Peringatan Keamanan

Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Its toxicity is related to the final product and not specific to Indium In-111 Chloride alone

Indium In-111 chloride

DB09490

small molecule approved

Deskripsi

Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for in vivo diagnostic imaging procedures and for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures. It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI.

Struktur Molekul 2D

Berat 217.26

Wujud -

Peta Jejaring Molekuler

Obat Target Gen Interaksi Enzim Transporter Carrier

Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

1. Pendahuluan & Konsep

Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).

2. Sumber Data (Validasi)

Data Obat: Diekstraksi dari elemen drugbank-id dan name pada skema XML DrugBank.
Target Protein: Diambil dari elemen targets/target yang memuat polipeptida sasaran.
Genetik: Disinkronisasi dari sub-elemen gene-name dan varian snp-effects.
Genetik: Jumlah titik node dibatasi pada maksimal 10 (Slice=10) interaksi untuk menghindari tumpukan data.

3. Algoritma Visualisasi

Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.

4. Legenda Visual

Obat Utama (Pusat Analisis)

Target Protein (Mekanisme)

Gen (Faktor Genetik)

Metode ini mendukung analisis Precision Medicine dan evaluasi risiko Drug-Drug Interaction (DDI).

Profil Farmakokinetik

Waktu Paruh (Half-Life) 2.8 days

Volume Distribusi Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Its volume of distribution is related to the final product and not specific to Indium In-111 Chloride alone

Klirens (Clearance) Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Its clearance is related to the final product and not specific to Indium In-111 Chloride alone

Absorpsi

Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Its absoption is related to the final product and not specific to Indium In-111 Chloride alone

Metabolisme

Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Its metabolism is related to the final product and not specific to Indium In-111 Chloride alone

Rute Eliminasi

Indium In-111 Chloride is a radioactive tracer for labeling monoclonal antibodies in certain preparations such as OncoScint, ProstaScint and Zevalin. Itsroute of elimination is related to the final product and not specific to Indium In-111 Chloride alone

Interaksi Makanan

1 Data

1. Drink plenty of fluids. Fluids will help remove excess radiation from the body when Indium In-111 chloride is used to radiolabel pentetreotide.

Interaksi Obat

0 Data

Tidak ada data.

Referensi & Sumber

Link

FDA label

Contoh Produk & Brand

Produk: 5 • International brands: 0

Produk

Indiclor

Solution • 5 mCi/0.5mL • Intravenous • US • Approved
Indium In 111 Chloride

Solution • 10 mCi/1mL • Intravenous • US • Approved
Indium In 111 Chloride

Solution • 10 mCi/1mL • Intravenous • US • Approved
Octreoscan

Kit • - • Intravenous • US • Approved
Octreoscan

Kit • - • Intravenous • US • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.