Parnaparin

DB09260

small molecule approved investigational

Deskripsi

Parnaparin is an heparin of low molecular weight with antithrombotic effects.

Struktur Molekul 2D

Struktur tidak tersedia

Peta Jejaring Molekuler
Legenda: ObatTargetGenEnzim(Panah → menunjukkan arah efek / relasi)TransporterCarrier

Profil Farmakokinetik

Waktu Paruh (Half-Life) -
Volume Distribusi -
Klirens (Clearance) -

Absorpsi

Data absorpsi tidak tersedia.

Metabolisme

Data metabolisme tidak tersedia.

Rute Eliminasi

Data eliminasi belum tersedia.

Interaksi Makanan

1 Data
  • 1. Avoid herbs and supplements with anticoagulant/antiplatelet activity. Examples include garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

Interaksi Obat

860 Data
Apixaban Apixaban may increase the anticoagulant activities of Parnaparin.
Dabigatran etexilate Dabigatran etexilate may increase the anticoagulant activities of Parnaparin.
Dasatinib The risk or severity of bleeding and hemorrhage can be increased when Dasatinib is combined with Parnaparin.
Deferasirox The risk or severity of gastrointestinal bleeding can be increased when Parnaparin is combined with Deferasirox.
Ursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Ursodeoxycholic acid.
Glycochenodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Glycochenodeoxycholic Acid.
Cholic Acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Cholic Acid.
Glycocholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Glycocholic acid.
Deoxycholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Deoxycholic acid.
Taurocholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Taurocholic acid.
Obeticholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Obeticholic acid.
Chenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Chenodeoxycholic acid.
Taurochenodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Taurochenodeoxycholic acid.
Tauroursodeoxycholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Tauroursodeoxycholic acid.
Bamet-UD2 The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Bamet-UD2.
Dehydrocholic acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Dehydrocholic acid.
Hyodeoxycholic Acid The risk or severity of bleeding and bruising can be increased when Parnaparin is combined with Hyodeoxycholic Acid.
Edoxaban The risk or severity of bleeding can be increased when Edoxaban is combined with Parnaparin.
Ibrutinib The risk or severity of bleeding and hemorrhage can be increased when Ibrutinib is combined with Parnaparin.
Obinutuzumab The risk or severity of bleeding and hemorrhage can be increased when Parnaparin is combined with Obinutuzumab.
Rivaroxaban Parnaparin may increase the anticoagulant activities of Rivaroxaban.
Sugammadex The risk or severity of bleeding and hemorrhage can be increased when Parnaparin is combined with Sugammadex.
Tibolone Tibolone may increase the anticoagulant activities of Parnaparin.
Tipranavir The risk or severity of bleeding and hemorrhage can be increased when Tipranavir is combined with Parnaparin.
Urokinase Urokinase may increase the anticoagulant activities of Parnaparin.
Vitamin E Vitamin E may increase the anticoagulant activities of Parnaparin.
Vorapaxar The risk or severity of bleeding and hemorrhage can be increased when Vorapaxar is combined with Parnaparin.
Trandolaprilat The risk or severity of hyperkalemia can be increased when Trandolaprilat is combined with Parnaparin.
Moexiprilat The risk or severity of hyperkalemia can be increased when Moexiprilat is combined with Parnaparin.
Cilazaprilat The risk or severity of hyperkalemia can be increased when Cilazaprilat is combined with Parnaparin.
Ginkgo biloba Ginkgo biloba may increase the anticoagulant activities of Parnaparin.
Ifosfamide The risk or severity of bleeding can be increased when Ifosfamide is combined with Parnaparin.
Quinine The therapeutic efficacy of Parnaparin can be increased when used in combination with Quinine.
Quinidine The therapeutic efficacy of Parnaparin can be increased when used in combination with Quinidine.
Tamoxifen The risk or severity of bleeding can be increased when Tamoxifen is combined with Parnaparin.
Toremifene The risk or severity of bleeding can be increased when Toremifene is combined with Parnaparin.
Corticorelin ovine triflutate The risk or severity of hypotension and sinus node depression can be increased when Parnaparin is combined with Corticorelin ovine triflutate.
Oritavancin The therapeutic efficacy of Parnaparin can be decreased when used in combination with Oritavancin.
Streptokinase Streptokinase may increase the anticoagulant activities of Parnaparin.
Telavancin The therapeutic efficacy of Parnaparin can be decreased when used in combination with Telavancin.
Palifermin The serum concentration of Palifermin can be increased when it is combined with Parnaparin.
Pentoxifylline The therapeutic efficacy of Parnaparin can be increased when used in combination with Pentoxifylline.
Pentosan polysulfate Pentosan polysulfate may increase the anticoagulant activities of Parnaparin.
Levocarnitine The therapeutic efficacy of Parnaparin can be increased when used in combination with Levocarnitine.
Diethylstilbestrol Diethylstilbestrol may decrease the anticoagulant activities of Parnaparin.
Chlorotrianisene Chlorotrianisene may decrease the anticoagulant activities of Parnaparin.
Conjugated estrogens Conjugated estrogens may decrease the anticoagulant activities of Parnaparin.
Mestranol The risk or severity of adverse effects can be increased when Mestranol is combined with Parnaparin.
Estrone sulfate Estrone sulfate may decrease the anticoagulant activities of Parnaparin.
Quinestrol Quinestrol may decrease the anticoagulant activities of Parnaparin.
Hexestrol Hexestrol may decrease the anticoagulant activities of Parnaparin.
Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may decrease the anticoagulant activities of Parnaparin.
Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may decrease the anticoagulant activities of Parnaparin.
Polyestradiol phosphate Polyestradiol phosphate may decrease the anticoagulant activities of Parnaparin.
Esterified estrogens Esterified estrogens may decrease the anticoagulant activities of Parnaparin.
Zeranol Zeranol may decrease the anticoagulant activities of Parnaparin.
Equol Equol may decrease the anticoagulant activities of Parnaparin.
Methallenestril Methallenestril may decrease the anticoagulant activities of Parnaparin.
Epimestrol Epimestrol may decrease the anticoagulant activities of Parnaparin.
Moxestrol Moxestrol may decrease the anticoagulant activities of Parnaparin.
Estradiol acetate Estradiol acetate may decrease the anticoagulant activities of Parnaparin.
Estradiol benzoate Estradiol benzoate may decrease the anticoagulant activities of Parnaparin.
Estradiol cypionate Estradiol cypionate may decrease the anticoagulant activities of Parnaparin.
Estradiol valerate Estradiol valerate may decrease the anticoagulant activities of Parnaparin.
Biochanin A Biochanin A may decrease the anticoagulant activities of Parnaparin.
Formononetin Formononetin may decrease the anticoagulant activities of Parnaparin.
Estriol Estriol may decrease the anticoagulant activities of Parnaparin.
Limaprost The risk or severity of adverse effects can be increased when Limaprost is combined with Parnaparin.
Icosapent The risk or severity of bleeding and hemorrhage can be increased when Icosapent is combined with Parnaparin.
Mesalazine The risk or severity of bleeding can be increased when Mesalazine is combined with Parnaparin.
Indomethacin The risk or severity of bleeding and hemorrhage can be increased when Indomethacin is combined with Parnaparin.
Nabumetone The risk or severity of bleeding and hemorrhage can be increased when Nabumetone is combined with Parnaparin.
Ketorolac The risk or severity of bleeding and hemorrhage can be increased when Ketorolac is combined with Parnaparin.
Tenoxicam The risk or severity of bleeding and hemorrhage can be increased when Tenoxicam is combined with Parnaparin.
Celecoxib The risk or severity of bleeding and hemorrhage can be increased when Celecoxib is combined with Parnaparin.
Tolmetin The risk or severity of bleeding and hemorrhage can be increased when Tolmetin is combined with Parnaparin.
Rofecoxib The risk or severity of bleeding and hemorrhage can be increased when Rofecoxib is combined with Parnaparin.
Piroxicam The risk or severity of bleeding and hemorrhage can be increased when Piroxicam is combined with Parnaparin.
Fenoprofen The risk or severity of bleeding and hemorrhage can be increased when Fenoprofen is combined with Parnaparin.
Valdecoxib The risk or severity of bleeding and hemorrhage can be increased when Valdecoxib is combined with Parnaparin.
Diclofenac The risk or severity of bleeding and hemorrhage can be increased when Diclofenac is combined with Parnaparin.
Sulindac The risk or severity of bleeding and hemorrhage can be increased when Sulindac is combined with Parnaparin.
Flurbiprofen The risk or severity of bleeding and hemorrhage can be increased when Flurbiprofen is combined with Parnaparin.
Etodolac The risk or severity of bleeding and hemorrhage can be increased when Etodolac is combined with Parnaparin.
Mefenamic acid The risk or severity of bleeding and hemorrhage can be increased when Mefenamic acid is combined with Parnaparin.
Naproxen The risk or severity of bleeding and hemorrhage can be increased when Naproxen is combined with Parnaparin.
Sulfasalazine The risk or severity of bleeding and hemorrhage can be increased when Sulfasalazine is combined with Parnaparin.
Phenylbutazone The risk or severity of bleeding and hemorrhage can be increased when Phenylbutazone is combined with Parnaparin.
Meloxicam The risk or severity of bleeding and hemorrhage can be increased when Meloxicam is combined with Parnaparin.
Carprofen The risk or severity of bleeding and hemorrhage can be increased when Carprofen is combined with Parnaparin.
Diflunisal The risk or severity of bleeding and hemorrhage can be increased when Diflunisal is combined with Parnaparin.
Salicylic acid The risk or severity of bleeding and hemorrhage can be increased when Salicylic acid is combined with Parnaparin.
Meclofenamic acid The risk or severity of bleeding and hemorrhage can be increased when Meclofenamic acid is combined with Parnaparin.
Oxaprozin The risk or severity of bleeding and hemorrhage can be increased when Oxaprozin is combined with Parnaparin.
Ketoprofen The risk or severity of bleeding and hemorrhage can be increased when Ketoprofen is combined with Parnaparin.
Balsalazide The risk or severity of bleeding and hemorrhage can be increased when Balsalazide is combined with Parnaparin.
Olsalazine The risk or severity of bleeding can be increased when Parnaparin is combined with Olsalazine.
Lumiracoxib The risk or severity of bleeding and hemorrhage can be increased when Lumiracoxib is combined with Parnaparin.
Magnesium salicylate The risk or severity of bleeding and hemorrhage can be increased when Magnesium salicylate is combined with Parnaparin.
Salsalate The risk or severity of bleeding and hemorrhage can be increased when Salsalate is combined with Parnaparin.

Referensi & Sumber

Artikel (PubMed)
  • PMID: 17549299
    Maugeri N, Di Fabio G, Barbanti M, de Gaetano G, Donati MB, Cerletti C: Parnaparin, a low-molecular-weight heparin, prevents P-selectin-dependent formation of platelet-leukocyte aggregates in human whole blood. Thromb Haemost. 2007 Jun;97(6):965-73.

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