Carindacillin

DB09319

small molecule approved investigational

Deskripsi

Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.

Struktur Molekul 2D

Berat 494.56
Wujud solid

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Obat

192 Data
Methotrexate The excretion of Methotrexate can be decreased when combined with Carindacillin.
Probenecid The excretion of Carindacillin can be decreased when combined with Probenecid.
Doxycycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Doxycycline.
Lymecycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Lymecycline.
Clomocycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Clomocycline.
Tigecycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Tigecycline.
Oxytetracycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Oxytetracycline.
Demeclocycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Demeclocycline.
Tetracycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Tetracycline.
Metacycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Metacycline.
Minocycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Minocycline.
Rolitetracycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Rolitetracycline.
Sarecycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Sarecycline.
Eravacycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Eravacycline.
Omadacycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Omadacycline.
Penimepicycline The therapeutic efficacy of Carindacillin can be decreased when used in combination with Penimepicycline.
Mycophenolate mofetil The serum concentration of Mycophenolate mofetil can be decreased when it is combined with Carindacillin.
Mycophenolic acid The serum concentration of Mycophenolic acid can be decreased when it is combined with Carindacillin.
Picosulfuric acid The therapeutic efficacy of Picosulfuric acid can be decreased when used in combination with Carindacillin.
Dicoumarol Carindacillin may increase the anticoagulant activities of Dicoumarol.
Phenindione Carindacillin may increase the anticoagulant activities of Phenindione.
Warfarin Carindacillin may increase the anticoagulant activities of Warfarin.
Phenprocoumon Carindacillin may increase the anticoagulant activities of Phenprocoumon.
Acenocoumarol Carindacillin may increase the anticoagulant activities of Acenocoumarol.
4-hydroxycoumarin Carindacillin may increase the anticoagulant activities of 4-hydroxycoumarin.
Coumarin Carindacillin may increase the anticoagulant activities of Coumarin.
(R)-warfarin Carindacillin may increase the anticoagulant activities of (R)-warfarin.
Ethyl biscoumacetate Carindacillin may increase the anticoagulant activities of Ethyl biscoumacetate.
Fluindione Carindacillin may increase the anticoagulant activities of Fluindione.
Clorindione Carindacillin may increase the anticoagulant activities of Clorindione.
Diphenadione Carindacillin may increase the anticoagulant activities of Diphenadione.
Tioclomarol Carindacillin may increase the anticoagulant activities of Tioclomarol.
(S)-Warfarin Carindacillin may increase the anticoagulant activities of (S)-Warfarin.
Diethylstilbestrol The therapeutic efficacy of Diethylstilbestrol can be decreased when used in combination with Carindacillin.
Etonogestrel The therapeutic efficacy of Etonogestrel can be decreased when used in combination with Carindacillin.
Desogestrel The therapeutic efficacy of Desogestrel can be decreased when used in combination with Carindacillin.
Megestrol acetate The therapeutic efficacy of Megestrol acetate can be decreased when used in combination with Carindacillin.
Levonorgestrel The therapeutic efficacy of Levonorgestrel can be decreased when used in combination with Carindacillin.
Progesterone The therapeutic efficacy of Progesterone can be decreased when used in combination with Carindacillin.
Medroxyprogesterone acetate The therapeutic efficacy of Medroxyprogesterone acetate can be decreased when used in combination with Carindacillin.
Norethisterone The therapeutic efficacy of Norethisterone can be decreased when used in combination with Carindacillin.
Estradiol The therapeutic efficacy of Estradiol can be decreased when used in combination with Carindacillin.
Ethynodiol diacetate The therapeutic efficacy of Ethynodiol diacetate can be decreased when used in combination with Carindacillin.
Mifepristone The therapeutic efficacy of Mifepristone can be decreased when used in combination with Carindacillin.
Norgestimate The therapeutic efficacy of Norgestimate can be decreased when used in combination with Carindacillin.
Ethinylestradiol The therapeutic efficacy of Ethinylestradiol can be decreased when used in combination with Carindacillin.
Mestranol The therapeutic efficacy of Mestranol can be decreased when used in combination with Carindacillin.
Drospirenone The therapeutic efficacy of Drospirenone can be decreased when used in combination with Carindacillin.
Estrone sulfate The therapeutic efficacy of Estrone sulfate can be decreased when used in combination with Carindacillin.
Octylphenoxy polyethoxyethanol The therapeutic efficacy of Octylphenoxy polyethoxyethanol can be decreased when used in combination with Carindacillin.
Cyproterone acetate The therapeutic efficacy of Cyproterone acetate can be decreased when used in combination with Carindacillin.
Trestolone The therapeutic efficacy of Trestolone can be decreased when used in combination with Carindacillin.
Norelgestromin The therapeutic efficacy of Norelgestromin can be decreased when used in combination with Carindacillin.
Gestodene The therapeutic efficacy of Gestodene can be decreased when used in combination with Carindacillin.
