Borage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as an herbal treatment of skin disorders including eczema, seborrheic dermatitis, and neurodermatitis as well as other inflammatory, cardiovascular and endocrine disorders, although its clinical efficacy and long-term effects are not fully elucidated yet. GLA, which accounts for approximately 24% of the oil, is converted to dihomo-?-linolenic acid (DGLA) which acts as a precursor to anti-inflammatory mediators such as 1-series prostaglandins and the 3-series leukotrienes. Borage oil may be found in foods or in skin care products.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Lorazepam | The therapeutic efficacy of Lorazepam can be decreased when used in combination with Borage oil. |
| Pregabalin | The therapeutic efficacy of Pregabalin can be decreased when used in combination with Borage oil. |
| Butalbital | The therapeutic efficacy of Butalbital can be decreased when used in combination with Borage oil. |
| Phenytoin | The therapeutic efficacy of Phenytoin can be decreased when used in combination with Borage oil. |
| Topiramate | The therapeutic efficacy of Topiramate can be decreased when used in combination with Borage oil. |
| Pentobarbital | The therapeutic efficacy of Pentobarbital can be decreased when used in combination with Borage oil. |
| Valproic acid | The therapeutic efficacy of Valproic acid can be decreased when used in combination with Borage oil. |
| Trimethadione | The therapeutic efficacy of Trimethadione can be decreased when used in combination with Borage oil. |
| Clobazam | The therapeutic efficacy of Clobazam can be decreased when used in combination with Borage oil. |
| Secobarbital | The therapeutic efficacy of Secobarbital can be decreased when used in combination with Borage oil. |
| Metharbital | The therapeutic efficacy of Metharbital can be decreased when used in combination with Borage oil. |
| Methohexital | The therapeutic efficacy of Methohexital can be decreased when used in combination with Borage oil. |
| Mephenytoin | The therapeutic efficacy of Mephenytoin can be decreased when used in combination with Borage oil. |
| Lamotrigine | The therapeutic efficacy of Lamotrigine can be decreased when used in combination with Borage oil. |
| Carbamazepine | The therapeutic efficacy of Carbamazepine can be decreased when used in combination with Borage oil. |
| Ethosuximide | The therapeutic efficacy of Ethosuximide can be decreased when used in combination with Borage oil. |
| Thiopental | The therapeutic efficacy of Thiopental can be decreased when used in combination with Borage oil. |
| Paramethadione | The therapeutic efficacy of Paramethadione can be decreased when used in combination with Borage oil. |
| Clorazepic acid | The therapeutic efficacy of Clorazepic acid can be decreased when used in combination with Borage oil. |
| Magnesium sulfate | The therapeutic efficacy of Magnesium sulfate can be decreased when used in combination with Borage oil. |
| Tizanidine | The therapeutic efficacy of Tizanidine can be decreased when used in combination with Borage oil. |
| Riluzole | The therapeutic efficacy of Riluzole can be decreased when used in combination with Borage oil. |
| Ethotoin | The therapeutic efficacy of Ethotoin can be decreased when used in combination with Borage oil. |
| Oxcarbazepine | The therapeutic efficacy of Oxcarbazepine can be decreased when used in combination with Borage oil. |
| Primidone | The therapeutic efficacy of Primidone can be decreased when used in combination with Borage oil. |
| Acetazolamide | The therapeutic efficacy of Acetazolamide can be decreased when used in combination with Borage oil. |
| Diazepam | The therapeutic efficacy of Diazepam can be decreased when used in combination with Borage oil. |
| Phensuximide | The therapeutic efficacy of Phensuximide can be decreased when used in combination with Borage oil. |
| Progabide | The therapeutic efficacy of Progabide can be decreased when used in combination with Borage oil. |
| Methylphenobarbital | The therapeutic efficacy of Methylphenobarbital can be decreased when used in combination with Borage oil. |
| Tiagabine | The therapeutic efficacy of Tiagabine can be decreased when used in combination with Borage oil. |
| Zonisamide | The therapeutic efficacy of Zonisamide can be decreased when used in combination with Borage oil. |
| Felbamate | The therapeutic efficacy of Felbamate can be decreased when used in combination with Borage oil. |
| Zaleplon | The therapeutic efficacy of Zaleplon can be decreased when used in combination with Borage oil. |
| Gabapentin | The therapeutic efficacy of Gabapentin can be decreased when used in combination with Borage oil. |
| Clonazepam | The therapeutic efficacy of Clonazepam can be decreased when used in combination with Borage oil. |
| Vigabatrin | The therapeutic efficacy of Vigabatrin can be decreased when used in combination with Borage oil. |
| Phenacemide | The therapeutic efficacy of Phenacemide can be decreased when used in combination with Borage oil. |
| Thiamylal | The therapeutic efficacy of Thiamylal can be decreased when used in combination with Borage oil. |
| Phenobarbital | The therapeutic efficacy of Phenobarbital can be decreased when used in combination with Borage oil. |
| Levetiracetam | The therapeutic efficacy of Levetiracetam can be decreased when used in combination with Borage oil. |
| Estazolam | The therapeutic efficacy of Estazolam can be decreased when used in combination with Borage oil. |
| Fosphenytoin | The therapeutic efficacy of Fosphenytoin can be decreased when used in combination with Borage oil. |
