Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza A27224. Protocatechualdehyde possesses antiproliferative and pro-apoptotic properties against human breast cancer cells and colorectal cancer cells by reducing the expression of pro-oncogenes ?-catenin and cyclin D1.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Collagenase clostridium histolyticum | The risk or severity of adverse effects can be increased when Protocatechualdehyde is combined with Collagenase clostridium histolyticum. |
| Apixaban | The risk or severity of adverse effects can be increased when Protocatechualdehyde is combined with Apixaban. |
| Calcium carbimide | The risk or severity of adverse effects can be increased when Calcium carbimide is combined with Protocatechualdehyde. |
| Disulfiram | The risk or severity of adverse effects can be increased when Disulfiram is combined with Protocatechualdehyde. |
| Bivalirudin | The risk or severity of bleeding can be increased when Bivalirudin is combined with Protocatechualdehyde. |
| Abciximab | The risk or severity of bleeding can be increased when Abciximab is combined with Protocatechualdehyde. |
| Dicoumarol | The risk or severity of bleeding can be increased when Dicoumarol is combined with Protocatechualdehyde. |
| Argatroban | The risk or severity of bleeding can be increased when Argatroban is combined with Protocatechualdehyde. |
| Ardeparin | The risk or severity of bleeding can be increased when Ardeparin is combined with Protocatechualdehyde. |
| Phenindione | The risk or severity of bleeding can be increased when Phenindione is combined with Protocatechualdehyde. |
| Fondaparinux | The risk or severity of bleeding can be increased when Fondaparinux is combined with Protocatechualdehyde. |
| Warfarin | The risk or severity of bleeding can be increased when Warfarin is combined with Protocatechualdehyde. |
| Pentosan polysulfate | The risk or severity of bleeding can be increased when Pentosan polysulfate is combined with Protocatechualdehyde. |
| Phenprocoumon | The risk or severity of bleeding can be increased when Phenprocoumon is combined with Protocatechualdehyde. |
| Edetic acid | The risk or severity of bleeding can be increased when Edetic acid is combined with Protocatechualdehyde. |
| Heparin | The risk or severity of bleeding can be increased when Heparin is combined with Protocatechualdehyde. |
| Enoxaparin | The risk or severity of bleeding can be increased when Enoxaparin is combined with Protocatechualdehyde. |
| Acenocoumarol | The risk or severity of bleeding can be increased when Acenocoumarol is combined with Protocatechualdehyde. |
| Ximelagatran | The risk or severity of bleeding can be increased when Ximelagatran is combined with Protocatechualdehyde. |
| Ancrod | The risk or severity of bleeding can be increased when Ancrod is combined with Protocatechualdehyde. |
| Rivaroxaban | The risk or severity of bleeding can be increased when Rivaroxaban is combined with Protocatechualdehyde. |
| Sulodexide | The risk or severity of bleeding can be increased when Sulodexide is combined with Protocatechualdehyde. |
| Idraparinux | The risk or severity of bleeding can be increased when Idraparinux is combined with Protocatechualdehyde. |
| Otamixaban | The risk or severity of bleeding can be increased when Otamixaban is combined with Protocatechualdehyde. |
| Dabigatran etexilate | The risk or severity of bleeding can be increased when Dabigatran etexilate is combined with Protocatechualdehyde. |
| Danaparoid | The risk or severity of bleeding can be increased when Danaparoid is combined with Protocatechualdehyde. |
| Dalteparin | The risk or severity of bleeding can be increased when Dalteparin is combined with Protocatechualdehyde. |
| Ethyl biscoumacetate | The risk or severity of bleeding can be increased when Ethyl biscoumacetate is combined with Protocatechualdehyde. |
| Nadroparin | The risk or severity of bleeding can be increased when Nadroparin is combined with Protocatechualdehyde. |
| Edoxaban | The risk or severity of bleeding can be increased when Edoxaban is combined with Protocatechualdehyde. |
| Dextran | The risk or severity of bleeding can be increased when Dextran is combined with Protocatechualdehyde. |
| Desirudin | The risk or severity of bleeding can be increased when Desirudin is combined with Protocatechualdehyde. |
| Protein C | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Protein C. |
| Antithrombin III human | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Antithrombin III human. |
| Letaxaban | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Letaxaban. |
| Darexaban | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Darexaban. |
| Nafamostat | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Nafamostat. |
| Gabexate | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Gabexate. |
| Troxerutin | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Troxerutin. |
| Fluindione | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Fluindione. |
| Protein S human | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Protein S human. |
| Melagatran | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Melagatran. |
| Sodium citrate | The risk or severity of bleeding can be increased when Sodium citrate is combined with Protocatechualdehyde. |
| Tenecteplase | The risk or severity of bleeding can be increased when Tenecteplase is combined with Protocatechualdehyde. |
| Drotrecogin alfa | The risk or severity of bleeding can be increased when Drotrecogin alfa is combined with Protocatechualdehyde. |
| Defibrotide | The risk or severity of bleeding can be increased when Defibrotide is combined with Protocatechualdehyde. |
| Tinzaparin | The risk or severity of bleeding can be increased when Tinzaparin is combined with Protocatechualdehyde. |
