It is reported to present a moderate liver toxicity.A32048 In preclinical studies, the acute toxicity was analyzed when administered orally and intravenously. The LD50 of imolamine was 650 mg/kg and 250 mg/kg for oral and intravenous administration, respectively.MSDS
Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethylamine. It is developed under the brand name Coremax by Novartis consumer health SA.
Fitur visualisasi ini dikembangkan menggunakan pendekatan Graph Theory untuk memetakan hubungan polifarmasi dan molekuler. Entitas (Obat, Target, Gen) direpresentasikan sebagai Simpul (Nodes), sedangkan hubungan biologisnya sebagai Sisi (Edges).
drugbank-id dan name pada skema XML DrugBank.targets/target yang memuat polipeptida sasaran.gene-name dan varian snp-effects.Tata letak grafik menggunakan algoritma Force-Directed Graph (Barnes-Hut). Model fisika ini menerapkan gaya tolak-menolak antar simpul (Gravitasi: -3000) agar tidak tumpang tindih, serta gaya pegas (Spring: 0.04) pada garis penghubung untuk fleksibilitas interaksi.
| Patent Blue | The therapeutic efficacy of Imolamine can be decreased when used in combination with Patent Blue. |
| Isosorbide mononitrate | Imolamine may increase the vasodilatory activities of Isosorbide mononitrate. |
| Iloprost | Iloprost may increase the hypotensive activities of Imolamine. |