Calcium Phosphate

DB11348

small molecule approved

Deskripsi

Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes FDA Label L851.

Struktur Molekul 2D

Berat 310.177
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

212 Data
Deferiprone The serum concentration of Deferiprone can be decreased when it is combined with Calcium Phosphate.
Dobutamine The therapeutic efficacy of Dobutamine can be decreased when used in combination with Calcium Phosphate.
Dolutegravir The serum concentration of Dolutegravir can be decreased when it is combined with Calcium Phosphate.
Eltrombopag The serum concentration of Eltrombopag can be decreased when it is combined with Calcium Phosphate.
Estramustine Calcium Phosphate can cause a decrease in the absorption of Estramustine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcium acetate The risk or severity of adverse effects can be increased when Calcium Phosphate is combined with Calcium acetate.
Acetyldigitoxin Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Acetyldigitoxin.
Deslanoside Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Deslanoside.
Ouabain Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Ouabain.
Digitoxin Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Digitoxin.
Oleandrin Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Oleandrin.
Cymarin Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Cymarin.
Proscillaridin Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Proscillaridin.
Lanatoside C Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Lanatoside C.
Gitoformate Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Gitoformate.
Peruvoside Calcium Phosphate may increase the arrhythmogenic and cardiotoxic activities of Peruvoside.
Grepafloxacin Calcium Phosphate can cause a decrease in the absorption of Grepafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Enoxacin Calcium Phosphate can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pefloxacin Calcium Phosphate can cause a decrease in the absorption of Pefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ciprofloxacin Calcium Phosphate can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Trovafloxacin Calcium Phosphate can cause a decrease in the absorption of Trovafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nalidixic acid Calcium Phosphate can cause a decrease in the absorption of Nalidixic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rosoxacin Calcium Phosphate can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cinoxacin Calcium Phosphate can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lomefloxacin Calcium Phosphate can cause a decrease in the absorption of Lomefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Gatifloxacin Calcium Phosphate can cause a decrease in the absorption of Gatifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Norfloxacin Calcium Phosphate can cause a decrease in the absorption of Norfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Gemifloxacin Calcium Phosphate can cause a decrease in the absorption of Gemifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ofloxacin Calcium Phosphate can cause a decrease in the absorption of Ofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sparfloxacin Calcium Phosphate can cause a decrease in the absorption of Sparfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Temafloxacin Calcium Phosphate can cause a decrease in the absorption of Temafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fleroxacin Calcium Phosphate can cause a decrease in the absorption of Fleroxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Technetium Tc-99m ciprofloxacin Calcium Phosphate can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Garenoxacin Calcium Phosphate can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nemonoxacin Calcium Phosphate can cause a decrease in the absorption of Nemonoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Flumequine Calcium Phosphate can cause a decrease in the absorption of Flumequine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Enrofloxacin Calcium Phosphate can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Orbifloxacin Calcium Phosphate can cause a decrease in the absorption of Orbifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sarafloxacin Calcium Phosphate can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Difloxacin Calcium Phosphate can cause a decrease in the absorption of Difloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pazufloxacin Calcium Phosphate can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Prulifloxacin Calcium Phosphate can cause a decrease in the absorption of Prulifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Delafloxacin Calcium Phosphate can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sitafloxacin Calcium Phosphate can cause a decrease in the absorption of Sitafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxolinic acid Calcium Phosphate can cause a decrease in the absorption of Oxolinic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rufloxacin Calcium Phosphate can cause a decrease in the absorption of Rufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pipemidic acid Calcium Phosphate can cause a decrease in the absorption of Pipemidic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Strontium ranelate The serum concentration of Strontium ranelate can be decreased when it is combined with Calcium Phosphate.
Doxycycline The serum concentration of Doxycycline can be decreased when it is combined with Calcium Phosphate.
Lymecycline The serum concentration of Lymecycline can be decreased when it is combined with Calcium Phosphate.
Clomocycline The serum concentration of Clomocycline can be decreased when it is combined with Calcium Phosphate.
Oxytetracycline The serum concentration of Oxytetracycline can be decreased when it is combined with Calcium Phosphate.
Demeclocycline The serum concentration of Demeclocycline can be decreased when it is combined with Calcium Phosphate.
Tetracycline The serum concentration of Tetracycline can be decreased when it is combined with Calcium Phosphate.
Metacycline The serum concentration of Metacycline can be decreased when it is combined with Calcium Phosphate.
Minocycline The serum concentration of Minocycline can be decreased when it is combined with Calcium Phosphate.
Sarecycline The serum concentration of Sarecycline can be decreased when it is combined with Calcium Phosphate.
Omadacycline The serum concentration of Omadacycline can be decreased when it is combined with Calcium Phosphate.
Penimepicycline The serum concentration of Penimepicycline can be decreased when it is combined with Calcium Phosphate.
Methyclothiazide Methyclothiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Chlorthalidone Chlorthalidone may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Bendroflumethiazide Bendroflumethiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Metolazone Metolazone may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Benzthiazide Benzthiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Hydroflumethiazide Hydroflumethiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Indapamide Indapamide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Chlorothiazide Chlorothiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Hydrochlorothiazide Hydrochlorothiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Trichlormethiazide Trichlormethiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Polythiazide Polythiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Quinethazone Quinethazone may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Cyclopenthiazide Cyclopenthiazide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Epitizide Epitizide may decrease the excretion rate of Calcium Phosphate which could result in a higher serum level.
Triethylenetetramine Calcium Phosphate can cause a decrease in the absorption of Triethylenetetramine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Calcitriol The risk or severity of adverse effects can be increased when Calcitriol is combined with Calcium Phosphate.
Calcifediol The risk or severity of adverse effects can be increased when Calcifediol is combined with Calcium Phosphate.
Paricalcitol The risk or severity of adverse effects can be increased when Paricalcitol is combined with Calcium Phosphate.
Dihydrotachysterol The risk or severity of adverse effects can be increased when Dihydrotachysterol is combined with Calcium Phosphate.
Alfacalcidol The risk or severity of adverse effects can be increased when Alfacalcidol is combined with Calcium Phosphate.
Calcipotriol The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium Phosphate.
Seocalcitol The risk or severity of adverse effects can be increased when Seocalcitol is combined with Calcium Phosphate.
Inecalcitol The risk or severity of adverse effects can be increased when Inecalcitol is combined with Calcium Phosphate.
Becocalcidiol The risk or severity of adverse effects can be increased when Becocalcidiol is combined with Calcium Phosphate.
Eldecalcitol The risk or severity of adverse effects can be increased when Eldecalcitol is combined with Calcium Phosphate.
1alpha,24S-Dihydroxyvitamin D2 The risk or severity of adverse effects can be increased when 1alpha,24S-Dihydroxyvitamin D2 is combined with Calcium Phosphate.
Elocalcitol The risk or severity of adverse effects can be increased when Elocalcitol is combined with Calcium Phosphate.
Maxacalcitol The risk or severity of adverse effects can be increased when Maxacalcitol is combined with Calcium Phosphate.
Doxercalciferol The risk or severity of adverse effects can be increased when Doxercalciferol is combined with Calcium Phosphate.
1alpha-Hydroxyvitamin D5 The risk or severity of adverse effects can be increased when 1alpha-Hydroxyvitamin D5 is combined with Calcium Phosphate.
Tacalcitol The risk or severity of adverse effects can be increased when Tacalcitol is combined with Calcium Phosphate.
Previtamin D(3) The risk or severity of adverse effects can be increased when Previtamin D(3) is combined with Calcium Phosphate.
Thyrotropin alfa The therapeutic efficacy of Thyrotropin alfa can be decreased when used in combination with Calcium Phosphate.
Liothyronine The therapeutic efficacy of Liothyronine can be decreased when used in combination with Calcium Phosphate.
Levothyroxine The therapeutic efficacy of Levothyroxine can be decreased when used in combination with Calcium Phosphate.
Liotrix The therapeutic efficacy of Liotrix can be decreased when used in combination with Calcium Phosphate.
Tiratricol The therapeutic efficacy of Tiratricol can be decreased when used in combination with Calcium Phosphate.
Thyroid, porcine The therapeutic efficacy of Thyroid, porcine can be decreased when used in combination with Calcium Phosphate.
Pamidronic acid The serum concentration of Pamidronic acid can be decreased when it is combined with Calcium Phosphate.
Zoledronic acid The serum concentration of Zoledronic acid can be decreased when it is combined with Calcium Phosphate.
Alendronic acid The serum concentration of Alendronic acid can be decreased when it is combined with Calcium Phosphate.

