Norethynodrel

DB09371

small molecule approved

Deskripsi

A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL.

Struktur Molekul 2D

Berat 298.426
Wujud -

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

538 Data
Acitretin The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Acitretin.
Aprepitant The serum concentration of Norethynodrel can be decreased when it is combined with Aprepitant.
Atazanavir The serum concentration of Norethynodrel can be increased when it is combined with Atazanavir.
Boceprevir The serum concentration of Norethynodrel can be increased when it is combined with Boceprevir.
Prucalopride The serum concentration of Norethynodrel can be decreased when it is combined with Prucalopride.
Sugammadex The serum concentration of Norethynodrel can be decreased when it is combined with Sugammadex.
Thalidomide Norethynodrel may increase the thrombogenic activities of Thalidomide.
Ulipristal The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Ulipristal.
Ursodeoxycholic acid The therapeutic efficacy of Ursodeoxycholic acid can be decreased when used in combination with Norethynodrel.
Glycochenodeoxycholic Acid The therapeutic efficacy of Glycochenodeoxycholic Acid can be decreased when used in combination with Norethynodrel.
Cholic Acid The therapeutic efficacy of Cholic Acid can be decreased when used in combination with Norethynodrel.
Glycocholic acid The therapeutic efficacy of Glycocholic acid can be decreased when used in combination with Norethynodrel.
Deoxycholic acid The therapeutic efficacy of Deoxycholic acid can be decreased when used in combination with Norethynodrel.
Taurocholic acid The therapeutic efficacy of Taurocholic acid can be decreased when used in combination with Norethynodrel.
Obeticholic acid The therapeutic efficacy of Obeticholic acid can be decreased when used in combination with Norethynodrel.
Tauroursodeoxycholic acid The therapeutic efficacy of Tauroursodeoxycholic acid can be decreased when used in combination with Norethynodrel.
Bamet-UD2 The therapeutic efficacy of Bamet-UD2 can be decreased when used in combination with Norethynodrel.
cis-Diamminechlorocholylglycinateplatinum(II) The therapeutic efficacy of cis-Diamminechlorocholylglycinateplatinum(II) can be decreased when used in combination with Norethynodrel.
Dehydrocholic acid The therapeutic efficacy of Dehydrocholic acid can be decreased when used in combination with Norethynodrel.
Hyodeoxycholic Acid The therapeutic efficacy of Hyodeoxycholic Acid can be decreased when used in combination with Norethynodrel.
Aramchol The therapeutic efficacy of Aramchol can be decreased when used in combination with Norethynodrel.
Ox bile extract The therapeutic efficacy of Ox bile extract can be decreased when used in combination with Norethynodrel.
Chenodeoxycholic acid The therapeutic efficacy of Chenodeoxycholic acid can be decreased when used in combination with Norethynodrel.
Taurochenodeoxycholic acid The therapeutic efficacy of Taurochenodeoxycholic acid can be decreased when used in combination with Norethynodrel.
Tranexamic acid Norethynodrel may increase the thrombogenic activities of Tranexamic acid.
Clobazam The serum concentration of Norethynodrel can be decreased when it is combined with Clobazam.
Colestipol Colestipol can cause a decrease in the absorption of Norethynodrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Sevelamer Sevelamer can cause a decrease in the absorption of Norethynodrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Colesevelam Colesevelam can cause a decrease in the absorption of Norethynodrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Cholestyramine Cholestyramine can cause a decrease in the absorption of Norethynodrel resulting in a reduced serum concentration and potentially a decrease in efficacy.
Griseofulvin The metabolism of Norethynodrel can be increased when combined with Griseofulvin.
Tixocortol The serum concentration of Tixocortol can be increased when it is combined with Norethynodrel.
Fluocortin The serum concentration of Fluocortin can be increased when it is combined with Norethynodrel.
Fluperolone The serum concentration of Fluperolone can be increased when it is combined with Norethynodrel.
Fluclorolone The serum concentration of Fluclorolone can be increased when it is combined with Norethynodrel.
Flunisolide The serum concentration of Flunisolide can be increased when it is combined with Norethynodrel.
Beclomethasone dipropionate The serum concentration of Beclomethasone dipropionate can be increased when it is combined with Norethynodrel.
Betamethasone The serum concentration of Betamethasone can be increased when it is combined with Norethynodrel.
Fluocinolone acetonide The serum concentration of Fluocinolone acetonide can be increased when it is combined with Norethynodrel.
Triamcinolone The serum concentration of Triamcinolone can be increased when it is combined with Norethynodrel.
Prednisone The serum concentration of Prednisone can be increased when it is combined with Norethynodrel.
Hydrocortisone The serum concentration of Hydrocortisone can be increased when it is combined with Norethynodrel.
Prednisolone The serum concentration of Prednisolone can be increased when it is combined with Norethynodrel.
Methylprednisolone The serum concentration of Methylprednisolone can be increased when it is combined with Norethynodrel.
Corticotropin The serum concentration of Corticotropin can be increased when it is combined with Norethynodrel.
Cortisone acetate The serum concentration of Cortisone acetate can be increased when it is combined with Norethynodrel.
Fluprednidene The serum concentration of Fluprednidene can be increased when it is combined with Norethynodrel.
Meprednisone The serum concentration of Meprednisone can be increased when it is combined with Norethynodrel.
