The LD50 of calcium polycarbophil in young adult rats approximated 20 g/kg.
Polycarbophil calcium is a synthetic polymer manufactured from the cross-linking of polyacrylic acid with divinyl glycol and a calcium counter-ion.
Polycarbophil calcium is a stool stabilizer used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea.
Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps. It is insoluble in water, dilute acids, and dilute alkali. The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and does not cause gastrointestinal irritation.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Tramadol | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Tramadol. |
| Trospium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Trospium. |
| Oxyphenonium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Oxyphenonium. |
| Benzatropine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Benzatropine. |
| Ziprasidone | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Ziprasidone. |
| Disopyramide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Disopyramide. |
| Amitriptyline | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Amitriptyline. |
| Ipratropium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Ipratropium. |
| Olanzapine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Olanzapine. |
| Metixene | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Metixene. |
| Terfenadine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Terfenadine. |
| Buclizine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Buclizine. |
| Clozapine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Clozapine. |
| Doxylamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Doxylamine. |
| Trihexyphenidyl | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Trihexyphenidyl. |
| Oxyphencyclimine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Oxyphencyclimine. |
| Procyclidine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Procyclidine. |
| Profenamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Profenamine. |
| Promazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Promazine. |
| Hyoscyamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Hyoscyamine. |
| Cyproheptadine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Cyproheptadine. |
| Imipramine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Imipramine. |
| Methscopolamine bromide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Methscopolamine bromide. |
| Chlorpromazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Chlorpromazine. |
| Gallamine triethiodide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Gallamine triethiodide. |
| Darifenacin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Darifenacin. |
| Tridihexethyl | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Tridihexethyl. |
| Triflupromazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Triflupromazine. |
| Anisotropine methylbromide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Anisotropine methylbromide. |
| Nortriptyline | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Nortriptyline. |
| Amoxapine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Amoxapine. |
| Atropine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Atropine. |
| Nicardipine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Nicardipine. |
| Pirenzepine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Pirenzepine. |
| Paroxetine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Paroxetine. |
| Homatropine methylbromide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Homatropine methylbromide. |
| Rocuronium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Rocuronium. |
| Scopolamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Scopolamine. |
| Benzquinamide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Benzquinamide. |
| Clidinium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Clidinium. |
| Propiomazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Propiomazine. |
| Propantheline | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Propantheline. |
| Dicyclomine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Dicyclomine. |
| Biperiden | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Biperiden. |
| Brompheniramine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Brompheniramine. |
| Flupentixol | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Flupentixol. |
| Cocaine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Cocaine. |
| Quinidine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Quinidine. |
| Maprotiline | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Maprotiline. |
| Methantheline | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Methantheline. |
| Cycrimine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Cycrimine. |
| Glycopyrronium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Glycopyrronium. |
| Tolterodine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Tolterodine. |
| Oxybutynin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Oxybutynin. |
| Promethazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Promethazine. |
| Diphenhydramine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Diphenhydramine. |
| Doxacurium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Doxacurium. |
| Doxepin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Doxepin. |
| Flavoxate | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Flavoxate. |
| Desipramine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Desipramine. |
| Orphenadrine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Orphenadrine. |
| Escitalopram | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Escitalopram. |
| Quetiapine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Quetiapine. |
| Mivacurium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Mivacurium. |
| Diphenidol | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Diphenidol. |
| Aripiprazole | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Aripiprazole. |
| Chlorprothixene | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Chlorprothixene. |
| Metocurine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Metocurine. |
| Pancuronium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Pancuronium. |
| Pipecuronium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Pipecuronium. |
| Methotrimeprazine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Methotrimeprazine. |
| Tiotropium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Tiotropium. |
| Solifenacin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Solifenacin. |
| Isopropamide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Isopropamide. |
| Rapacuronium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Rapacuronium. |
| Mepenzolate | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Mepenzolate. |
| Pizotifen | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Pizotifen. |
| Fesoterodine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Fesoterodine. |
| Hexocyclium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Hexocyclium. |
| Dimetindene | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Dimetindene. |
| Aclidinium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Aclidinium. |
| Dexetimide | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Dexetimide. |
| Benactyzine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Benactyzine. |
| Umeclidinium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Umeclidinium. |
| Trimebutine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Trimebutine. |
| Dosulepin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Dosulepin. |
| Imidafenacin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Imidafenacin. |
| Butylscopolamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Butylscopolamine. |
| Thonzylamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Thonzylamine. |
| Methscopolamine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Methscopolamine. |
| Revefenacin | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Revefenacin. |
| Oxitropium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Oxitropium. |
| Propiverine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Propiverine. |
| Batefenterol | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Batefenterol. |
| Mebeverine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Mebeverine. |
| Tropatepine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Tropatepine. |
| Prifinium | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Prifinium. |
| Piperidolate | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Piperidolate. |
| Benzilone | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Benzilone. |
| Difemerine | The therapeutic efficacy of Polycarbophil can be decreased when used in combination with Difemerine. |