Target Protein

Extracellular calcium-sensing receptor CASR
Calreticulin CALR
Calcium and integrin-binding protein 1 CIB1
Programmed cell death protein 6 PDCD6
Sorcin SRI
Calcineurin B homologous protein 1 CHP1
SPARC SPARC
Calnexin CANX
Fibrillin-2 FBN2
Protein S100-B S100B
Calsequestrin-2 CASQ2
Regucalcin RGN
Peflin PEF1
Protein S100-A6 S100A6
Translationally-controlled tumor protein TPT1
Calcium and integrin-binding family member 2 CIB2
Protein S100-A13 S100A13
Calsequestrin-1 CASQ1
Nucleobindin-1 NUCB1
Nucleobindin-2 NUCB2
Fibrillin-3 FBN3
Grancalcin GCA
Calcium-dependent secretion activator 1 CADPS
Calmodulin-2 CALM2
Calmodulin-3 CALM3
Protein S100-A16 S100A16
Calretinin CALB2
Calcyphosin CAPS
Calcium-dependent secretion activator 2 CADPS2
Calreticulin-3 CALR3
Neurexin-1 NRXN1
Neuronal calcium sensor 1 NCS1
Calmodulin CALM1

Referensi & Sumber

Artikel (PubMed)
  • PMID: 18782374
    Reynolds EC: Calcium phosphate-based remineralization systems: scientific evidence? Aust Dent J. 2008 Sep;53(3):268-73. doi: 10.1111/j.1834-7819.2008.00061.x.
Textbook
  • ISBN: 978-0-07-17803-2
    Barrett KE, Barman SM, Boitano S, Brooks HL (2012). Ganong's Review of Medical Physiology (24th ed.). McGraw Hill.

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