Mouse LD50 60mg/kg ( intravenous )
Rat LD50 : 87mh/kg ( intravenous)
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benzeindolium, 2-7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Cyclosporine | Cyclosporine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Troglitazone | Troglitazone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Erythromycin | Erythromycin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Reserpine | Reserpine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Progesterone | Progesterone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Chlorpromazine | Chlorpromazine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Celecoxib | Celecoxib may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Cimetidine | Cimetidine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Bosentan | Bosentan may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Tamoxifen | Tamoxifen may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Quinidine | Quinidine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Tipranavir | Tipranavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ethinylestradiol | Ethinylestradiol may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Glyburide | Glyburide may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ketoconazole | Ketoconazole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ursodeoxycholic acid | Ursodeoxycholic acid may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Cholic Acid | Cholic Acid may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Fusidic acid | Fusidic acid may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Simeprevir | Simeprevir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Lenvatinib | Lenvatinib may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Valinomycin | Valinomycin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Olmesartan | Olmesartan may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Pralsetinib | Pralsetinib may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Phenobarbital | Phenobarbital may increase the excretion rate of Indocyanine green acid form which could result in a lower serum level and potentially a reduction in efficacy. |
| Dexamethasone | Dexamethasone may increase the excretion rate of Indocyanine green acid form which could result in a lower serum level and potentially a reduction in efficacy. |
| Deoxycholic acid | Deoxycholic acid may increase the excretion rate of Indocyanine green acid form which could result in a lower serum level and potentially a reduction in efficacy. |
| Taurocholic acid | Taurocholic acid may increase the excretion rate of Indocyanine green acid form which could result in a lower serum level and potentially a reduction in efficacy. |
| Dexamethasone acetate | Dexamethasone acetate may increase the excretion rate of Indocyanine green acid form which could result in a lower serum level and potentially a reduction in efficacy. |
| Pravastatin | Pravastatin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Fluvoxamine | Fluvoxamine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nelfinavir | Nelfinavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Glimepiride | Glimepiride may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Indinavir | Indinavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ranolazine | Ranolazine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Diethylstilbestrol | Diethylstilbestrol may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Isradipine | Isradipine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Flucloxacillin | Flucloxacillin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Indomethacin | Indomethacin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Atenolol | Atenolol may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Terfenadine | Terfenadine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Rosiglitazone | Rosiglitazone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Cerivastatin | Cerivastatin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Loratadine | Loratadine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ritonavir | Ritonavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Atropine | Atropine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Diclofenac | Diclofenac may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Imatinib | Imatinib may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nicardipine | Nicardipine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Efavirenz | Efavirenz may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Simvastatin | Simvastatin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Fluorescein | Fluorescein may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nitrofurantoin | Nitrofurantoin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Naproxen | Naproxen may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Disulfiram | Disulfiram may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Cefaclor | Cefaclor may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Mifepristone | Mifepristone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Tinidazole | Tinidazole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Repaglinide | Repaglinide may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Telmisartan | Telmisartan may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ezetimibe | Ezetimibe may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Dipyridamole | Dipyridamole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Sulfamethoxazole | Sulfamethoxazole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Felodipine | Felodipine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Fenofibrate | Fenofibrate may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nitrendipine | Nitrendipine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Glipizide | Glipizide may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Atazanavir | Atazanavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Atorvastatin | Atorvastatin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Rosuvastatin | Rosuvastatin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nifedipine | Nifedipine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Sulfinpyrazone | Sulfinpyrazone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Nefazodone | Nefazodone may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Ofloxacin | Ofloxacin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Clarithromycin | Clarithromycin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Budesonide | Budesonide may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Saquinavir | Saquinavir may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Prasterone sulfate | Prasterone sulfate may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Benzbromarone | Indocyanine green acid form may decrease the excretion rate of Benzbromarone which could result in a higher serum level. |
| Pilsicainide | Indocyanine green acid form may decrease the excretion rate of Pilsicainide which could result in a higher serum level. |
| Dihydroergocristine | Indocyanine green acid form may decrease the excretion rate of Dihydroergocristine which could result in a higher serum level. |
| Glycyrrhizic acid | Indocyanine green acid form may decrease the excretion rate of Glycyrrhizic acid which could result in a higher serum level. |
| Glycochenodeoxycholic Acid | Glycochenodeoxycholic Acid may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Belantamab mafodotin | Indocyanine green acid form may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level. |
| Vinblastine | Vinblastine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Vincristine | Vincristine may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Astemizole | Astemizole may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Doxorubicin | Doxorubicin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Digoxin | Digoxin may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |
| Paclitaxel | Paclitaxel may decrease the excretion rate of Indocyanine green acid form which could result in a higher serum level. |