| Amobarbital | The therapeutic efficacy of Amobarbital can be decreased when used in combination with Borage oil. |
| Hexobarbital | The therapeutic efficacy of Hexobarbital can be decreased when used in combination with Borage oil. |
| Barbital | The therapeutic efficacy of Barbital can be decreased when used in combination with Borage oil. |
| Delorazepam | The therapeutic efficacy of Delorazepam can be decreased when used in combination with Borage oil. |
| Nitrazepam | The therapeutic efficacy of Nitrazepam can be decreased when used in combination with Borage oil. |
| 7-Nitroindazole | The therapeutic efficacy of 7-Nitroindazole can be decreased when used in combination with Borage oil. |
| Valpromide | The therapeutic efficacy of Valpromide can be decreased when used in combination with Borage oil. |
| Flunarizine | The therapeutic efficacy of Flunarizine can be decreased when used in combination with Borage oil. |
| Ezogabine | The therapeutic efficacy of Ezogabine can be decreased when used in combination with Borage oil. |
| Methsuximide | The therapeutic efficacy of Methsuximide can be decreased when used in combination with Borage oil. |
| Brivaracetam | The therapeutic efficacy of Brivaracetam can be decreased when used in combination with Borage oil. |
| Rufinamide | The therapeutic efficacy of Rufinamide can be decreased when used in combination with Borage oil. |
| Lacosamide | The therapeutic efficacy of Lacosamide can be decreased when used in combination with Borage oil. |
| Remacemide | The therapeutic efficacy of Remacemide can be decreased when used in combination with Borage oil. |
| Clomethiazole | The therapeutic efficacy of Clomethiazole can be decreased when used in combination with Borage oil. |
| Deramciclane | The therapeutic efficacy of Deramciclane can be decreased when used in combination with Borage oil. |
| Tramiprosate | The therapeutic efficacy of Tramiprosate can be decreased when used in combination with Borage oil. |
| Gaboxadol | The therapeutic efficacy of Gaboxadol can be decreased when used in combination with Borage oil. |
| Sulthiame | The therapeutic efficacy of Sulthiame can be decreased when used in combination with Borage oil. |
| Perampanel | The therapeutic efficacy of Perampanel can be decreased when used in combination with Borage oil. |
| Ifenprodil | The therapeutic efficacy of Ifenprodil can be decreased when used in combination with Borage oil. |
| Barbexaclone | The therapeutic efficacy of Barbexaclone can be decreased when used in combination with Borage oil. |
| Beclamide | The therapeutic efficacy of Beclamide can be decreased when used in combination with Borage oil. |
| Cannabidiol | The therapeutic efficacy of Cannabidiol can be decreased when used in combination with Borage oil. |
| Paraldehyde | The therapeutic efficacy of Paraldehyde can be decreased when used in combination with Borage oil. |
| Stiripentol | The therapeutic efficacy of Stiripentol can be decreased when used in combination with Borage oil. |
| Eslicarbazepine acetate | The therapeutic efficacy of Eslicarbazepine acetate can be decreased when used in combination with Borage oil. |
| Doramectin | The therapeutic efficacy of Doramectin can be decreased when used in combination with Borage oil. |
| Tiletamine | The therapeutic efficacy of Tiletamine can be decreased when used in combination with Borage oil. |
| Brexanolone | The therapeutic efficacy of Brexanolone can be decreased when used in combination with Borage oil. |
| Etiracetam | The therapeutic efficacy of Etiracetam can be decreased when used in combination with Borage oil. |
| Vinpocetine | The therapeutic efficacy of Vinpocetine can be decreased when used in combination with Borage oil. |
| Carisbamate | The therapeutic efficacy of Carisbamate can be decreased when used in combination with Borage oil. |
| Pheneturide | The therapeutic efficacy of Pheneturide can be decreased when used in combination with Borage oil. |
| Neocitrullamon | The therapeutic efficacy of Neocitrullamon can be decreased when used in combination with Borage oil. |
| Medazepam | The therapeutic efficacy of Medazepam can be decreased when used in combination with Borage oil. |
| Phenibut | The therapeutic efficacy of Phenibut can be decreased when used in combination with Borage oil. |
| Ethadione | The therapeutic efficacy of Ethadione can be decreased when used in combination with Borage oil. |
| Cannabidivarin | The therapeutic efficacy of Cannabidivarin can be decreased when used in combination with Borage oil. |
| Eslicarbazepine | The therapeutic efficacy of Eslicarbazepine can be decreased when used in combination with Borage oil. |
| JNJ-26489112 | The therapeutic efficacy of JNJ-26489112 can be decreased when used in combination with Borage oil. |
| Cenobamate | The therapeutic efficacy of Cenobamate can be decreased when used in combination with Borage oil. |
| Amifampridine | The risk or severity of seizure can be increased when Borage oil is combined with Amifampridine. |
| Dalfampridine | The risk or severity of seizure can be increased when Borage oil is combined with Dalfampridine. |
| Bupropion | The risk or severity of seizure can be increased when Bupropion is combined with Borage oil. |
| Fenfluramine | The therapeutic efficacy of Fenfluramine can be decreased when used in combination with Borage oil. |
| Ganaxolone | The therapeutic efficacy of Ganaxolone can be decreased when used in combination with Borage oil. |
| Hydroxychloroquine | The risk or severity of seizure can be increased when Hydroxychloroquine is combined with Borage oil. |