Dichlorvos

DB11397

small molecule vet_approved

Deskripsi

Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic due to environmental and health concerns. Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity, and cancer.

Struktur Molekul 2D

Berat 220.976
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

605 Data
Dipyridamole The therapeutic efficacy of Dichlorvos can be decreased when used in combination with Dipyridamole.
Ephedrine Dichlorvos may increase the neuromuscular blocking activities of Ephedrine.
Bambuterol Dichlorvos may increase the neuromuscular blocking activities of Bambuterol.
Clevidipine Dichlorvos may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Dichlorvos may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Mirabegron Dichlorvos may increase the neuromuscular blocking activities of Mirabegron.
Moxisylyte Dichlorvos may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Dichlorvos may increase the neuromuscular blocking activities of Propacetamol.
Procaine Dichlorvos may increase the neuromuscular blocking activities of Procaine.
Cocaine Dichlorvos may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Dichlorvos may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Dichlorvos may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Dichlorvos may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Dichlorvos may increase the neuromuscular blocking activities of Tubocurarine.
Aclidinium Dichlorvos may increase the neuromuscular blocking activities of Aclidinium.
Butyrylthiocholine Dichlorvos may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Dichlorvos may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Dichlorvos may increase the neuromuscular blocking activities of Benzonatate.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Dichlorvos.
Tramadol The therapeutic efficacy of Tramadol can be decreased when used in combination with Dichlorvos.
Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Dichlorvos.
Oxyphenonium The therapeutic efficacy of Oxyphenonium can be decreased when used in combination with Dichlorvos.
Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Dichlorvos.
Butalbital The therapeutic efficacy of Butalbital can be decreased when used in combination with Dichlorvos.
Talbutal The therapeutic efficacy of Talbutal can be decreased when used in combination with Dichlorvos.
Pentobarbital The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Dichlorvos.
Ipratropium The therapeutic efficacy of Ipratropium can be decreased when used in combination with Dichlorvos.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Dichlorvos.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Dichlorvos.
Oxyphencyclimine The therapeutic efficacy of Oxyphencyclimine can be decreased when used in combination with Dichlorvos.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Dichlorvos.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Dichlorvos.
Secobarbital The therapeutic efficacy of Secobarbital can be decreased when used in combination with Dichlorvos.
Methscopolamine bromide The therapeutic efficacy of Methscopolamine bromide can be decreased when used in combination with Dichlorvos.
Metharbital The therapeutic efficacy of Metharbital can be decreased when used in combination with Dichlorvos.
Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Dichlorvos.
Tridihexethyl The therapeutic efficacy of Tridihexethyl can be decreased when used in combination with Dichlorvos.
Triflupromazine The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Dichlorvos.
Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Dichlorvos.
Anisotropine methylbromide The therapeutic efficacy of Anisotropine methylbromide can be decreased when used in combination with Dichlorvos.
Thiopental The therapeutic efficacy of Thiopental can be decreased when used in combination with Dichlorvos.
Mecamylamine The therapeutic efficacy of Mecamylamine can be decreased when used in combination with Dichlorvos.
Pirenzepine The therapeutic efficacy of Pirenzepine can be decreased when used in combination with Dichlorvos.
Paroxetine The therapeutic efficacy of Paroxetine can be decreased when used in combination with Dichlorvos.
Homatropine methylbromide The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Dichlorvos.
Scopolamine The therapeutic efficacy of Scopolamine can be decreased when used in combination with Dichlorvos.
Benzquinamide The therapeutic efficacy of Benzquinamide can be decreased when used in combination with Dichlorvos.
Clidinium The therapeutic efficacy of Clidinium can be decreased when used in combination with Dichlorvos.
Propiomazine The therapeutic efficacy of Propiomazine can be decreased when used in combination with Dichlorvos.
Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Dichlorvos.
Primidone The therapeutic efficacy of Primidone can be decreased when used in combination with Dichlorvos.
Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Dichlorvos.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Dichlorvos.
Methylphenobarbital The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Dichlorvos.
Methantheline The therapeutic efficacy of Methantheline can be decreased when used in combination with Dichlorvos.
Hexafluronium The therapeutic efficacy of Hexafluronium can be decreased when used in combination with Dichlorvos.
Cycrimine The therapeutic efficacy of Cycrimine can be decreased when used in combination with Dichlorvos.
Glycopyrronium The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Dichlorvos.
Oxybutynin The therapeutic efficacy of Oxybutynin can be decreased when used in combination with Dichlorvos.
Pentolinium The therapeutic efficacy of Pentolinium can be decreased when used in combination with Dichlorvos.
Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Dichlorvos.
Phenobarbital The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Dichlorvos.
Diphenidol The therapeutic efficacy of Diphenidol can be decreased when used in combination with Dichlorvos.
Fenoterol The therapeutic efficacy of Fenoterol can be decreased when used in combination with Dichlorvos.
Amobarbital The therapeutic efficacy of Amobarbital can be decreased when used in combination with Dichlorvos.
Aprobarbital The therapeutic efficacy of Aprobarbital can be decreased when used in combination with Dichlorvos.
Butobarbital The therapeutic efficacy of Butobarbital can be decreased when used in combination with Dichlorvos.
Heptabarbital The therapeutic efficacy of Heptabarbital can be decreased when used in combination with Dichlorvos.
Hexobarbital The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Dichlorvos.
Tiotropium The therapeutic efficacy of Tiotropium can be decreased when used in combination with Dichlorvos.
Barbital The therapeutic efficacy of Barbital can be decreased when used in combination with Dichlorvos.
Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione The therapeutic efficacy of Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione can be decreased when used in combination with Dichlorvos.
Isopropamide The therapeutic efficacy of Isopropamide can be decreased when used in combination with Dichlorvos.
Mepenzolate The therapeutic efficacy of Mepenzolate can be decreased when used in combination with Dichlorvos.
Gantacurium The therapeutic efficacy of Gantacurium can be decreased when used in combination with Dichlorvos.
Pizotifen The therapeutic efficacy of Pizotifen can be decreased when used in combination with Dichlorvos.
Fesoterodine The therapeutic efficacy of Fesoterodine can be decreased when used in combination with Dichlorvos.
Hexocyclium The therapeutic efficacy of Hexocyclium can be decreased when used in combination with Dichlorvos.
Dimetindene The therapeutic efficacy of Dimetindene can be decreased when used in combination with Dichlorvos.
Agmatine The therapeutic efficacy of Agmatine can be decreased when used in combination with Dichlorvos.
Hexamethonium The therapeutic efficacy of Hexamethonium can be decreased when used in combination with Dichlorvos.
Dexetimide The therapeutic efficacy of Dexetimide can be decreased when used in combination with Dichlorvos.
Benactyzine The therapeutic efficacy of Benactyzine can be decreased when used in combination with Dichlorvos.
Umeclidinium The therapeutic efficacy of Umeclidinium can be decreased when used in combination with Dichlorvos.
Imidafenacin The therapeutic efficacy of Imidafenacin can be decreased when used in combination with Dichlorvos.
Butylscopolamine The therapeutic efficacy of Butylscopolamine can be decreased when used in combination with Dichlorvos.
Thonzylamine The therapeutic efficacy of Thonzylamine can be decreased when used in combination with Dichlorvos.
Methscopolamine The therapeutic efficacy of Methscopolamine can be decreased when used in combination with Dichlorvos.
Revefenacin The therapeutic efficacy of Revefenacin can be decreased when used in combination with Dichlorvos.
Oxitropium The therapeutic efficacy of Oxitropium can be decreased when used in combination with Dichlorvos.
Propiverine The therapeutic efficacy of Propiverine can be decreased when used in combination with Dichlorvos.
Batefenterol The therapeutic efficacy of Batefenterol can be decreased when used in combination with Dichlorvos.
Mebeverine The therapeutic efficacy of Mebeverine can be decreased when used in combination with Dichlorvos.
Tropatepine The therapeutic efficacy of Tropatepine can be decreased when used in combination with Dichlorvos.
Prifinium The therapeutic efficacy of Prifinium can be decreased when used in combination with Dichlorvos.
Piperidolate The therapeutic efficacy of Piperidolate can be decreased when used in combination with Dichlorvos.
Benzilone The therapeutic efficacy of Benzilone can be decreased when used in combination with Dichlorvos.
Difemerine The therapeutic efficacy of Difemerine can be decreased when used in combination with Dichlorvos.
Phenglutarimide The therapeutic efficacy of Phenglutarimide can be decreased when used in combination with Dichlorvos.
Mazaticol The therapeutic efficacy of Mazaticol can be decreased when used in combination with Dichlorvos.

