Peringatan Keamanan

Oral LD50 in rat is > 2000 mg/kg and dermal LD50 in rabbit is > 2000 mg/kg, respectively MSDS.

Bemotrizinol

DB11206

small molecule approved

Deskripsi

Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity A19212. It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application A19212, A32909. Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.

Struktur Molekul 2D

Berat 627.826
Wujud solid

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) No pharmacokinetic data available.
Volume Distribusi No pharmacokinetic data available.
Klirens (Clearance) No pharmacokinetic data available.

Absorpsi

No pharmacokinetic data available.

Metabolisme

No pharmacokinetic data available.

Rute Eliminasi

No pharmacokinetic data available.

Interaksi Obat

0 Data
Tidak ada data.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 11754532
    Ashby J, Tinwell H, Plautz J, Twomey K, Lefevre PA: Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S. Regul Toxicol Pharmacol. 2001 Dec;34(3):287-91. doi: 10.1006/rtph.2001.1511.
  • PMID: 23320122
    Latha MS, Martis J, Shobha V, Sham Shinde R, Bangera S, Krishnankutty B, Bellary S, Varughese S, Rao P, Naveen Kumar BR: Sunscreening agents: a review. J Clin Aesthet Dermatol. 2013 Jan;6(1):16-26.
  • PMID: 11594052
    Chatelain E, Gabard B: Photostabilization of butyl methoxydibenzoylmethane (Avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter. Photochem Photobiol. 2001 Sep;74(3):401-6.
  • PMID: 19002338
    Schleyer V, Weber O, Yazdi A, Benedix F, Dietz K, Rocken M, Berneburg M: Prevention of polymorphic light eruption with a sunscreen of very high protection level against UVB and UVA radiation under standardized photodiagnostic conditions. Acta Derm Venereol. 2008;88(6):555-60. doi: 10.2340/00015555-0509.

Contoh Produk & Brand

Produk: 97 • International brands: 0
Produk
  • a.c. care Bees Sun Protection
    Cream • - • Topical • US • OTC
  • a.c.care Bees Sun Protection UV Moisturizer SPF 50
    Cream • - • Topical • US • OTC
  • Anthelios 50+
    Lotion • - • Topical • Canada • OTC • Approved
  • Anthelios Age Correct
    Cream • - • Topical • Canada • OTC • Approved
  • Anthelios Dermo-kids 50+
    Cream • - • Topical • Canada • OTC • Approved
  • Anthelios SPF 45
    Lotion • - • Topical • Canada • OTC • Approved
  • Anthelios Spray SPF 45
    Spray • - • Topical • Canada • OTC • Approved
  • Anthelios XL Melt-IN Cream
    Cream • - • Topical • Canada • OTC • Approved
Menampilkan 8 dari 97 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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