Hydroxyprogesterone caproate The therapeutic efficacy of Hydroxyprogesterone caproate can be decreased when used in combination with Carindacillin.
Ulipristal The therapeutic efficacy of Ulipristal can be decreased when used in combination with Carindacillin.
Dienogest The therapeutic efficacy of Dienogest can be decreased when used in combination with Carindacillin.
Norethynodrel The therapeutic efficacy of Norethynodrel can be decreased when used in combination with Carindacillin.
Norgestrel The therapeutic efficacy of Norgestrel can be decreased when used in combination with Carindacillin.
Cloprostenol The therapeutic efficacy of Cloprostenol can be decreased when used in combination with Carindacillin.
Gestrinone The therapeutic efficacy of Gestrinone can be decreased when used in combination with Carindacillin.
Nomegestrol The therapeutic efficacy of Nomegestrol can be decreased when used in combination with Carindacillin.
Lynestrenol The therapeutic efficacy of Lynestrenol can be decreased when used in combination with Carindacillin.
Gossypol The therapeutic efficacy of Gossypol can be decreased when used in combination with Carindacillin.
Ormeloxifene The therapeutic efficacy of Ormeloxifene can be decreased when used in combination with Carindacillin.
Chlormadinone The therapeutic efficacy of Chlormadinone can be decreased when used in combination with Carindacillin.
Norgestrienone The therapeutic efficacy of Norgestrienone can be decreased when used in combination with Carindacillin.
Quingestanol The therapeutic efficacy of Quingestanol can be decreased when used in combination with Carindacillin.
Demegestone The therapeutic efficacy of Demegestone can be decreased when used in combination with Carindacillin.
Etynodiol The therapeutic efficacy of Etynodiol can be decreased when used in combination with Carindacillin.
Testosterone enanthate The therapeutic efficacy of Testosterone enanthate can be decreased when used in combination with Carindacillin.
Estradiol benzoate The therapeutic efficacy of Estradiol benzoate can be decreased when used in combination with Carindacillin.
Estradiol cypionate The therapeutic efficacy of Estradiol cypionate can be decreased when used in combination with Carindacillin.
Estradiol valerate The therapeutic efficacy of Estradiol valerate can be decreased when used in combination with Carindacillin.
Nomegestrol acetate The therapeutic efficacy of Nomegestrol acetate can be decreased when used in combination with Carindacillin.
Norethindrone enanthate The therapeutic efficacy of Norethindrone enanthate can be decreased when used in combination with Carindacillin.
Capreomycin The serum concentration of Capreomycin can be decreased when it is combined with Carindacillin.
Framycetin The serum concentration of Framycetin can be decreased when it is combined with Carindacillin.
Amikacin The serum concentration of Amikacin can be decreased when it is combined with Carindacillin.
Tobramycin The serum concentration of Tobramycin can be decreased when it is combined with Carindacillin.
Gentamicin The serum concentration of Gentamicin can be decreased when it is combined with Carindacillin.
Netilmicin The serum concentration of Netilmicin can be decreased when it is combined with Carindacillin.
Neomycin The serum concentration of Neomycin can be decreased when it is combined with Carindacillin.
Streptomycin The serum concentration of Streptomycin can be decreased when it is combined with Carindacillin.
Kanamycin The serum concentration of Kanamycin can be decreased when it is combined with Carindacillin.
Paromomycin The serum concentration of Paromomycin can be decreased when it is combined with Carindacillin.
Ribostamycin The serum concentration of Ribostamycin can be decreased when it is combined with Carindacillin.
Geneticin The serum concentration of Geneticin can be decreased when it is combined with Carindacillin.
Apramycin The serum concentration of Apramycin can be decreased when it is combined with Carindacillin.
Gentamicin C1a The serum concentration of Gentamicin C1a can be decreased when it is combined with Carindacillin.
Neamine The serum concentration of Neamine can be decreased when it is combined with Carindacillin.
Arbekacin The serum concentration of Arbekacin can be decreased when it is combined with Carindacillin.
Puromycin The serum concentration of Puromycin can be decreased when it is combined with Carindacillin.
Dihydrostreptomycin The serum concentration of Dihydrostreptomycin can be decreased when it is combined with Carindacillin.
Hygromycin B The serum concentration of Hygromycin B can be decreased when it is combined with Carindacillin.
Sisomicin The serum concentration of Sisomicin can be decreased when it is combined with Carindacillin.
Plazomicin The serum concentration of Plazomicin can be decreased when it is combined with Carindacillin.
Isepamicin The serum concentration of Isepamicin can be decreased when it is combined with Carindacillin.
Colistin The serum concentration of Colistin can be decreased when it is combined with Carindacillin.
BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Carindacillin.

Target Protein

Penicillin-binding protein dacA

Referensi & Sumber

Artikel (PubMed)
  • PMID: 4558137
    English AR, Retsema JA, Ray VA, Lynch JE: Carbenicillin indanyl sodium, an orally active derivative of carbenicillin. Antimicrob Agents Chemother. 1972 Mar;1(3):185-91.

Contoh Produk & Brand

Produk: 1 • International brands: 0
Produk
  • Geocillin
    Tablet, film coated • 382 mg/1 • Oral • US • Approved

Sekuens Gen/Protein (FASTA)

Sekuens dimuat saat dibutuhkan agar halaman tetap ringan.
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