Dexamethasone isonicotinate The serum concentration of Dexamethasone isonicotinate can be increased when it is combined with Norethynodrel.
Deflazacort The serum concentration of Deflazacort can be increased when it is combined with Norethynodrel.
Cortivazol The serum concentration of Cortivazol can be increased when it is combined with Norethynodrel.
Prednylidene The serum concentration of Prednylidene can be increased when it is combined with Norethynodrel.
Cloprednol The serum concentration of Cloprednol can be increased when it is combined with Norethynodrel.
Mometasone furoate The serum concentration of Mometasone furoate can be increased when it is combined with Norethynodrel.
Hydrocortisone acetate The serum concentration of Hydrocortisone acetate can be increased when it is combined with Norethynodrel.
Hydrocortisone succinate The serum concentration of Hydrocortisone succinate can be increased when it is combined with Norethynodrel.
Prednisolone phosphate The serum concentration of Prednisolone phosphate can be increased when it is combined with Norethynodrel.
Prednisolone hemisuccinate The serum concentration of Prednisolone hemisuccinate can be increased when it is combined with Norethynodrel.
Methylprednisolone hemisuccinate The serum concentration of Methylprednisolone hemisuccinate can be increased when it is combined with Norethynodrel.
Prednisone acetate The serum concentration of Prednisone acetate can be increased when it is combined with Norethynodrel.
Clocortolone acetate The serum concentration of Clocortolone acetate can be increased when it is combined with Norethynodrel.
Melengestrol acetate The serum concentration of Melengestrol acetate can be increased when it is combined with Norethynodrel.
Betamethasone phosphate The serum concentration of Betamethasone phosphate can be increased when it is combined with Norethynodrel.
Cortisone The serum concentration of Cortisone can be increased when it is combined with Norethynodrel.
Fluticasone propionate The serum concentration of Fluticasone propionate can be increased when it is combined with Norethynodrel.
Fludrocortisone The serum concentration of Fludrocortisone can be increased when it is combined with Norethynodrel.
Trilostane The serum concentration of Trilostane can be increased when it is combined with Norethynodrel.
Budesonide The serum concentration of Budesonide can be increased when it is combined with Norethynodrel.
Dexamethasone The serum concentration of Dexamethasone can be increased when it is combined with Norethynodrel.
Paramethasone The serum concentration of Paramethasone can be increased when it is combined with Norethynodrel.
Ciclesonide The serum concentration of Ciclesonide can be increased when it is combined with Norethynodrel.
Aldosterone The serum concentration of Aldosterone can be increased when it is combined with Norethynodrel.
Fluticasone furoate The serum concentration of Fluticasone furoate can be increased when it is combined with Norethynodrel.
Fluprednisolone The serum concentration of Fluprednisolone can be increased when it is combined with Norethynodrel.
Melengestrol The serum concentration of Melengestrol can be increased when it is combined with Norethynodrel.
Fluticasone The serum concentration of Fluticasone can be increased when it is combined with Norethynodrel.
Hydrocortisone cypionate The serum concentration of Hydrocortisone cypionate can be increased when it is combined with Norethynodrel.
Clobetasol propionate The serum concentration of Clobetasol propionate can be increased when it is combined with Norethynodrel.
Fluocinonide The serum concentration of Fluocinonide can be increased when it is combined with Norethynodrel.
Hydrocortisone butyrate The serum concentration of Hydrocortisone butyrate can be increased when it is combined with Norethynodrel.
Desoximetasone The serum concentration of Desoximetasone can be increased when it is combined with Norethynodrel.
Mometasone The serum concentration of Mometasone can be increased when it is combined with Norethynodrel.
Fluocortolone The serum concentration of Fluocortolone can be increased when it is combined with Norethynodrel.
Prednisolone acetate The serum concentration of Prednisolone acetate can be increased when it is combined with Norethynodrel.
Fluorometholone The serum concentration of Fluorometholone can be increased when it is combined with Norethynodrel.
Difluocortolone The serum concentration of Difluocortolone can be increased when it is combined with Norethynodrel.
Flumethasone The serum concentration of Flumethasone can be increased when it is combined with Norethynodrel.
Methylprednisolone aceponate The serum concentration of Methylprednisolone aceponate can be increased when it is combined with Norethynodrel.
Vitamin A The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Vitamin A.
Bexarotene The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Bexarotene.
Alitretinoin The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Alitretinoin.
Tretinoin The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Tretinoin.
Tazarotene The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Tazarotene.
Etretinate The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Etretinate.
Isotretinoin The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Isotretinoin.
4-Oxoretinol The therapeutic efficacy of Norethynodrel can be decreased when used in combination with 4-Oxoretinol.
Fenretinide The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Fenretinide.
Ro 12-7310 The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Ro 12-7310.
Zuretinol acetate The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Zuretinol acetate.
Motretinide The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Motretinide.

Target Protein

Estrogen receptor ESR1
Androgen receptor AR
Sex hormone-binding globulin SHBG

Referensi & Sumber

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