Target Protein

Serotransferrin TF
Cholinesterase BCHE

Referensi & Sumber

Artikel (PubMed)
  • PMID: 1842580
    Authors unspecified: Dichlorvos. IARC Monogr Eval Carcinog Risks Hum. 1991;53:267-307.
  • PMID: 397180
    Authors unspecified: Dichlorvos. IARC Monogr Eval Carcinog Risk Chem Hum. 1979 Oct;20:97-127.
  • PMID: 7344402
    Slomka MB, Hine CH: Clinical pharmacology of dichlorvos. Acta Pharmacol Toxicol (Copenh). 1981;49 Suppl 5:105-8.
  • PMID: 6730571
    Ellinger C: Is dichlorvos hepatotoxic?. Z Gesamte Hyg. 1984 Mar;30(3):156-8.
  • PMID: 5412228
    Fowler NG, Evans DA, Wickham RA: Dichlorvos horse anthelmintic. Vet Rec. 1970 Jan 24;86(4):106.
  • PMID: 7009035
    Reuber MD: Carcinogenicity of dichlorvos. Clin Toxicol. 1981 Jan;18(1):47-84.
  • PMID: 21405039
    Aschmann SM, Tuazon EC, Long WD, Atkinson R: Atmospheric chemistry of dichlorvos. J Phys Chem A. 2011 Apr 7;115(13):2756-64. doi: 10.1021/jp112019s. Epub 2011 Mar 15.
  • PMID: 4564322
    Ashwood-Smith MJ, Trevino J, Ring R: Mutagenicity of dichlorvos. Nature. 1972 Dec 15;240(5381):418-20.
Menampilkan 8 dari 15 artikel.
Textbook
  • ISBN: 1584884169
    Yannai, Shmuel (2003). Dictionary of Food Compounds with : Additives, Flavors, and Ingredients. CRC Press LLC.

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International Brands
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