Dihydroergocornine effect on fertility was tested in preclinical studies. The reported effect was a decreased weight gain in neonates.T194 Overdosing has also been reported to present effects of fall of blood pressure and a decrease in heart rate to 13 beats per minute.A32968 To know more about the pharmacokinetics please visit DB01049.
Dihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects.A32962 It is an artificial derivative of the crude extract of ergot and later purified, ergocornine.A32964 The formation of dihydroergocornine implies the hydrogenation of the double bonds in the lysergic acid.A32965 Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl)-ergotaman-3',6',18-trione.T190 It is found as one of the components in the ergoloid mesylate mixture. To know more about this mixture please refer to DB01049
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Phenytoin | The metabolism of Dihydroergocornine can be increased when combined with Phenytoin. |
| Fosphenytoin | The metabolism of Dihydroergocornine can be increased when combined with Fosphenytoin. |
| Valsartan | Dihydroergocornine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Dihydroergocornine may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Dihydroergocornine may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Dihydroergocornine may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Dihydroergocornine may decrease the antihypertensive activities of Torasemide. |
| Guanadrel | Dihydroergocornine may decrease the antihypertensive activities of Guanadrel. |
| Olmesartan | Dihydroergocornine may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Dihydroergocornine may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Dihydroergocornine may decrease the antihypertensive activities of Nitroprusside. |
| Minoxidil | Dihydroergocornine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Dihydroergocornine may decrease the antihypertensive activities of Treprostinil. |
| Bendroflumethiazide | Dihydroergocornine may decrease the antihypertensive activities of Bendroflumethiazide. |
| Prazosin | Dihydroergocornine may decrease the antihypertensive activities of Prazosin. |
| Fosinopril | Dihydroergocornine may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Dihydroergocornine may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Dihydroergocornine may decrease the antihypertensive activities of Metolazone. |
| Benazepril | Dihydroergocornine may decrease the antihypertensive activities of Benazepril. |
| Cyclothiazide | Dihydroergocornine may decrease the antihypertensive activities of Cyclothiazide. |
| Candoxatril | Dihydroergocornine may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Dihydroergocornine may decrease the antihypertensive activities of Mecamylamine. |
| Moexipril | Dihydroergocornine may decrease the antihypertensive activities of Moexipril. |
| Lisinopril | Dihydroergocornine may decrease the antihypertensive activities of Lisinopril. |
| Metyrosine | Dihydroergocornine may decrease the antihypertensive activities of Metyrosine. |
| Hydroflumethiazide | Dihydroergocornine may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Dihydroergocornine may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Dihydroergocornine may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Dihydroergocornine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Eprosartan | Dihydroergocornine may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Dihydroergocornine may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Dihydroergocornine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Dihydroergocornine may decrease the antihypertensive activities of Telmisartan. |
| Hydrochlorothiazide | Dihydroergocornine may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Dihydroergocornine may decrease the antihypertensive activities of Trichlormethiazide. |
| Deserpidine | Dihydroergocornine may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Dihydroergocornine may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Dihydroergocornine may decrease the antihypertensive activities of Trimethaphan. |
| Diazoxide | Dihydroergocornine may decrease the antihypertensive activities of Diazoxide. |
| Bretylium | Dihydroergocornine may decrease the antihypertensive activities of Bretylium. |
| Terazosin | Dihydroergocornine may decrease the antihypertensive activities of Terazosin. |
| Captopril | Dihydroergocornine may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Dihydroergocornine may decrease the antihypertensive activities of Epoprostenol. |
| Polythiazide | Dihydroergocornine may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Dihydroergocornine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Dihydroergocornine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Dihydroergocornine may decrease the antihypertensive activities of Spirapril. |
| Tienilic acid | Dihydroergocornine may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Dihydroergocornine may decrease the antihypertensive activities of Debrisoquine. |
| Diethylnorspermine | Dihydroergocornine may decrease the antihypertensive activities of Diethylnorspermine. |
| Temocapril | Dihydroergocornine may decrease the antihypertensive activities of Temocapril. |
| Hexamethonium | Dihydroergocornine may decrease the antihypertensive activities of Hexamethonium. |
| Trimazosin | Dihydroergocornine may decrease the antihypertensive activities of Trimazosin. |
| Nicorandil | Dihydroergocornine may decrease the antihypertensive activities of Nicorandil. |
| Rauwolfia serpentina root | Dihydroergocornine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Dihydroergocornine may decrease the antihypertensive activities of Enalaprilat. |
| Angiotensin 1-7 | Dihydroergocornine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Dihydroergocornine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Dihydroergocornine may decrease the antihypertensive activities of BQ-123. |
| Cicletanine | Dihydroergocornine may decrease the antihypertensive activities of Cicletanine. |
| Dihydralazine | Dihydroergocornine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Dihydroergocornine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Dihydroergocornine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Dihydroergocornine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Dihydroergocornine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Dihydroergocornine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Dihydroergocornine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Dihydroergocornine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Dihydroergocornine may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Dihydroergocornine may decrease the antihypertensive activities of Cadralazine. |
| Cyclopenthiazide | Dihydroergocornine may decrease the antihypertensive activities of Cyclopenthiazide. |
| Bietaserpine | Dihydroergocornine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Dihydroergocornine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Dihydroergocornine may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Dihydroergocornine may decrease the antihypertensive activities of Guanoclor. |
| Muzolimine | Dihydroergocornine may decrease the antihypertensive activities of Muzolimine. |
| Xipamide | Dihydroergocornine may decrease the antihypertensive activities of Xipamide. |
| Candesartan | Dihydroergocornine may decrease the antihypertensive activities of Candesartan. |
| Tocopherylquinone | Dihydroergocornine may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Dihydroergocornine may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Dihydroergocornine may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Dihydroergocornine may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Dihydroergocornine may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Dihydroergocornine may decrease the antihypertensive activities of Quinaprilat. |
| Furosemide | Dihydroergocornine may decrease the antihypertensive activities of Furosemide. |
| Enalapril | Dihydroergocornine may decrease the antihypertensive activities of Enalapril. |
| Amlodipine | Dihydroergocornine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Dihydroergocornine may decrease the antihypertensive activities of Nimodipine. |
| Lercanidipine | Dihydroergocornine may decrease the antihypertensive activities of Lercanidipine. |
| Indapamide | Dihydroergocornine may decrease the antihypertensive activities of Indapamide. |
| Nitrendipine | Dihydroergocornine may decrease the antihypertensive activities of Nitrendipine. |
| Guanethidine | Dihydroergocornine may decrease the antihypertensive activities of Guanethidine. |
| Bepridil | Dihydroergocornine may decrease the antihypertensive activities of Bepridil. |
| Ambrisentan | Dihydroergocornine may decrease the antihypertensive activities of Ambrisentan. |
| Pinacidil | Dihydroergocornine may decrease the antihypertensive activities of Pinacidil. |
| Riociguat | Dihydroergocornine may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Dihydroergocornine may decrease the antihypertensive activities of Macitentan. |
| Aliskiren | Dihydroergocornine may decrease the antihypertensive activities of Aliskiren. |
| Lacidipine | Dihydroergocornine may decrease the antihypertensive activities of Lacidipine. |
| Niguldipine | Dihydroergocornine may decrease the antihypertensive activities of Niguldipine. |