4.
  • PMID: 1367801
    Darland G, Arison B, Kaplan L: The biosynthetic origin of the pyridone ring of efrotomycin. J Ind Microbiol. 1991 Nov;8(4):265-71.
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