Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis of monoamine oxidases and prostaglandins. All the abovementioned effects are translated into the overexcitation, paralysis, and death in insects.
Amitraz presents a lower effect in mammals and thus, it is widely used in the treatment of mite- or tick-infestation of dogs.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Amitraz may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Amitraz may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Amitraz may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Amitraz may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Amitraz may decrease the antihypertensive activities of Torasemide. |
| Isradipine | Amitraz may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Amitraz may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Amitraz may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Amitraz may decrease the antihypertensive activities of Nitroprusside. |
| Diltiazem | Amitraz may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Amitraz may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Amitraz may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Amitraz may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Amitraz may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Amitraz may decrease the antihypertensive activities of Nisoldipine. |
| Bendroflumethiazide | Amitraz may decrease the antihypertensive activities of Bendroflumethiazide. |
| Fosinopril | Amitraz may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Amitraz may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Amitraz may decrease the antihypertensive activities of Metolazone. |
| Lercanidipine | Amitraz may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Amitraz may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Amitraz may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Amitraz may decrease the antihypertensive activities of Enalapril. |
| Cyclothiazide | Amitraz may decrease the antihypertensive activities of Cyclothiazide. |
| Candoxatril | Amitraz may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Amitraz may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Amitraz may decrease the antihypertensive activities of Losartan. |
| Moexipril | Amitraz may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Amitraz may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Amitraz may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Amitraz may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Amitraz may decrease the antihypertensive activities of Metyrosine. |
| Hydroflumethiazide | Amitraz may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Amitraz may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Amitraz may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Amitraz may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Amitraz may decrease the antihypertensive activities of Fenoldopam. |
| Indapamide | Amitraz may decrease the antihypertensive activities of Indapamide. |
| Tadalafil | Amitraz may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Amitraz may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Amitraz may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Amitraz may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Amitraz may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Amitraz may decrease the antihypertensive activities of Methyldopa. |
| Hydrochlorothiazide | Amitraz may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Amitraz may decrease the antihypertensive activities of Trichlormethiazide. |
| Irbesartan | Amitraz may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Amitraz may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Amitraz may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Amitraz may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Amitraz may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Amitraz may decrease the antihypertensive activities of Diazoxide. |
| Captopril | Amitraz may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Amitraz may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Amitraz may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Amitraz may decrease the antihypertensive activities of Hydralazine. |
| Polythiazide | Amitraz may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Amitraz may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Amitraz may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Amitraz may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Amitraz may decrease the antihypertensive activities of Mibefradil. |
| Tienilic acid | Amitraz may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Amitraz may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Amitraz may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Amitraz may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Amitraz may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Amitraz may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Amitraz may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Amitraz may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Amitraz may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Amitraz may decrease the antihypertensive activities of Macitentan. |
| Hexamethonium | Amitraz may decrease the antihypertensive activities of Hexamethonium. |
| Aliskiren | Amitraz may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Amitraz may decrease the antihypertensive activities of Nicorandil. |
| Efonidipine | Amitraz may decrease the antihypertensive activities of Efonidipine. |
| Lacidipine | Amitraz may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Amitraz may decrease the antihypertensive activities of Manidipine. |
| Rauwolfia serpentina root | Amitraz may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Amitraz may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Amitraz may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Amitraz may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Amitraz may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Amitraz may decrease the antihypertensive activities of BQ-123. |
| Tetrahydropalmatine | Amitraz may decrease the antihypertensive activities of Tetrahydropalmatine. |
| Cicletanine | Amitraz may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Amitraz may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Amitraz may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Amitraz may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Amitraz may decrease the antihypertensive activities of Delapril. |
| Vincamine | Amitraz may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Amitraz may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Amitraz may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Amitraz may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Amitraz may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Amitraz may decrease the antihypertensive activities of Cadralazine. |
| Cyclopenthiazide | Amitraz may decrease the antihypertensive activities of Cyclopenthiazide. |
| Bietaserpine | Amitraz may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Amitraz may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Amitraz may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Amitraz may decrease the antihypertensive activities of Guanoclor. |