| Brinase | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Brinase. |
| Saruplase | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Saruplase. |
| Streptokinase | The risk or severity of bleeding can be increased when Streptokinase is combined with Protocatechualdehyde. |
| Desmoteplase | The risk or severity of bleeding can be increased when Desmoteplase is combined with Protocatechualdehyde. |
| Astaxanthin | The risk or severity of bleeding can be increased when Astaxanthin is combined with Protocatechualdehyde. |
| Urokinase | The risk or severity of bleeding can be increased when Urokinase is combined with Protocatechualdehyde. |
| Dipyridamole | The risk or severity of bleeding can be increased when Dipyridamole is combined with Protocatechualdehyde. |
| Epoprostenol | The risk or severity of bleeding can be increased when Epoprostenol is combined with Protocatechualdehyde. |
| Beraprost | The risk or severity of bleeding can be increased when Beraprost is combined with Protocatechualdehyde. |
| Prasugrel | The risk or severity of bleeding can be increased when Prasugrel is combined with Protocatechualdehyde. |
| Cangrelor | The risk or severity of bleeding can be increased when Cangrelor is combined with Protocatechualdehyde. |
| Triflusal | The risk or severity of bleeding can be increased when Triflusal is combined with Protocatechualdehyde. |
| Ticagrelor | The risk or severity of bleeding can be increased when Ticagrelor is combined with Protocatechualdehyde. |
| Ditazole | The risk or severity of bleeding can be increased when Ditazole is combined with Protocatechualdehyde. |
| Vorapaxar | The risk or severity of bleeding can be increased when Vorapaxar is combined with Protocatechualdehyde. |
| Bemiparin | The risk or severity of bleeding can be increased when Bemiparin is combined with Protocatechualdehyde. |
| Parnaparin | The risk or severity of bleeding can be increased when Parnaparin is combined with Protocatechualdehyde. |
| Clorindione | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Clorindione. |
| Diphenadione | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Diphenadione. |
| Tioclomarol | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Tioclomarol. |
| Lepirudin | The risk or severity of bleeding can be increased when Lepirudin is combined with Protocatechualdehyde. |
| Alteplase | The risk or severity of bleeding can be increased when Alteplase is combined with Protocatechualdehyde. |
| Reteplase | The risk or severity of bleeding can be increased when Reteplase is combined with Protocatechualdehyde. |
| Anistreplase | The risk or severity of bleeding can be increased when Anistreplase is combined with Protocatechualdehyde. |
| Tocopherylquinone | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Tocopherylquinone. |
| Amediplase | The risk or severity of bleeding can be increased when Amediplase is combined with Protocatechualdehyde. |
| 4-hydroxycoumarin | The risk or severity of bleeding can be increased when 4-hydroxycoumarin is combined with Protocatechualdehyde. |
| (R)-warfarin | The risk or severity of bleeding can be increased when (R)-warfarin is combined with Protocatechualdehyde. |
| (S)-Warfarin | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with (S)-Warfarin. |
| Betrixaban | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Betrixaban. |
| Antithrombin Alfa | The risk or severity of bleeding can be increased when Antithrombin Alfa is combined with Protocatechualdehyde. |
| Coumarin | The risk or severity of bleeding can be increased when Coumarin is combined with Protocatechualdehyde. |
| Dabigatran | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Dabigatran. |
| Semuloparin | The risk or severity of bleeding can be increased when Semuloparin is combined with Protocatechualdehyde. |
| Monteplase | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Monteplase. |
| Reviparin | The risk or severity of bleeding can be increased when Reviparin is combined with Protocatechualdehyde. |
| Dermatan sulfate | The risk or severity of bleeding can be increased when Protocatechualdehyde is combined with Dermatan sulfate. |
| SR-123781A | The risk or severity of bleeding can be increased when SR-123781A is combined with Protocatechualdehyde. |
| Trazodone | The risk or severity of bleeding can be increased when Trazodone is combined with Protocatechualdehyde. |
| Triamcinolone | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Triamcinolone. |
| Nintedanib | The risk or severity of bleeding can be increased when Nintedanib is combined with Protocatechualdehyde. |
| Escitalopram | The risk or severity of bleeding can be increased when Escitalopram is combined with Protocatechualdehyde. |
| Sertraline | The risk or severity of bleeding can be increased when Sertraline is combined with Protocatechualdehyde. |
| Methyclothiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Methyclothiazide. |
| Bendroflumethiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Bendroflumethiazide. |
| Benzthiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Benzthiazide. |
| Cyclothiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Cyclothiazide. |
| Hydroflumethiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Hydroflumethiazide. |
| Chlorothiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Chlorothiazide. |
| Hydrochlorothiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Hydrochlorothiazide. |
| Trichlormethiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Trichlormethiazide. |
| Polythiazide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Polythiazide. |
| Mebutizide | The therapeutic efficacy of Protocatechualdehyde can be decreased when used in combination with Mebutizide. |