Oxaprotiline is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. This drug was never marketed. Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). Both enantiomers have antidepressant effects but levoprotiline also is an antihistamine and dextroprotiline has many other pharmacological actions.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Valsartan | Oxaprotiline may decrease the antihypertensive activities of Valsartan. |
| Ramipril | Oxaprotiline may decrease the antihypertensive activities of Ramipril. |
| Esmolol | Oxaprotiline may decrease the antihypertensive activities of Esmolol. |
| Betaxolol | Oxaprotiline may decrease the antihypertensive activities of Betaxolol. |
| Remikiren | Oxaprotiline may decrease the antihypertensive activities of Remikiren. |
| Torasemide | Oxaprotiline may decrease the antihypertensive activities of Torasemide. |
| Guanadrel | Oxaprotiline may decrease the antihypertensive activities of Guanadrel. |
| Metoprolol | Oxaprotiline may decrease the antihypertensive activities of Metoprolol. |
| Isradipine | Oxaprotiline may decrease the antihypertensive activities of Isradipine. |
| Olmesartan | Oxaprotiline may decrease the antihypertensive activities of Olmesartan. |
| Chlorthalidone | Oxaprotiline may decrease the antihypertensive activities of Chlorthalidone. |
| Nitroprusside | Oxaprotiline may decrease the antihypertensive activities of Nitroprusside. |
| Atenolol | Oxaprotiline may decrease the antihypertensive activities of Atenolol. |
| Diltiazem | Oxaprotiline may decrease the antihypertensive activities of Diltiazem. |
| Minoxidil | Oxaprotiline may decrease the antihypertensive activities of Minoxidil. |
| Timolol | Oxaprotiline may decrease the antihypertensive activities of Timolol. |
| Treprostinil | Oxaprotiline may decrease the antihypertensive activities of Treprostinil. |
| Amlodipine | Oxaprotiline may decrease the antihypertensive activities of Amlodipine. |
| Nimodipine | Oxaprotiline may decrease the antihypertensive activities of Nimodipine. |
| Nisoldipine | Oxaprotiline may decrease the antihypertensive activities of Nisoldipine. |
| Bendroflumethiazide | Oxaprotiline may decrease the antihypertensive activities of Bendroflumethiazide. |
| Prazosin | Oxaprotiline may decrease the antihypertensive activities of Prazosin. |
| Fosinopril | Oxaprotiline may decrease the antihypertensive activities of Fosinopril. |
| Trandolapril | Oxaprotiline may decrease the antihypertensive activities of Trandolapril. |
| Metolazone | Oxaprotiline may decrease the antihypertensive activities of Metolazone. |
| Lercanidipine | Oxaprotiline may decrease the antihypertensive activities of Lercanidipine. |
| Benazepril | Oxaprotiline may decrease the antihypertensive activities of Benazepril. |
| Bosentan | Oxaprotiline may decrease the antihypertensive activities of Bosentan. |
| Propranolol | Oxaprotiline may decrease the antihypertensive activities of Propranolol. |
| Enalapril | Oxaprotiline may decrease the antihypertensive activities of Enalapril. |
| Doxazosin | Oxaprotiline may decrease the antihypertensive activities of Doxazosin. |
| Labetalol | Oxaprotiline may decrease the antihypertensive activities of Labetalol. |
| Cyclothiazide | Oxaprotiline may decrease the antihypertensive activities of Cyclothiazide. |
| Bisoprolol | Oxaprotiline may decrease the antihypertensive activities of Bisoprolol. |
| Candoxatril | Oxaprotiline may decrease the antihypertensive activities of Candoxatril. |
| Losartan | Oxaprotiline may decrease the antihypertensive activities of Losartan. |
| Moexipril | Oxaprotiline may decrease the antihypertensive activities of Moexipril. |
| Eplerenone | Oxaprotiline may decrease the antihypertensive activities of Eplerenone. |
| Lisinopril | Oxaprotiline may decrease the antihypertensive activities of Lisinopril. |
| Nitroglycerin | Oxaprotiline may decrease the antihypertensive activities of Nitroglycerin. |
| Hydroflumethiazide | Oxaprotiline may decrease the antihypertensive activities of Hydroflumethiazide. |
| Cryptenamine | Oxaprotiline may decrease the antihypertensive activities of Cryptenamine. |
| Perindopril | Oxaprotiline may decrease the antihypertensive activities of Perindopril. |
| Candesartan cilexetil | Oxaprotiline may decrease the antihypertensive activities of Candesartan cilexetil. |
| Fenoldopam | Oxaprotiline may decrease the antihypertensive activities of Fenoldopam. |
| Indapamide | Oxaprotiline may decrease the antihypertensive activities of Indapamide. |
| Tadalafil | Oxaprotiline may decrease the antihypertensive activities of Tadalafil. |
| Eprosartan | Oxaprotiline may decrease the antihypertensive activities of Eprosartan. |
