Ascorbyl phosphate

DB11352

small molecule approved

Deskripsi

Ascorbyl phosphate is a synthetic form of Vitamin C and is found in different salt forms such as magnesium ascorbyl phosphate and sodium ascorbyl phosphate. These salts are present in cosmetic products at concentrations ranging from 0.001 % to 3% A27211. As vitamin C is susceptible to breakdown of compound and discoloration in cosmetic formulations, ascorbyl phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin C that is readily absorbed into the skin with a hydrating effect on the skin A27212. While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate an antioxidant action to act as a free radical scavenger and increases collagen production *in vitro* A27212.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

5 Data
Erythromycin The therapeutic efficacy of Erythromycin can be decreased when used in combination with Ascorbyl phosphate.
Kanamycin The therapeutic efficacy of Kanamycin can be decreased when used in combination with Ascorbyl phosphate.
Streptomycin The therapeutic efficacy of Streptomycin can be decreased when used in combination with Ascorbyl phosphate.
Doxycycline The therapeutic efficacy of Doxycycline can be decreased when used in combination with Ascorbyl phosphate.
Lincomycin The therapeutic efficacy of Lincomycin can be decreased when used in combination with Ascorbyl phosphate.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 18492184
    Klock J, Ikeno H, Ohmori K, Nishikawa T, Vollhardt J, Schehlmann V: Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris. Int J Cosmet Sci. 2005 Jun;27(3):171-6. doi: 10.1111/j.1467-2494.2005.00263.x.
  • PMID: 23741676
    Telang PS: Vitamin C in dermatology. Indian Dermatol Online J. 2013 Apr;4(2):143-6. doi: 10.4103/2229-5178.110593.

Contoh Produk & Brand

Produk: 4 • International brands: 0
Produk
  • ELCURE C Serum
    Liquid • 500 mg/50mL • Topical • US • OTC
  • ELCURE Vitamin C Serum
    Liquid • 1.5 g/50mL • Topical • US • OTC
  • K Oxiderm OP Post Procedure skin care bruise
    Cream • 0.5 g/100mL • Topical • US • OTC
  • Le-Blen Vitamin C Serum
    Lotion • - • Topical • US • OTC

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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