Peringatan Keamanan

LC50: Not available.

Talc

DB09511

small molecule approved

Deskripsi

Talc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes.

Although talc has been widely used for decades, lawsuits that have come to the surface claim serious health complications linked to its use. In fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers by approximately 30 percent.

Struktur Molekul 2D

Berat 379.259
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) Intended for local use only.
Volume Distribusi Intended for local use only.
Klirens (Clearance) Intended for local use only.

Absorpsi

Intended for local use only.

Metabolisme

Intended for local use only.

Rute Eliminasi

Intended for local use only.

Interaksi Obat

57 Data
Calcitriol The serum concentration of Talc can be increased when it is combined with Calcitriol.
Calcifediol The serum concentration of Talc can be increased when it is combined with Calcifediol.
Ergocalciferol The serum concentration of Talc can be increased when it is combined with Ergocalciferol.
Cholecalciferol The serum concentration of Talc can be increased when it is combined with Cholecalciferol.
Paricalcitol The serum concentration of Talc can be increased when it is combined with Paricalcitol.
Dihydrotachysterol The serum concentration of Talc can be increased when it is combined with Dihydrotachysterol.
Alfacalcidol The serum concentration of Talc can be increased when it is combined with Alfacalcidol.
Seocalcitol The serum concentration of Talc can be increased when it is combined with Seocalcitol.
Inecalcitol The serum concentration of Talc can be increased when it is combined with Inecalcitol.
Becocalcidiol The serum concentration of Talc can be increased when it is combined with Becocalcidiol.
Eldecalcitol The serum concentration of Talc can be increased when it is combined with Eldecalcitol.
1alpha,24S-Dihydroxyvitamin D2 The serum concentration of Talc can be increased when it is combined with 1alpha,24S-Dihydroxyvitamin D2.
Elocalcitol The serum concentration of Talc can be increased when it is combined with Elocalcitol.
Maxacalcitol The serum concentration of Talc can be increased when it is combined with Maxacalcitol.
Doxercalciferol The serum concentration of Talc can be increased when it is combined with Doxercalciferol.
Vitamin D The serum concentration of Talc can be increased when it is combined with Vitamin D.
1alpha-Hydroxyvitamin D5 The serum concentration of Talc can be increased when it is combined with 1alpha-Hydroxyvitamin D5.
Previtamin D(3) The serum concentration of Talc can be increased when it is combined with Previtamin D(3).
Deferiprone Talc can cause a decrease in the absorption of Deferiprone resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eltrombopag Talc can cause a decrease in the absorption of Eltrombopag resulting in a reduced serum concentration and potentially a decrease in efficacy.
Moxifloxacin Talc can cause a decrease in the absorption of Moxifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Grepafloxacin Talc can cause a decrease in the absorption of Grepafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Enoxacin Talc can cause a decrease in the absorption of Enoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pefloxacin Talc can cause a decrease in the absorption of Pefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ciprofloxacin Talc can cause a decrease in the absorption of Ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Trovafloxacin Talc can cause a decrease in the absorption of Trovafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nalidixic acid Talc can cause a decrease in the absorption of Nalidixic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rosoxacin Talc can cause a decrease in the absorption of Rosoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cinoxacin Talc can cause a decrease in the absorption of Cinoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Lomefloxacin Talc can cause a decrease in the absorption of Lomefloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Gatifloxacin Talc can cause a decrease in the absorption of Gatifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Norfloxacin Talc can cause a decrease in the absorption of Norfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Levofloxacin Talc can cause a decrease in the absorption of Levofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ofloxacin Talc can cause a decrease in the absorption of Ofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sparfloxacin Talc can cause a decrease in the absorption of Sparfloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Temafloxacin Talc can cause a decrease in the absorption of Temafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fleroxacin Talc can cause a decrease in the absorption of Fleroxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Technetium Tc-99m ciprofloxacin Talc can cause a decrease in the absorption of Technetium Tc-99m ciprofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Garenoxacin Talc can cause a decrease in the absorption of Garenoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nemonoxacin Talc can cause a decrease in the absorption of Nemonoxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Flumequine Talc can cause a decrease in the absorption of Flumequine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Enrofloxacin Talc can cause a decrease in the absorption of Enrofloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Orbifloxacin Talc can cause a decrease in the absorption of Orbifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sarafloxacin Talc can cause a decrease in the absorption of Sarafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Difloxacin Talc can cause a decrease in the absorption of Difloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pazufloxacin Talc can cause a decrease in the absorption of Pazufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Prulifloxacin Talc can cause a decrease in the absorption of Prulifloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Delafloxacin Talc can cause a decrease in the absorption of Delafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sitafloxacin Talc can cause a decrease in the absorption of Sitafloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Oxolinic acid Talc can cause a decrease in the absorption of Oxolinic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Rufloxacin Talc can cause a decrease in the absorption of Rufloxacin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pipemidic acid Talc can cause a decrease in the absorption of Pipemidic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Doxycycline The absorption of Doxycycline can be decreased when combined with Talc.
Gemifloxacin The absorption of Gemifloxacin can be decreased when combined with Talc.
Dexpanthenol The serum concentration of Talc can be increased when it is combined with Dexpanthenol.
Roxadustat Talc can cause a decrease in the absorption of Roxadustat resulting in a reduced serum concentration and potentially a decrease in efficacy.
Vadadustat The serum concentration of Vadadustat can be decreased when it is combined with Talc.

Referensi & Sumber

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