Oral LD50 of racepinephrine hydrochloride in mouse is 90 mg/kg MSDS.
Overdosage of epinephrine may cause extremely elevated arterial pressure, which may further lead to cerebrovascular hemorrhage, particularly in elderly patients. Peripheral vascular constriction in conjunction with cardiac stimulation may produce pulmonary oedema. Treatment consists of rapidly acting vasodilators or alpha-adrenergic blocking drugs and/or respiratory support. Transient bradycardia followed by tachycardia may also be observed, and may be accompanied by potentially fatal cardiac arrhythmias. remature ventricular contractions may appear within one minute after injection and may be followed by multifocal ventricular tachycardia (prefibrillation rhythm). Subsidence of the ventricular effects may be followed by atrial tachycardia and occasionally by atrioventricular block. In case of arrhythmias, treatment should involve administration of a beta adrenergic blocking drug such as propranolol. Overdosage may also produce extreme pallor and coldness of the skin, metabolic acidosis, and kidney failure, which should each be treated with suitable corrective measures FDA Label.
Racepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective ?- and ?-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath. It is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Racepinephrine may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Racepinephrine may decrease the antihypertensive activities of Ramipril. |
| Reserpine | Racepinephrine may decrease the antihypertensive activities of Reserpine. |
| Remikiren | Racepinephrine may decrease the antihypertensive activities of Remikiren. |
| Isradipine | Racepinephrine may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Racepinephrine may decrease the antihypertensive activities of Olmesartan. |
| Nitroprusside | Racepinephrine may decrease the antihypertensive activities of Nitroprusside. |
| Diltiazem | Racepinephrine may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Racepinephrine may decrease the antihypertensive activities of Minoxidil. |
| Treprostinil | Racepinephrine may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Racepinephrine may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Racepinephrine may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Racepinephrine may decrease the antihypertensive activities of Nisoldipine. |
| Fosinopril | Racepinephrine may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Racepinephrine may decrease the antihypertensive activities of Trandolapril. |
| Lercanidipine | Racepinephrine may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Racepinephrine may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Racepinephrine may decrease the antihypertensive activities of Bosentan. |
| Enalapril | Racepinephrine may decrease the antihypertensive activities of Enalapril. |
| Candoxatril | Racepinephrine may decrease the antihypertensive activities of Candoxatril. |
| Mecamylamine | Racepinephrine may decrease the antihypertensive activities of Mecamylamine. |
| Losartan | Racepinephrine may decrease the antihypertensive activities of Losartan. |
| Moexipril | Racepinephrine may decrease the antihypertensive activities of Moexipril. |
| Lisinopril | Racepinephrine may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Racepinephrine may decrease the antihypertensive activities of Nitroglycerin. |
| Metyrosine | Racepinephrine may decrease the antihypertensive activities of Metyrosine. |
| Cryptenamine | Racepinephrine may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Racepinephrine may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Racepinephrine may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Racepinephrine may decrease the antihypertensive activities of Fenoldopam. |
| Tadalafil | Racepinephrine may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Racepinephrine may decrease the antihypertensive activities of Eprosartan. |
| Quinapril | Racepinephrine may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Racepinephrine may decrease the antihypertensive activities of Telmisartan. |
| Methyldopa | Racepinephrine may decrease the antihypertensive activities of Methyldopa. |
| Irbesartan | Racepinephrine may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Racepinephrine may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Racepinephrine may decrease the antihypertensive activities of Deserpidine. |
| Pentolinium | Racepinephrine may decrease the antihypertensive activities of Pentolinium. |
| Trimethaphan | Racepinephrine may decrease the antihypertensive activities of Trimethaphan. |
| Captopril | Racepinephrine may decrease the antihypertensive activities of Captopril. |
| Epoprostenol | Racepinephrine may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Racepinephrine may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Racepinephrine may decrease the antihypertensive activities of Hydralazine. |
