Peringatan Keamanan

LD50 not available.
Toxic effects in humans: Irritated skin, eye. Gastro intestinal irritation with nausea, vomiting, diarrhea, abdominal discomfort

Dipotassium phosphate

DB09414

small molecule approved

Deskripsi

Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.

Struktur Molekul 2D

Berat 174.1759
Wujud -

Peta Jejaring Molekuler
Legenda: Obat • Target • Gen • Enzim • (Panah → menunjukkan arah efek / relasi) • Transporter • Carrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) In healthy children with phosphate overdose, half-life was 4.8 to 10.6 hours, and was prolonged to 17 hours in a child with renal insufficiency.
Volume Distribusi Distribution is largely intracellular, but it is the intravascular concentration that is primarily responsible for toxicity.
Klirens (Clearance) Phosphates are rapidly cleared by dialysis.

Absorpsi

Potassium salts are well absorbed from gastro intestinal tract. Net phosphorus absorption may occur in the small intestine in some species but is primarily a function of the colon in horses.

Metabolisme

Phosphate is a major intracellular anion which participates in providing energy for metabolism of substances and contributes to important metabolic and enzymatic reactions in almost all organs and tissues.

Rute Eliminasi

Potassium is excreted primarily by kidney.

Interaksi Obat

649 Data
Tramadol The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Tramadol.
Trospium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Trospium.
Oxyphenonium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Oxyphenonium.
Benzatropine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Benzatropine.
Ziprasidone The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Ziprasidone.
Disopyramide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Disopyramide.
Amitriptyline The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Amitriptyline.
Ipratropium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Ipratropium.
Olanzapine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Olanzapine.
Metixene The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Metixene.
Terfenadine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Terfenadine.
Buclizine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Buclizine.
Clozapine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Clozapine.
Doxylamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Doxylamine.
Trihexyphenidyl The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Trihexyphenidyl.
Oxyphencyclimine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Oxyphencyclimine.
Procyclidine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Procyclidine.
Profenamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Profenamine.
Promazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Promazine.
Hyoscyamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Hyoscyamine.
Cyproheptadine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Cyproheptadine.
Imipramine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Imipramine.
Methscopolamine bromide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Methscopolamine bromide.
Chlorpromazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Chlorpromazine.
Gallamine triethiodide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Gallamine triethiodide.
Darifenacin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Darifenacin.
Tridihexethyl The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Tridihexethyl.
Triflupromazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Triflupromazine.
Anisotropine methylbromide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Anisotropine methylbromide.
Nortriptyline The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Nortriptyline.
Amoxapine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Amoxapine.
Atropine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Atropine.
Pirenzepine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Pirenzepine.
Paroxetine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Paroxetine.
Homatropine methylbromide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Homatropine methylbromide.
Rocuronium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Rocuronium.
Scopolamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Scopolamine.
Benzquinamide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Benzquinamide.
Clidinium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Clidinium.
Propiomazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Propiomazine.
Propantheline The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Propantheline.
Dicyclomine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Dicyclomine.
Biperiden The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Biperiden.
Brompheniramine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Brompheniramine.
Flupentixol The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Flupentixol.
Cocaine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Cocaine.
Quinidine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Quinidine.
Maprotiline The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Maprotiline.
Methantheline The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Methantheline.
Cycrimine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Cycrimine.
Glycopyrronium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Glycopyrronium.
Tolterodine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Tolterodine.
Oxybutynin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Oxybutynin.
Promethazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Promethazine.
Diphenhydramine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Diphenhydramine.
Doxacurium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Doxacurium.
Doxepin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Doxepin.
Flavoxate The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Flavoxate.
Desipramine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Desipramine.
Orphenadrine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Orphenadrine.
Escitalopram The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Escitalopram.
Quetiapine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Quetiapine.
Mivacurium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Mivacurium.
Diphenidol The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Diphenidol.
Aripiprazole The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Aripiprazole.
Chlorprothixene The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Chlorprothixene.
Metocurine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Metocurine.
Pancuronium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Pancuronium.
Pipecuronium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Pipecuronium.
Methotrimeprazine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Methotrimeprazine.
Tiotropium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Tiotropium.
Solifenacin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Solifenacin.
Isopropamide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Isopropamide.
Rapacuronium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Rapacuronium.
Mepenzolate The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Mepenzolate.
Pizotifen The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Pizotifen.
Fesoterodine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Fesoterodine.
Hexocyclium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Hexocyclium.
Dimetindene The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Dimetindene.
Aclidinium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Aclidinium.
Dexetimide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Dexetimide.
Benactyzine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Benactyzine.
Umeclidinium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Umeclidinium.
Dosulepin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Dosulepin.
Imidafenacin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Imidafenacin.
Butylscopolamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Butylscopolamine.
Thonzylamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Thonzylamine.
Methscopolamine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Methscopolamine.
Revefenacin The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Revefenacin.
Oxitropium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Oxitropium.
Propiverine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Propiverine.
Batefenterol The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Batefenterol.
Mebeverine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Mebeverine.
Tropatepine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Tropatepine.
Prifinium The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Prifinium.
Piperidolate The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Piperidolate.
Benzilone The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Benzilone.
Difemerine The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Difemerine.
Phenglutarimide The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Phenglutarimide.
Mazaticol The therapeutic efficacy of Dipotassium phosphate can be decreased when used in combination with Mazaticol.

Referensi & Sumber

Contoh Produk & Brand

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