Rat oral LD50, rabbit dermal LD50, and rat inhalation LC50 of sodium carboxymethyl cellulose are 27000 mg/kg, >2 g/kg, and >5800 mg/m^3 (4 hours), respectively MSDS.
Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining A33029. The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface A33029. Sodium carboxymethylcellulose is the most commonly used salt.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Tramadol | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Tramadol. |
| Trospium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Trospium. |
| Oxyphenonium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Oxyphenonium. |
| Benzatropine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Benzatropine. |
| Ziprasidone | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Ziprasidone. |
| Disopyramide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Disopyramide. |
| Amitriptyline | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Amitriptyline. |
| Ipratropium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Ipratropium. |
| Olanzapine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Olanzapine. |
| Metixene | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Metixene. |
| Terfenadine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Terfenadine. |
| Buclizine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Buclizine. |
| Clozapine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Clozapine. |
| Doxylamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Doxylamine. |
| Trihexyphenidyl | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Trihexyphenidyl. |
| Oxyphencyclimine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Oxyphencyclimine. |
| Procyclidine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Procyclidine. |
| Profenamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Profenamine. |
| Promazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Promazine. |
| Hyoscyamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Hyoscyamine. |
| Cyproheptadine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Cyproheptadine. |
| Imipramine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Imipramine. |
| Methscopolamine bromide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Methscopolamine bromide. |
| Chlorpromazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Chlorpromazine. |
| Gallamine triethiodide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Gallamine triethiodide. |
| Darifenacin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Darifenacin. |
| Tridihexethyl | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Tridihexethyl. |
| Triflupromazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Triflupromazine. |
| Anisotropine methylbromide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Anisotropine methylbromide. |
| Nortriptyline | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Nortriptyline. |
| Amoxapine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Amoxapine. |
| Atropine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Atropine. |
| Nicardipine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Nicardipine. |
| Pirenzepine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Pirenzepine. |
| Paroxetine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Paroxetine. |
| Homatropine methylbromide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Homatropine methylbromide. |
| Rocuronium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Rocuronium. |
| Scopolamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Scopolamine. |
| Benzquinamide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Benzquinamide. |
| Clidinium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Clidinium. |
| Propiomazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Propiomazine. |
| Propantheline | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Propantheline. |
| Dicyclomine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Dicyclomine. |
| Biperiden | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Biperiden. |
| Brompheniramine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Brompheniramine. |
| Flupentixol | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Flupentixol. |
| Cocaine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Cocaine. |
| Quinidine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Quinidine. |
| Maprotiline | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Maprotiline. |
| Methantheline | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Methantheline. |
| Cycrimine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Cycrimine. |
| Glycopyrronium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Glycopyrronium. |
| Tolterodine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Tolterodine. |
| Oxybutynin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Oxybutynin. |
| Promethazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Promethazine. |
| Diphenhydramine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Diphenhydramine. |
| Doxacurium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Doxacurium. |
| Doxepin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Doxepin. |
| Flavoxate | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Flavoxate. |
| Desipramine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Desipramine. |
| Orphenadrine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Orphenadrine. |
| Escitalopram | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Escitalopram. |
| Quetiapine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Quetiapine. |
| Mivacurium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Mivacurium. |
| Diphenidol | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Diphenidol. |
| Aripiprazole | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Aripiprazole. |
| Chlorprothixene | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Chlorprothixene. |
| Metocurine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Metocurine. |
| Pancuronium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Pancuronium. |
| Pipecuronium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Pipecuronium. |
| Methotrimeprazine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Methotrimeprazine. |
| Tiotropium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Tiotropium. |
| Solifenacin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Solifenacin. |
| Isopropamide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Isopropamide. |
| Rapacuronium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Rapacuronium. |
| Mepenzolate | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Mepenzolate. |
| Pizotifen | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Pizotifen. |
| Fesoterodine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Fesoterodine. |
| Hexocyclium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Hexocyclium. |
| Dimetindene | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Dimetindene. |
| Aclidinium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Aclidinium. |
| Dexetimide | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Dexetimide. |
| Benactyzine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Benactyzine. |
| Umeclidinium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Umeclidinium. |
| Trimebutine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Trimebutine. |
| Dosulepin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Dosulepin. |
| Imidafenacin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Imidafenacin. |
| Butylscopolamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Butylscopolamine. |
| Thonzylamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Thonzylamine. |
| Methscopolamine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Methscopolamine. |
| Revefenacin | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Revefenacin. |
| Oxitropium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Oxitropium. |
| Propiverine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Propiverine. |
| Batefenterol | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Batefenterol. |
| Mebeverine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Mebeverine. |
| Tropatepine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Tropatepine. |
| Prifinium | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Prifinium. |
| Piperidolate | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Piperidolate. |
| Benzilone | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Benzilone. |
| Difemerine | The therapeutic efficacy of Carboxymethylcellulose can be decreased when used in combination with Difemerine. |