| Chlorothiazide | Oxaprotiline may decrease the antihypertensive activities of Chlorothiazide. |
| Quinapril | Oxaprotiline may decrease the antihypertensive activities of Quinapril. |
| Telmisartan | Oxaprotiline may decrease the antihypertensive activities of Telmisartan. |
| Hydrochlorothiazide | Oxaprotiline may decrease the antihypertensive activities of Hydrochlorothiazide. |
| Trichlormethiazide | Oxaprotiline may decrease the antihypertensive activities of Trichlormethiazide. |
| Felodipine | Oxaprotiline may decrease the antihypertensive activities of Felodipine. |
| Irbesartan | Oxaprotiline may decrease the antihypertensive activities of Irbesartan. |
| Nitrendipine | Oxaprotiline may decrease the antihypertensive activities of Nitrendipine. |
| Deserpidine | Oxaprotiline may decrease the antihypertensive activities of Deserpidine. |
| Diazoxide | Oxaprotiline may decrease the antihypertensive activities of Diazoxide. |
| Carvedilol | Oxaprotiline may decrease the antihypertensive activities of Carvedilol. |
| Bretylium | Oxaprotiline may decrease the antihypertensive activities of Bretylium. |
| Terazosin | Oxaprotiline may decrease the antihypertensive activities of Terazosin. |
| Guanethidine | Oxaprotiline may decrease the antihypertensive activities of Guanethidine. |
| Acebutolol | Oxaprotiline may decrease the antihypertensive activities of Acebutolol. |
| Captopril | Oxaprotiline may decrease the antihypertensive activities of Captopril. |
| Nadolol | Oxaprotiline may decrease the antihypertensive activities of Nadolol. |
| Epoprostenol | Oxaprotiline may decrease the antihypertensive activities of Epoprostenol. |
| Bepridil | Oxaprotiline may decrease the antihypertensive activities of Bepridil. |
| Hydralazine | Oxaprotiline may decrease the antihypertensive activities of Hydralazine. |
| Bevantolol | Oxaprotiline may decrease the antihypertensive activities of Bevantolol. |
| Practolol | Oxaprotiline may decrease the antihypertensive activities of Practolol. |
| Polythiazide | Oxaprotiline may decrease the antihypertensive activities of Polythiazide. |
| Cilazapril | Oxaprotiline may decrease the antihypertensive activities of Cilazapril. |
| Saprisartan | Oxaprotiline may decrease the antihypertensive activities of Saprisartan. |
| Spirapril | Oxaprotiline may decrease the antihypertensive activities of Spirapril. |
| Mibefradil | Oxaprotiline may decrease the antihypertensive activities of Mibefradil. |
| Dexpropranolol | Oxaprotiline may decrease the antihypertensive activities of Dexpropranolol. |
| Tienilic acid | Oxaprotiline may decrease the antihypertensive activities of Tienilic acid. |
| Debrisoquine | Oxaprotiline may decrease the antihypertensive activities of Debrisoquine. |
| Sitaxentan | Oxaprotiline may decrease the antihypertensive activities of Sitaxentan. |
| Ambrisentan | Oxaprotiline may decrease the antihypertensive activities of Ambrisentan. |
| Diethylnorspermine | Oxaprotiline may decrease the antihypertensive activities of Diethylnorspermine. |
| Nilvadipine | Oxaprotiline may decrease the antihypertensive activities of Nilvadipine. |
| Pinacidil | Oxaprotiline may decrease the antihypertensive activities of Pinacidil. |
| Bupranolol | Oxaprotiline may decrease the antihypertensive activities of Bupranolol. |
| Temocapril | Oxaprotiline may decrease the antihypertensive activities of Temocapril. |
| Riociguat | Oxaprotiline may decrease the antihypertensive activities of Riociguat. |
| Macitentan | Oxaprotiline may decrease the antihypertensive activities of Macitentan. |
| Indenolol | Oxaprotiline may decrease the antihypertensive activities of Indenolol. |
| Aliskiren | Oxaprotiline may decrease the antihypertensive activities of Aliskiren. |
| Trimazosin | Oxaprotiline may decrease the antihypertensive activities of Trimazosin. |
| Efonidipine | Oxaprotiline may decrease the antihypertensive activities of Efonidipine. |
| Lacidipine | Oxaprotiline may decrease the antihypertensive activities of Lacidipine. |
| Manidipine | Oxaprotiline may decrease the antihypertensive activities of Manidipine. |
| Niguldipine | Oxaprotiline may decrease the antihypertensive activities of Niguldipine. |
| Rauwolfia serpentina root | Oxaprotiline may decrease the antihypertensive activities of Rauwolfia serpentina root. |
| Enalaprilat | Oxaprotiline may decrease the antihypertensive activities of Enalaprilat. |
| Selexipag | Oxaprotiline may decrease the antihypertensive activities of Selexipag. |
| Angiotensin 1-7 | Oxaprotiline may decrease the antihypertensive activities of Angiotensin 1-7. |
| Talinolol | Oxaprotiline may decrease the antihypertensive activities of Talinolol. |
| Imidapril | Oxaprotiline may decrease the antihypertensive activities of Imidapril. |