Peringatan Keamanan

An oral dose of 100-400 mg/kg or a parenteral dose of 5-15 mg/kg is believed to be fatal in humans L2757. Other studies propose that the fatal dose of quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is estimated to be between 1-3 grams L2757.

Some adverse effects associated with exposure to a quaternary ammonium compound like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride include the possibility of contact dermatitis, asthma or respiratory symptoms like runny nose, sore throat, or cough) F110. Allergic contact dermatitis is also a possibility F110. Direct eye and mucous membrane exposure resulting from inappropriate usage or administation of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride preparations can also occur. And as with most pharmaceutical agents, although ingestion and systemic absorption is possible, ingestion of appropriately dilute solutions of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is unlikely to be serious F110.

N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

DB11202

small molecule approved

Deskripsi

N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.

Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities and relatively little chance for systemic absorption and exposure, although the formal mechanism of action of quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is difficult to elucidate.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Readily accessible data regarding the half-life of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is not available.
Volume Distribusi Readily accessible data regarding the volume of distribution of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is not available.
Klirens (Clearance) Readily accessible data regarding the clearance of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is not available.

Absorpsi

Quaternary ammonium compounds are poorly absorbed by the oral route of administration L2757. At the same time, systemic effects from percutaneous absorption through intact skin is considered rare as well L2757. Nevertheless, although potentially minimal, systemic absorption is possible L2757.

Metabolisme

Readily accessible data regarding the metabolism of n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is not available.

Rute Eliminasi

As quaternary ammonium compounds like n-alkyl C12-C14 dimethyl ethylbenzyl ammonium chloride is poorly absorbed by the oral route, relatively large amounts of the agent that is absorbed is likely to be eliminated in the faeces L2757.

Interaksi Obat

0 Data
Tidak ada data.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 7548971
    Maris P: Modes of action of disinfectants. Rev Sci Tech. 1995 Mar;14(1):47-55.
  • PMID: 11556761
    Gupta AK, Ahmad I, Summerbell RC: Comparative efficacies of commonly used disinfectants and antifungal pharmaceutical spray preparations against dermatophytic fungi. Med Mycol. 2001 Aug;39(4):321-8.
  • PMID: 4292825
    Sidwell RW, Dixon GJ, McNeil E: Quantitative studies on fabrics as disseminators of viruses. 3. Persistence of vaccinia virus on fabrics impregnated with a virucidal agent. Appl Microbiol. 1967 Jul;15(4):921-7.

Contoh Produk & Brand

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Sekuens Gen/Protein (FASTA)

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