| Cilazapril | Racepinephrine may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Racepinephrine may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Racepinephrine may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Racepinephrine may decrease the antihypertensive activities of Mibefradil. |
| Debrisoquine | Racepinephrine may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Racepinephrine may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Racepinephrine may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Racepinephrine may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Racepinephrine may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Racepinephrine may decrease the antihypertensive activities of Pinacidil. |
| Temocapril | Racepinephrine may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Racepinephrine may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Racepinephrine may decrease the antihypertensive activities of Macitentan. |
| Hexamethonium | Racepinephrine may decrease the antihypertensive activities of Hexamethonium. |
| Aliskiren | Racepinephrine may decrease the antihypertensive activities of Aliskiren. |
| Nicorandil | Racepinephrine may decrease the antihypertensive activities of Nicorandil. |
| Lacidipine | Racepinephrine may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Racepinephrine may decrease the antihypertensive activities of Manidipine. |
| Rauwolfia serpentina root | Racepinephrine may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Racepinephrine may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Racepinephrine may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Racepinephrine may decrease the antihypertensive activities of Angiotensin 1-7. |
| Imidapril | Racepinephrine may decrease the antihypertensive activities of Imidapril. |
| BQ-123 | Racepinephrine may decrease the antihypertensive activities of BQ-123. |
| Tetrahydropalmatine | Racepinephrine may decrease the antihypertensive activities of Tetrahydropalmatine. |
| Dihydralazine | Racepinephrine may decrease the antihypertensive activities of Dihydralazine. |
| Zofenopril | Racepinephrine may decrease the antihypertensive activities of Zofenopril. |
| Guanoxan | Racepinephrine may decrease the antihypertensive activities of Guanoxan. |
| Delapril | Racepinephrine may decrease the antihypertensive activities of Delapril. |
| Vincamine | Racepinephrine may decrease the antihypertensive activities of Vincamine. |
| Linsidomine | Racepinephrine may decrease the antihypertensive activities of Linsidomine. |
| Guanoxabenz | Racepinephrine may decrease the antihypertensive activities of Guanoxabenz. |
| Tolonidine | Racepinephrine may decrease the antihypertensive activities of Tolonidine. |
| Endralazine | Racepinephrine may decrease the antihypertensive activities of Endralazine. |
| Cadralazine | Racepinephrine may decrease the antihypertensive activities of Cadralazine. |
| Bietaserpine | Racepinephrine may decrease the antihypertensive activities of Bietaserpine. |
| Guanazodine | Racepinephrine may decrease the antihypertensive activities of Guanazodine. |
| Methoserpidine | Racepinephrine may decrease the antihypertensive activities of Methoserpidine. |
| Guanoclor | Racepinephrine may decrease the antihypertensive activities of Guanoclor. |
| Candesartan | Racepinephrine may decrease the antihypertensive activities of Candesartan. |
| Dexniguldipine | Racepinephrine may decrease the antihypertensive activities of Dexniguldipine. |
| Tocopherylquinone | Racepinephrine may decrease the antihypertensive activities of Tocopherylquinone. |
| Benazeprilat | Racepinephrine may decrease the antihypertensive activities of Benazeprilat. |
| Fosinoprilat | Racepinephrine may decrease the antihypertensive activities of Fosinoprilat. |
| Ramiprilat | Racepinephrine may decrease the antihypertensive activities of Ramiprilat. |
| Perindoprilat | Racepinephrine may decrease the antihypertensive activities of Perindoprilat. |
| Quinaprilat | Racepinephrine may decrease the antihypertensive activities of Quinaprilat. |
| Felodipine | Racepinephrine may decrease the antihypertensive activities of Felodipine. |
| Levamlodipine | Racepinephrine may decrease the antihypertensive activities of Levamlodipine. |
| Azilsartan medoxomil | Racepinephrine may decrease the antihypertensive activities of Azilsartan medoxomil. |
| Diazoxide | Racepinephrine may decrease the antihypertensive activities of Diazoxide. |
| Linezolid | The risk or severity of hypertension can be increased when Linezolid is combined with Racepinephrine. |
| Benzylpenicilloyl polylysine | Racepinephrine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent. |
| Desmopressin | The risk or severity of hypertension can be increased when Desmopressin is combined with Racepinephrine. |
| Cyclosporine | The risk or severity of hypertension can be increased when Cyclosporine is combined with Racepinephrine. |
| Icosapent | The risk or severity of hypertension can be increased when Icosapent is combined with Racepinephrine. |