Peringatan Keamanan

Rotavirus vaccine may produce severe diarrhea and vomiting as a result of rotavirus infection FDA Label. Post marketing reports suggest an increased risk of intussusception with rotavirus vaccine but this is unsupported by clinical data.

Rotavirus vaccine

DB10276

biotech approved

Deskripsi

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration.L1117 Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.L1116 Rotarix is a live attenuated vaccine containing the 89-12 human strain.Label Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection.L1117

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) The median duration of viral shedding was observed to be 10 days [FDA Label].
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

285 Data
Etanercept The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Etanercept.
Peginterferon alfa-2a The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Peginterferon alfa-2a.
Interferon alfa-n1 The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon alfa-n1.
Interferon alfa-n3 The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon alfa-n3.
Peginterferon alfa-2b The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Peginterferon alfa-2b.
Anakinra The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Anakinra.
Interferon gamma-1b The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon gamma-1b.
Interferon alfa-2a The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon alfa-2a.
Aldesleukin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Aldesleukin.
Adalimumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Adalimumab.
Gemtuzumab ozogamicin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Gemtuzumab ozogamicin.
Pegaspargase The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Pegaspargase.
Infliximab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Infliximab.
Interferon beta-1b The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon beta-1b.
Interferon alfacon-1 The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon alfacon-1.
Trastuzumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Trastuzumab.
Rituximab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Rituximab.
Basiliximab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Basiliximab.
Muromonab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Muromonab.
Ibritumomab tiuxetan The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Ibritumomab tiuxetan.
Tositumomab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Tositumomab.
Alemtuzumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Alemtuzumab.
Cyclosporine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Cyclosporine.
Alefacept The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Alefacept.
Efalizumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Efalizumab.
Antithymocyte immunoglobulin (rabbit) The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Antithymocyte immunoglobulin (rabbit).
Interferon alfa-2b The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Interferon alfa-2b.
Natalizumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Natalizumab.
Daclizumab The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Daclizumab.
Phenylalanine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Phenylalanine.
Bortezomib The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Bortezomib.
Cladribine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Cladribine.
Carmustine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Carmustine.
Amsacrine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Amsacrine.
Bleomycin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Bleomycin.
Chlorambucil The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Chlorambucil.
Raltitrexed The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Raltitrexed.
Mitomycin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Mitomycin.
Bexarotene The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Bexarotene.
Vindesine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Vindesine.
Floxuridine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Floxuridine.
Indomethacin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Indomethacin.
Tioguanine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Tioguanine.
Vinorelbine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Vinorelbine.
Dexrazoxane The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Dexrazoxane.
Sorafenib The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Sorafenib.
Streptozocin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Streptozocin.
Trifluridine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Trifluridine.
Gemcitabine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Gemcitabine.
Teniposide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Teniposide.
Epirubicin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Epirubicin.
Chloramphenicol The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Chloramphenicol.
Lenalidomide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Lenalidomide.
Altretamine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Altretamine.
Zidovudine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Zidovudine.
Cisplatin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Cisplatin.
Oxaliplatin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Oxaliplatin.
Cyclophosphamide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Cyclophosphamide.
Vincristine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Vincristine.
Fluorouracil The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Fluorouracil.
Propylthiouracil The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Propylthiouracil.
Pentostatin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Pentostatin.
Methotrexate The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Methotrexate.
Carbamazepine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Carbamazepine.
Vinblastine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Vinblastine.
Linezolid The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Linezolid.
Imatinib The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Imatinib.
Clofarabine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Clofarabine.
Pemetrexed The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Pemetrexed.
Mycophenolate mofetil The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Mycophenolate mofetil.
Daunorubicin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Daunorubicin.
Irinotecan The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Irinotecan.
Methimazole The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Methimazole.
Etoposide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Etoposide.
Sulfasalazine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Sulfasalazine.
Dacarbazine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Dacarbazine.
Temozolomide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Temozolomide.
Penicillamine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Penicillamine.
Tacrolimus The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Tacrolimus.
Sirolimus The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Sirolimus.
Mechlorethamine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Mechlorethamine.
Azacitidine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Azacitidine.
Carboplatin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Carboplatin.
Dactinomycin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Dactinomycin.
Azathioprine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Azathioprine.
Doxorubicin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Doxorubicin.
Hydroxyurea The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Hydroxyurea.
Busulfan The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Busulfan.
Mycophenolic acid The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Mycophenolic acid.
Topotecan The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Topotecan.
Mercaptopurine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Mercaptopurine.
Thalidomide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Thalidomide.
Melphalan The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Melphalan.
Fludarabine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Fludarabine.
Leflunomide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Leflunomide.
Flucytosine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Flucytosine.
Capecitabine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Capecitabine.
Procarbazine The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Procarbazine.
Arsenic trioxide The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Arsenic trioxide.
Idarubicin The therapeutic efficacy of Rotavirus vaccine can be decreased when used in combination with Idarubicin.

Referensi & Sumber

Contoh Produk & Brand

Produk: 36 • International brands: 0
Produk
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/ml • Oral • EU • Approved
  • Rotarix
    Suspension • 1000000 CCID50/1.5mL • Oral • Canada • Approved
  • Rotarix
    Solution • 1000 [CCID_50]/1mL • Oral • US • Approved
Menampilkan 8 dari 36 produk.

Sekuens Gen/Protein (FASTA)

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