Peringatan Keamanan

Meradimate is considered safe but some studies have shown that it can increase the production of reactive oxygen species.T201

Meradimate

DB11096

small molecule approved

Deskripsi

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter.T200 It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.L1113, L2748

Struktur Molekul 2D

Berat 275.392

Wujud solid

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Volume Distribusi As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Klirens (Clearance) As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Absorpsi

Meradimate is not absorbed through the skin.^L2749

Metabolisme

As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Rute Eliminasi

As meradimate is not absorbed, this pharmacokinetic property is not relevant.

Interaksi Obat

0 Data

Tidak ada data.

Referensi & Sumber

Artikel (PubMed)

PMID: 23320122
Latha MS, Martis J, Shobha V, Sham Shinde R, Bangera S, Krishnankutty B, Bellary S, Varughese S, Rao P, Naveen Kumar BR: Sunscreening agents: a review. J Clin Aesthet Dermatol. 2013 Jan;6(1):16-26.

Textbook

Encyclopedia (2007). The encyclopedia of Ultraviolet Filters. Allured.
ISBN: 978-0-8493-3968-4
Draelos D. and Thaman L. (2006). Cosmetic formulation of skin care products. Taylor and Francis Group.
IARC Working Group (2001). IARC Handbooks of Cancer Prevention. WHO.

Link

Contoh Produk & Brand

Produk: 104 • International brands: 0

Produk

All Seasons Lip Balm

Stick • - • Topical • Canada • OTC • Approved
Aloe Up Medicated Lip Ice Sunscreen SPF 30

Lipstick • - • Topical • US • OTC
Aveda Botanical Kinetics Daily Light Guard

Cream • - • Topical • Canada • OTC • Approved
Biocorneum Plus Broad Spectrum SPF 30 Advanced Scar Treatment

Gel • - • Topical • US • OTC
BIOCORNEUM PLUS BROAD SPECTRUM SPF 30 ADVANCED SCAR TREATMENT gel

Gel • - • Topical • US • OTC
Blistex Lip Tone Balm

Ointment; Stick • - • Topical • Canada • OTC • Approved
Blistex Ultra Lip Balm

Ointment • - • Topical • Canada • OTC • Approved
Body Armor - SPF 30 Sunscreen

Cream • - • Topical • Canada • OTC • Approved

Menampilkan 8 dari 104 produk.

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.