Coumaphos

DB11390

small molecule vet_approved

Deskripsi

This drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a dip or wash. Coumaphos is widely used for both farm and domestic animals to control ticks, mites, flies and fleas.

Struktur Molekul 2D

Berat 362.766
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

622 Data
Dipyridamole The therapeutic efficacy of Coumaphos can be decreased when used in combination with Dipyridamole.
Ephedrine Coumaphos may increase the neuromuscular blocking activities of Ephedrine.
Bambuterol Coumaphos may increase the neuromuscular blocking activities of Bambuterol.
Clevidipine Coumaphos may increase the neuromuscular blocking activities of Clevidipine.
Sar9, Met (O2)11-Substance P Coumaphos may increase the neuromuscular blocking activities of Sar9, Met (O2)11-Substance P.
Mirabegron Coumaphos may increase the neuromuscular blocking activities of Mirabegron.
Moxisylyte Coumaphos may increase the neuromuscular blocking activities of Moxisylyte.
Propacetamol Coumaphos may increase the neuromuscular blocking activities of Propacetamol.
Procaine Coumaphos may increase the neuromuscular blocking activities of Procaine.
Cocaine Coumaphos may increase the neuromuscular blocking activities of Cocaine.
Trimethaphan Coumaphos may increase the neuromuscular blocking activities of Trimethaphan.
Doxacurium Coumaphos may increase the neuromuscular blocking activities of Doxacurium.
Chloroprocaine Coumaphos may increase the neuromuscular blocking activities of Chloroprocaine.
Tubocurarine Coumaphos may increase the neuromuscular blocking activities of Tubocurarine.
Aclidinium Coumaphos may increase the neuromuscular blocking activities of Aclidinium.
Butyrylthiocholine Coumaphos may increase the neuromuscular blocking activities of Butyrylthiocholine.
Oxybuprocaine Coumaphos may increase the neuromuscular blocking activities of Oxybuprocaine.
Benzonatate Coumaphos may increase the neuromuscular blocking activities of Benzonatate.
Succinylcholine The metabolism of Succinylcholine can be decreased when combined with Coumaphos.
Tramadol The therapeutic efficacy of Tramadol can be decreased when used in combination with Coumaphos.
Trospium The therapeutic efficacy of Trospium can be decreased when used in combination with Coumaphos.
Oxyphenonium The therapeutic efficacy of Oxyphenonium can be decreased when used in combination with Coumaphos.
Butabarbital The therapeutic efficacy of Butabarbital can be decreased when used in combination with Coumaphos.
Butalbital The therapeutic efficacy of Butalbital can be decreased when used in combination with Coumaphos.
Talbutal The therapeutic efficacy of Talbutal can be decreased when used in combination with Coumaphos.
Pentobarbital The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Coumaphos.
Ipratropium The therapeutic efficacy of Ipratropium can be decreased when used in combination with Coumaphos.
Metixene The therapeutic efficacy of Metixene can be decreased when used in combination with Coumaphos.
Trihexyphenidyl The therapeutic efficacy of Trihexyphenidyl can be decreased when used in combination with Coumaphos.
Oxyphencyclimine The therapeutic efficacy of Oxyphencyclimine can be decreased when used in combination with Coumaphos.
Procyclidine The therapeutic efficacy of Procyclidine can be decreased when used in combination with Coumaphos.
Profenamine The therapeutic efficacy of Profenamine can be decreased when used in combination with Coumaphos.
Secobarbital The therapeutic efficacy of Secobarbital can be decreased when used in combination with Coumaphos.
Methscopolamine bromide The therapeutic efficacy of Methscopolamine bromide can be decreased when used in combination with Coumaphos.
Metharbital The therapeutic efficacy of Metharbital can be decreased when used in combination with Coumaphos.
Darifenacin The therapeutic efficacy of Darifenacin can be decreased when used in combination with Coumaphos.
Tridihexethyl The therapeutic efficacy of Tridihexethyl can be decreased when used in combination with Coumaphos.
