Pidotimod

DB11364

small molecule experimental

Deskripsi

Pidotimod is a synthetic dipeptide with immunomodulatory properties.A7956

Struktur Molekul 2D

Berat 244.27
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Half life of 4 h [L929].
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Bioavailability of 45% L929.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

95% of intravenous dose is eliminated in the urine as the parent compound L929.

Interaksi Obat

727 Data
Cyclosporine Cyclosporine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Icosapent Icosapent may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefotiam Cefotiam may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Mesalazine Mesalazine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefmenoxime Cefmenoxime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefmetazole Cefmetazole may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Pamidronic acid Pamidronic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Tenofovir disoproxil Tenofovir disoproxil may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Indomethacin Indomethacin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cidofovir Cidofovir may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefpiramide Cefpiramide may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftazidime Ceftazidime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Loracarbef Loracarbef may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefalotin Cefalotin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Nabumetone Nabumetone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ketorolac Ketorolac may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Tenoxicam Tenoxicam may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Celecoxib Celecoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefotaxime Cefotaxime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Tolmetin Tolmetin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Foscarnet Foscarnet may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Rofecoxib Rofecoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Piroxicam Piroxicam may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Methotrexate Methotrexate may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cephalexin Cephalexin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Fenoprofen Fenoprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Valaciclovir Valaciclovir may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Valdecoxib Valdecoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Diclofenac Diclofenac may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Sulindac Sulindac may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Bacitracin Bacitracin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Amphotericin B Amphotericin B may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cephaloglycin Cephaloglycin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Flurbiprofen Flurbiprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Adefovir dipivoxil Adefovir dipivoxil may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Pentamidine Pentamidine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Etodolac Etodolac may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Mefenamic acid Mefenamic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Acyclovir Acyclovir may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Naproxen Naproxen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Sulfasalazine Sulfasalazine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Phenylbutazone Phenylbutazone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Meloxicam Meloxicam may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Carprofen Carprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefaclor Cefaclor may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Diflunisal Diflunisal may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Tacrolimus Tacrolimus may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceforanide Ceforanide may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Salicylic acid Salicylic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Meclofenamic acid Meclofenamic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Acetylsalicylic acid Acetylsalicylic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Carboplatin Carboplatin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Oxaprozin Oxaprozin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ketoprofen Ketoprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Balsalazide Balsalazide may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ibuprofen Ibuprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefditoren Cefditoren may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Atazanavir Atazanavir may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Colistimethate Colistimethate may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefuroxime Cefuroxime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefapirin Cefapirin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefadroxil Cefadroxil may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefprozil Cefprozil may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftriaxone Ceftriaxone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Olsalazine Olsalazine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Lumiracoxib Lumiracoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefamandole Cefamandole may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefazolin Cefazolin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefonicid Cefonicid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefoperazone Cefoperazone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefotetan Cefotetan may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefoxitin Cefoxitin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftizoxime Ceftizoxime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefradine Cefradine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Magnesium salicylate Magnesium salicylate may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Salsalate Salsalate may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Choline magnesium trisalicylate Choline magnesium trisalicylate may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefepime Cefepime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefacetrile Cefacetrile may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftibuten Ceftibuten may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cefpodoxime Cefpodoxime may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Antrafenine Antrafenine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Aminophenazone Aminophenazone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Antipyrine Antipyrine may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Tiaprofenic acid Tiaprofenic acid may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Lopinavir Lopinavir may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Etoricoxib Etoricoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Hydrolyzed Cephalothin Hydrolyzed Cephalothin may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cephalothin Group Cephalothin Group may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Oxyphenbutazone Oxyphenbutazone may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Latamoxef Latamoxef may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Nimesulide Nimesulide may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Benoxaprofen Benoxaprofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Metamizole Metamizole may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Zomepirac Zomepirac may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftobiprole Ceftobiprole may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Cimicoxib Cimicoxib may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Ceftaroline fosamil Ceftaroline fosamil may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Lornoxicam Lornoxicam may decrease the excretion rate of Pidotimod which could result in a higher serum level.
Aceclofenac Aceclofenac may decrease the excretion rate of Pidotimod which could result in a higher serum level.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 25999796
    Ferrario BE, Garuti S, Braido F, Canonica GW: Pidotimod: the state of art. Clin Mol Allergy. 2015 May 21;13(1):8. doi: 10.1186/s12948-015-0012-1. eCollection 2015.
  • PMID: 23663325
    Carta S, Silvestri M, Rossi GA: Modulation of airway epithelial cell functions by Pidotimod: NF-kB cytoplasmatic expression and its nuclear translocation are associated with an increased TLR-2 expression. Ital J Pediatr. 2013 May 10;39:29. doi: 10.1186/1824-7288-39-29.
  • PMID: 12946237
    Kidd P: Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease. Altern Med Rev. 2003 Aug;8(3):223-46.
  • PMID: 19712757
    Giagulli C, Noerder M, Avolio M, Becker PD, Fiorentini S, Guzman CA, Caruso A: Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol. 2009 Nov;9(12):1366-73. doi: 10.1016/j.intimp.2009.08.010. Epub 2009 Aug 25.

Contoh Produk & Brand

Produk: 0 • International brands: 1
International Brands
  • Pilimod

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