Triflupromazine The therapeutic efficacy of Triflupromazine can be decreased when used in combination with Coumaphos.
Dextromethorphan The therapeutic efficacy of Dextromethorphan can be decreased when used in combination with Coumaphos.
Anisotropine methylbromide The therapeutic efficacy of Anisotropine methylbromide can be decreased when used in combination with Coumaphos.
Thiopental The therapeutic efficacy of Thiopental can be decreased when used in combination with Coumaphos.
Mecamylamine The therapeutic efficacy of Mecamylamine can be decreased when used in combination with Coumaphos.
Pirenzepine The therapeutic efficacy of Pirenzepine can be decreased when used in combination with Coumaphos.
Paroxetine The therapeutic efficacy of Paroxetine can be decreased when used in combination with Coumaphos.
Homatropine methylbromide The therapeutic efficacy of Homatropine methylbromide can be decreased when used in combination with Coumaphos.
Scopolamine The therapeutic efficacy of Scopolamine can be decreased when used in combination with Coumaphos.
Benzquinamide The therapeutic efficacy of Benzquinamide can be decreased when used in combination with Coumaphos.
Clidinium The therapeutic efficacy of Clidinium can be decreased when used in combination with Coumaphos.
Propiomazine The therapeutic efficacy of Propiomazine can be decreased when used in combination with Coumaphos.
Propantheline The therapeutic efficacy of Propantheline can be decreased when used in combination with Coumaphos.
Primidone The therapeutic efficacy of Primidone can be decreased when used in combination with Coumaphos.
Dicyclomine The therapeutic efficacy of Dicyclomine can be decreased when used in combination with Coumaphos.
Biperiden The therapeutic efficacy of Biperiden can be decreased when used in combination with Coumaphos.
Methylphenobarbital The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Coumaphos.
Methantheline The therapeutic efficacy of Methantheline can be decreased when used in combination with Coumaphos.
Hexafluronium The therapeutic efficacy of Hexafluronium can be decreased when used in combination with Coumaphos.
Cycrimine The therapeutic efficacy of Cycrimine can be decreased when used in combination with Coumaphos.
Glycopyrronium The therapeutic efficacy of Glycopyrronium can be decreased when used in combination with Coumaphos.
Oxybutynin The therapeutic efficacy of Oxybutynin can be decreased when used in combination with Coumaphos.
Pentolinium The therapeutic efficacy of Pentolinium can be decreased when used in combination with Coumaphos.
Flavoxate The therapeutic efficacy of Flavoxate can be decreased when used in combination with Coumaphos.
Phenobarbital The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Coumaphos.
Diphenidol The therapeutic efficacy of Diphenidol can be decreased when used in combination with Coumaphos.
Fenoterol The therapeutic efficacy of Fenoterol can be decreased when used in combination with Coumaphos.
Amobarbital The therapeutic efficacy of Amobarbital can be decreased when used in combination with Coumaphos.
Aprobarbital The therapeutic efficacy of Aprobarbital can be decreased when used in combination with Coumaphos.
Butobarbital The therapeutic efficacy of Butobarbital can be decreased when used in combination with Coumaphos.
Heptabarbital The therapeutic efficacy of Heptabarbital can be decreased when used in combination with Coumaphos.
Hexobarbital The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Coumaphos.
Tiotropium The therapeutic efficacy of Tiotropium can be decreased when used in combination with Coumaphos.
Barbital The therapeutic efficacy of Barbital can be decreased when used in combination with Coumaphos.
Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione The therapeutic efficacy of Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione can be decreased when used in combination with Coumaphos.
Isopropamide The therapeutic efficacy of Isopropamide can be decreased when used in combination with Coumaphos.
Mepenzolate The therapeutic efficacy of Mepenzolate can be decreased when used in combination with Coumaphos.
Gantacurium The therapeutic efficacy of Gantacurium can be decreased when used in combination with Coumaphos.
Pizotifen The therapeutic efficacy of Pizotifen can be decreased when used in combination with Coumaphos.
Fesoterodine The therapeutic efficacy of Fesoterodine can be decreased when used in combination with Coumaphos.
Hexocyclium The therapeutic efficacy of Hexocyclium can be decreased when used in combination with Coumaphos.
Dimetindene The therapeutic efficacy of Dimetindene can be decreased when used in combination with Coumaphos.
Agmatine The therapeutic efficacy of Agmatine can be decreased when used in combination with Coumaphos.
Hexamethonium The therapeutic efficacy of Hexamethonium can be decreased when used in combination with Coumaphos.
Dexetimide The therapeutic efficacy of Dexetimide can be decreased when used in combination with Coumaphos.
Benactyzine The therapeutic efficacy of Benactyzine can be decreased when used in combination with Coumaphos.
Umeclidinium The therapeutic efficacy of Umeclidinium can be decreased when used in combination with Coumaphos.
Imidafenacin The therapeutic efficacy of Imidafenacin can be decreased when used in combination with Coumaphos.
Butylscopolamine The therapeutic efficacy of Butylscopolamine can be decreased when used in combination with Coumaphos.
Thonzylamine The therapeutic efficacy of Thonzylamine can be decreased when used in combination with Coumaphos.
Methscopolamine The therapeutic efficacy of Methscopolamine can be decreased when used in combination with Coumaphos.
Revefenacin The therapeutic efficacy of Revefenacin can be decreased when used in combination with Coumaphos.
Oxitropium The therapeutic efficacy of Oxitropium can be decreased when used in combination with Coumaphos.
Propiverine The therapeutic efficacy of Propiverine can be decreased when used in combination with Coumaphos.
Batefenterol The therapeutic efficacy of Batefenterol can be decreased when used in combination with Coumaphos.
Mebeverine The therapeutic efficacy of Mebeverine can be decreased when used in combination with Coumaphos.
Tropatepine The therapeutic efficacy of Tropatepine can be decreased when used in combination with Coumaphos.
Prifinium The therapeutic efficacy of Prifinium can be decreased when used in combination with Coumaphos.
Piperidolate The therapeutic efficacy of Piperidolate can be decreased when used in combination with Coumaphos.
Benzilone The therapeutic efficacy of Benzilone can be decreased when used in combination with Coumaphos.
Difemerine The therapeutic efficacy of Difemerine can be decreased when used in combination with Coumaphos.
Phenglutarimide The therapeutic efficacy of Phenglutarimide can be decreased when used in combination with Coumaphos.
Mazaticol The therapeutic efficacy of Mazaticol can be decreased when used in combination with Coumaphos.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 8523496
    Fang TC, Chen KW, Wu MH, Sung JM, Huang JJ: Coumaphos intoxications mimic food poisoning. J Toxicol Clin Toxicol. 1995;33(6):699-703.
  • PMID: 10808995
    Jindal T, Singh DK, Agarwal HC: Persistence, degradation and leaching of coumaphos in soil. J Environ Sci Health B. 2000 May;35(3):309-20.
  • PMID: 11990357
    Jindal T, Singh DK, Agarwal HC: Persistence and degradation of coumaphos in model cattle dipping vats. J Environ Sci Health B. 2002 Jan;37(1):33-42.
  • PMID: 5680751
    Janes MJ, Hayes BW, Beardsley DW: Horn fly control with coumaphos. J Econ Entomol. 1968 Oct;61(5):1176-8.
  • PMID: 14215377
    FAULKNER LC, CARROLL EJ, BENJAMIN M: EFFECT OF COUMAPHOS ON BULLS. J Am Vet Med Assoc. 1964 Sep 1;145:456-9.
  • PMID: 16538949
    Enzo O: Acute poisoning from food contaminated by coumaphos. Wilderness Environ Med. 2006 Spring;17(1):67-9.
  • PMID: 12806395
    Authors unspecified: Bioassay of coumaphos for possible carcinogenicity. Natl Cancer Inst Carcinog Tech Rep Ser. 1979;96:1-203.
  • PMID: 5950512
    Strickland RK, Gerrish RR: Efficacy of coumaphos against Psoroptes ovis. J Am Vet Med Assoc. 1966 Mar 1;148(5):553-5.
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